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  • T7568LM22A-4LM-22A-4,Inhibitor,Trk Receptor,inhibit,LM22A4,LM22A-4,Tropomyosin related kinase receptor,LM

    LM22A-4 is a brain-derived neurotrophic factor (BDNF) mimetic and agonist of the receptor tropomyosin-related kinase B (TrkB; IC50 : 47 nM in a fluorescence anisotropy assay)

    价 格：￥电议型 号：T7568产 地：中国大陆

  • T23440TC-N 22ATCN 22A,TC N 22A

    mGlu4 receptor positive allosteric modulator

    价 格：￥电议型 号：T23440产 地：中国大陆

  • T9043AS1810722AS-1810722,inhibit,CYPs,AS 1810722,Cytochrome P450,eosinophil,allergic,AS1810722,STAT,orall

    AS1810722 is an orally active and potent STAT6 inhibitor(IC50 :1.9 nM). AS1810722 shows a good profile of CYP3A4 inhibition. AS1810722, a derivative of fused bicyclic pyrimidine, has the potential for allergic diseases such as asthma and atopic diseases research.

    价 格：￥电议型 号：T9043产 地：中国大陆

  • T6875LesinuradRDEA 594,RDEA-594,SLC22A12,Inhibitor,Lesinurad,inhibit,URAT1,Urate transporter 1

    Lesinurad is a selective inhibitor of uric acid reabsorption which is used in combination with other agents in the therapy of gout. Lesinurad has had a limited clinical use but has not been associated with serum enzyme elevations during therapy or with instances of clinically apparent liver injury.

    价 格：￥电议型 号：T6875产 地：中国大陆

  • T27467GSK270822AGSK270822A

    GSK270822A is a selective ROCK1 inhibitor. GSK270822A exhibits IC50 of 9nM, 1100nM, 1550nM for ROCK1, RSK1, p70S6K, respectively.

    价 格：￥电议型 号：T27467产 地：中国大陆

  • T10202A 1070722A 1070722

    A 1070722 is a potent and selective GSK-3 inhibitor, with a Ki of 0.6 nM for both GSK-3α and GSK-3β. It can penetrate the blood-brain barrier (BBB) and accumulates in brain regions, thus potential for PET radiotracer for the quantification of GSK-3 in bra

    价 格：￥电议型 号：T10202产 地：美洲

  • T16497PF 1022APF 1022A

    PF 1022A is an N-methylated cyclooctadepsipeptides with strong anthelmintic properties. It also acts as an ionosphere.

    价 格：￥电议型 号：T16497产 地：美洲

  • T83197Acetyl tetrapeptide-22；化合物 Acetyl tetrapeptide-22Acetyl tetrapeptide-22

    Acetyl Tetrapeptide-22 is a bioactive peptide known for its skin repair effects and is commonly utilized as a cosmetic ingredient [1].

    价 格：￥电议型 号：T83197产 地：中国大陆

  • T80535AMPR-22；化合物 AMPR-22AMPR-22

    AMPR-22, an antimicrobial peptide, binds to bacterial membranes to induce permeabilization and has demonstrated efficacy in a murine sepsis model induced by multidrug-resistant (MDR) strains [1].

    价 格：￥电议型 号：T80535产 地：中国大陆

  • T79633Antileishmanial agent-22；化合物 Antileishmanial agent-22Antileishmanial agent-22

    Antileishmanial agent-22 (compound 15b) serves as an antiparasitic and antibacterial, exhibiting activities against Leishmania (IC50 = 0.408 μM), malaria, and tuberculosis. It operates on an antifolate mechanism, suppressing both folic and folinic acids with 88% and 94% efficacy at 100 μM, respectively. This compound also demonstrates a 96.67% inhibitory effect on P. berghei in vivo/in vitro at 48.4 μM/kg/day and 0.038 μM (IC50), and it inhibits M. tuberculosis with an MIC of 28.44 μM [1].

    价 格：￥电议型 号：T79633产 地：中国大陆

  • T79468Antimicrobial agent-22；化合物 Antimicrobial agent-22Antimicrobial agent-22

    Antimicrobial agent-22 (THI 6c) constitutes a broad-spectrum, multi-target antibacterial with notable rapid bactericidal efficacy and effective anti-biofilm activity, paired with low cytotoxicity and hemolytic properties [1].

    价 格：￥电议型 号：T79468产 地：中国大陆

  • T79204Anticancer agent 122；化合物 Anticancer agent 122Anticancer agent 122

    Anticancer agent 122, a potent inhibitor of human lactate dehydrogenase A (h LDHA), exhibits significant anticancer activities, rendering it suitable for use in cancer research [1].

    价 格：￥电议型 号：T79204产 地：中国大陆

  • T79033ATR-IN-22；化合物 ATR-IN-22ATR-IN-22

    ATR-IN-22 (Compound 34), an orally active ATR inhibitor, exhibits potent anti-proliferative effects on MIAPaCa-2 cells with an IC50 value of less than 1 μM and demonstrates anti-tumor activity in colon cancer [1].

    价 格：￥电议型 号：T79033产 地：中国大陆

  • T7568LM22A-4；化合物LM22A-4LM22A-4

    LM22A-4 is a brain-derived neurotrophic factor (BDNF) mimetic and agonist of the receptor tropomyosin-related kinase B (TrkB; IC50 : 47 nM in a fluorescence anisotropy assay)

    价 格：￥电议型 号：T7568产 地：中国大陆

  • T69206AL-38022A；化合物 AL-38022AAL-38022A

    AL-38022A is a novel synthetic serotonergic (5-HT) ligand that exhibited high affinity for each of the 5-HT2 receptor subtypes (Ki100-fold less) affinity for other 5-HT receptors. In addition, AL-38022A displayed a very low affinity for a broad array of other receptors, neurotransmitter transport sites, ion channels, and second messenger elements, making it a relatively selective agent. AL-38022A potently stimulated functional responses via native and clo

    价 格：￥电议型 号：T69206产 地：中国大陆

  • T63755Antitubercular agent-22；化合物 Antitubercular agent-22Antitubercular agent-22

    Antitubercular agent-22 (Compound 2) is an effective anti-Candida and anti-tuberculosis agent against Candida albicans MTCC 3017 (MIC: 2.34 μg/ml) and M. tuberculosis (H37Rv) (MIC: 2 μg/ml).

    价 格：￥电议型 号：T63755产 地：中国大陆

  • T63564ATX inhibitor 22；化合物 ATX inhibitor 22ATX inhibitor 22

    ATX inhibitor 22 is a novel inhibitor of ATX (autotaxin) (IC50: 218.9 μM) that lacks inhibitory activity against LPAR1.

    价 格：￥电议型 号：T63564产 地：中国大陆

  • T63130ALK-IN-22；化合物 ALK-IN-22ALK-IN-22

    ALK-IN-22 (compound I-24) is a potent inhibitor of ALK, acting on ALK (IC50: 2.3 nM), ALKL1196M (IC50: 3.7 nM), ALKG1202R (IC50: 2.9 nM). ALK-IN-22 down-regulates phosphorylation of ALK and its downstream proteins and induces apoptosis. ALK-IN-22 can be used to study tumors.

    价 格：￥电议型 号：T63130产 地：中国大陆

  • T62658Antifungal agent 22；化合物 Antifungal agent 22Antifungal agent 22

    Antifungal agent 22 (compound D16) is an orally active, potentially antifungal agent (IC50: 0.5 μg/mL) with blood-brain barrier permeability, good metabolic stability and low cytotoxicity. Antifungal agent 22 is a selective anti-cryptococcal agent that kills C. neoformansH99 cells by disrupting the integrity of the fungal cell membrane.

    价 格：￥电议型 号：T62658产 地：中国大陆

  • T62541AChE-IN-22；化合物 AChE-IN-22AChE-IN-22

    AChE-IN-22 (compound 10q) is a selective inhibitor of acetylcholinesterase (AChE) that acts on both AChE (IC50: 0.88 μM) and BuChE (IC50: 10 μM). AChE-IN-22 binds to both the CAS (catalytic active site) and PAS (peripheral anionic site) sites of AChE and can be used to study Alzheimer´s disease.

    价 格：￥电议型 号：T62541产 地：中国大陆

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