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T34863-MATIDA
3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a). Displays ≥ 40-fold selectivity over other receptors: mGluR-5, mGluR-2, mGluR-4 (mGluR-4a) (IC50 > 300 μM), NMDA and GluR (AMPA) (IC50 = 250 μM). 3-MATIDA act as a neuroprotectant in
价 格:¥电议型 号:T3486产 地:中国大陆
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T18793-MethyladenineNSC 66389;3-MA;3-甲基腺嘌呤
3-Methyladenine (3-MA) is a selective PI3KV inhibitor, and the IC50s against ps34 and PI3Kγ were 25/60 μM in HeLa cells, respectively.
价 格:¥电议型 号:T1879产 地:中国大陆
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T18793-Methyladenine3-Methyladenine,3-MA,NSC 66389
3-Methyladenine (3-MA) is a selective PI3KV inhibitor, and the IC50s against ps34 and PI3Kγ were 25/60 μM in HeLa cells, respectively.
价 格:¥电议型 号:T1879产 地:美洲
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T34863-MATIDA;化合物3-MATIDA3-MATIDA
3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a). Displays ≥ 40-fold selectivity over other receptors: mGluR-5, mGluR-2, mGluR-4 (mGluR-4a) (IC50 > 300 μM), NMDA and GluR (AMPA) (IC50 = 250 μM). 3-MATIDA act as a neuroprotectant in cultured murine cortical cells and rat hippocampal slice cultures in vitro.
价 格:¥电议型 号:T3486产 地:中国大陆
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T18793-Methyladenine;3-甲基腺嘌呤3-MA|||NSC 66389;3-MA|||3-甲基腺嘌呤|||NSC 66389
3-Methyladenine (3-MA) is a PI3K inhibitor that selectively inhibits class IB PI3Kγ (IC50=60 μM) and class III VPS34 (IC50=25 μM). 3-Methyladenine inhibits autophagy.
价 格:¥电议型 号:T1879产 地:中国大陆
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T18767TCO-PEG3-maleimide;化合物 T18767TCO-PEG3-maleimide
TCO-PEG3-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
价 格:¥电议型 号:T18767产 地:中国大陆
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T18179m-PEG3-Mal;化合物 T18179m-PEG3-Mal
m-PEG3-Mal is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T18179产 地:中国大陆
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T17935endo-BCN-PEG3-mal;化合物 T17935endo-BCN-PEG3-mal
endo-BCN-PEG3-mal is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17935产 地:中国大陆
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T15761Lipoamide-PEG3-Mal;化合物 T15761Lipoamide-PEG3-Mal
Lipoamide-PEG3-Mal is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T15761产 地:中国大陆
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T14593Biotin-PEG3-Mal;化合物 T14593Biotin-PEG3-Mal
Biotin-PEG3-Mal is a biotinylated polyethylene glycol (PEG) derivative used as a linker in the synthesis of proteolysis targeting chimeras (PROTACs). By introducing the biotin moiety, it enables specific recognition and binding to target proteins. Additionally, the PEG spacer contributes to improved solubility and flexibility of the linker. This compound offers a valuable tool for constructing PROTACs, which hold great potential in targeted protein degradation strategies[1].
价 格:¥电议型 号:T14593产 地:中国大陆
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T14429Azido-PEG3-maleimide;化合物 T14429Azido-PEG3-maleimide
Azido-PEG3-maleimide is a PEG-based PROTAC linker primarily used for the synthesis of PROTACs[1]. Additionally, it serves as a cleavable 3-unit PEG ADC linker employed in the synthesis of antibody-drug conjugates (ADCs)[2].
价 格:¥电议型 号:T14429产 地:中国大陆
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T140323-Maleimidopropionic acid;化合物 T140323-Maleimidopropionic acid
3-Maleimidopropionic acid is an alkyl chain-derived PROTAC linker employed in PROTAC synthesis[1].
价 格:¥电议型 号:T14032产 地:中国大陆