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产品数:86101
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TP1898HS024selective,melanocortin,intake,Inhibitor,Melanocortin Receptor,MC Receptor,HS-024,food,HS024,inh
Highly potent melanocortin MC4 receptor antagonist (Ki values are 0.29, 18.6, 5.45 and 3.29 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake, and blocks α-MSH- and MTII-induced hypotension and bradycardia in rats, following central administration in vivo.
价 格:¥电议型 号:TP1898产 地:中国大陆
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TN71894,6-Dibromoindole
4,6-Dibromoindole is a marine derived natural products found in Glossobalanus sp.
价 格:¥电议型 号:TN7189产 地:中国大陆
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T6S1894LinderaneCYPs,Cytochrome P450,Linderane,inhibit,Inhibitor
1. Linderane was characterized as a mechanism-based inactivator of CYP2C9.
价 格:¥电议型 号:T6S1894产 地:中国大陆
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T18946Cy3 NHS ester
Cy3 NHS ester is a fluorescent dye for labeling amino groups in proteins, peptides, antibodies, and oligonucleotides.
价 格:¥电议型 号:T18946产 地:中国大陆
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T9072TuxobertinibTuxobertinib,inhibit,ErbB-1,EGFR,BDTX 189,BDTX189,mutants,Epidermal growth factor recept
BDTX-189 is a potent and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations(KDs of 0.2, 0.76, 13 and 1.2 nM for EGFR, HER2, BLK and RIPK2, reapectively). BDTX-189 exhibits anticancer activity.
价 格:¥电议型 号:T9072产 地:中国大陆
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TP1895L1KYL acetate(676657-00-4 free base)KYL acetate(676657 00 4 free base),KYL acetate(676657004 free base
EphA4 receptor tyrosine kinase inhibitor (Kd = 0.8 μM); inhibits EphA4-EphrinA5 interactions (IC50 = 6.34 μM). Prevents AβO induced synaptic damage, dendritic spine loss and prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. Exhibits a long half life in cell culture media (8 and 12 hours in PC3 and C2C12 media respectively). Neuroprotective.
价 格:¥电议型 号:TP1895L1产 地:中国大陆
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TP1893L1[D-Trp8]-γ-MSH acetate(321351-81-9 free base)[D Trp8] γ MSH acetate(321351 81 9 free base),[DTrp8]γM
Selective melanocortin 3 (MC3) receptor agonist (IC50 values are 6.7, 340 and 600 nM for human MC3, MC5 and MC4 receptors respectively). Displays anti-inflammatory efficacy.
价 格:¥电议型 号:TP1893L1产 地:中国大陆
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T21714BMS453Inhibitor,BMS453,retinoid,RAR/RXR,inhibit,BMS-453,BMS 189453,TGFβ,breast,RARβ,RARγ,Retinoid X
BMS453, a synthetic retinoid, is a potent and selective agonist of RARβ and a potent testicular toxin. BMS453 inhibits breast cell growth predominantly through the induction of active TGFβ.
价 格:¥电议型 号:T21714产 地:中国大陆
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T7189AMG9810Transient receptor potential channels,inhibit,Inhibitor,AMG-9810,AMG9810,AMG 9810,TRP Channel
AMG 9810 is a competitive antagonist of capsaicin activation of the vanilloid receptor 1 (TRPV1) (IC50s = 24.5 and 85.6 nM for human and rat TRPV1, respectively).
价 格:¥电议型 号:T7189产 地:中国大陆
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TP1896L1Kisspeptin 234 acetate(1145998-81-7 free base)Kisspeptin 234 acetate(1145998 81 7 free base),Kisspep
kisspeptin receptor (KISS1, GPR54) antagonist; kisspeptin-10 analog. Inhibits kisspeptin-10 stimulation of inositol phosphate (IP) (IC50 = 7 nM) and release of gonadotrophin-releasing hormone (GnRH).
价 格:¥电议型 号:TP1896L1产 地:中国大陆
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T9596AP1189 acetateAP1189 acetate,AP-1189 acetate
AP1189 acetate is a biased agonist at melanocortin 1 and melanocortin 3 receptors.
价 格:¥电议型 号:T9596产 地:中国大陆
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T61189E7016
E7016 is an orally available PARP inhibitor. E7016 inhibits of DNA repair. E7016 can enhance tumor cell radiosensitivity in vitro and in vivo.
价 格:¥电议型 号:T61189产 地:中国大陆
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TP1899L1Hemokinin 1 (human) acetate(491851-53-7 free base)Hemokinin 1 (human) acetate(491851537 free base),H
Hemokinin 1 (human) acetate is an endogenous substance P homolog that is a selective agonist at the tachykinin NK1 receptor (IC50 values are 1.8, 370 and 480 nM for NK1, NK3 and NK2 receptors respectively). Has proliferative and antiapoptotic actions on B-cells in vitro and is antihypertensive in vivo.
价 格:¥电议型 号:TP1899L1产 地:中国大陆
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TN1895Luteolinidin chlorideInhibitor,I/R,reperfusion,inhibit,CD38,Luteolinidin,Ischemia,trans-chalcone,Lut
Luteolinidin chloride is a natural product. It is a potent CD38 inhibitor which can protect the heart against I/R injury with preservation of eNOS function and prevention of endothelial dysfunction in vivo.
价 格:¥电议型 号:TN1895产 地:中国大陆
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TP1419LHAEGTFT acetate(926018-95-3 free base)HAEGTFT acetate(926018 95 3 free base),HAEGTFT acetate(9260189
HAEGTFT acetate is the first N-terminal 1-7 residues of GLP-1 peptide.
价 格:¥电议型 号:TP1419L产 地:中国大陆
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TQ0225VelsecoratAZD 7594,Inhibitor,AZD-7594,Velsecorat,Glucocorticoid Receptor,AZ-13189620,AZ 13189620,inh
AZD7594 is an effective and selective nonsteroidal glucocorticoid receptor modulator (IC50: 0.9 nM).
价 格:¥电议型 号:TQ0225产 地:中国大陆
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T9466RTICBM-189Brain,Inhibitor,RTICBM-189,inhibit,Cocaine,RTICBM 189,Allosteric,Penetrant,Cannabinoid Rec
RTICBM-189 is Brain Penetrant and Attenuates Reinstatement of Cocaine-Seeking Behavior.
价 格:¥电议型 号:T9466产 地:中国大陆
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TP1890L1MLCK inhibitor peptide 18 acetateMLCK inhibitor peptide 18 acetate
MLCK inhibitor peptide 18 acetate is a selective competitive inhibitor of myosin light chain kinase (IC50 = 50 nM). Displays 4000-fold selectivity over CaM kinase II and does not inhibit PKA. Cell permeable.
价 格:¥电议型 号:TP1890L1产 地:中国大陆
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TN118913-Methylberberine chlorideinhibit,Inhibitor,13 Methylberberine chloride,13Methylberberine chloride,
13-Methylberberine shows anti-adipogenic effect on 3T3-L1 adipocytes, it has potential as an anti-obesity drug
价 格:¥电议型 号:TN1189产 地:中国大陆
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TP1897L1JIP-1 (153-163) acetate(438567-88-5 free base)JIP1 (153163) acetate(438567885 free base),JIP 1 (153
Peptide inhibitor of c-Jun N-terminal kinase (JNK), based on residues 153-163 of JNK-interacting protein-1 (JIP-1). Binds to JNK with affinity in the micromolar range and minimally inhibits p38 and ERK.
价 格:¥电议型 号:TP1897L1产 地:中国大陆