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T80657SARS-CoV-2 3CLpro-IN-15；化合物 SARS-CoV-2 3CLpro-IN-15SARS-CoV-2 3CLpro-IN-15
SARS-CoV-2 3CLpro-IN-15 (compound a), a beta-nitrostyrene derivative, acts as an inhibitor of the SARS-CoV-2 3CL protease (3CLpro), effectively inhibiting viral replication and transcription. It is instrumental in the identification of potential anti-COVID-19 lead compounds [1].
价 格：￥电议型 号：T80657产 地：中国大陆
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T79661SARS-CoV-2 3CLpro-IN-18；化合物 SARS-CoV-2 3CLpro-IN-18SARS-CoV-2 3CLpro-IN-18
SARS-CoV-2 3CLpro-IN-18 (Compound 3C) is a covalent inhibitor of SARS-CoV-2 3CLpro with an IC50 of 0.478 μM. It demonstrates inhibition of SARS-CoV-2 in Vero E6 cells, with an EC50 of 2.499 μM, and exhibits low cytotoxicity (CC50 > 200 μM) [1].
价 格：￥电议型 号：T79661产 地：中国大陆
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T79660SARS-CoV-2 3CLpro-IN-17；化合物 SARS-CoV-2 3CLpro-IN-17SARS-CoV-2 3CLpro-IN-17
Compound 3h, also known as SARS-CoV-2 3CLpro-IN-17, is a selective inhibitor of the SARS-CoV-2 3CL protease, demonstrating an IC50 of 0.322 μM [1].
价 格：￥电议型 号：T79660产 地：中国大陆
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T79659SARS-CoV-2 3CLpro-IN-16；SARS-CoV-2 3CLpro 抑制剂16SARS-CoV-2 3CLpro-IN-16
SARS-CoV-2 3CLpro-IN-16 is a covalent SARS-CoV-2 3CLpro inhibitor that inhibits 3CLpro activity and achieves its inhibitory effect by forming a covalent bond with Cys145.
价 格：￥电议型 号：T79659产 地：中国大陆
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T79462SARS-CoV-2 3CLpro-IN-14；化合物 SARS-CoV-2 3CLpro-IN-14SARS-CoV-2 3CLpro-IN-14
SARS-CoV-2 3CLpro-IN-14 (compound 11j) is an orally active inhibitor of SARS-CoV-2 3CLpro, demonstrating potent anti-SARS-CoV-2 properties with an EC50 of 0.18 μM and exhibits minimal cytotoxicity, having a CC50 greater than 50 μM, in Vero E6 cells [1].
价 格：￥电议型 号：T79462产 地：中国大陆
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T79376SARS-CoV-2 3CLpro-IN-19；化合物 SARS-CoV-2 3CLpro-IN-19SARS-CoV-2 3CLpro-IN-19
SARS-CoV-2 3CLpro-IN-19 (Compound C5a), a non-covalent, non-peptide inhibitor of the SARS-CoV-2 3CLpro enzyme, exhibits potent in vitro activity with an IC50 of 0.7 μM. It demonstrates broad-spectrum efficacy against infection by Omicron subvariants (BA.5, BQ.1.1, and XBB.1.5) in human cells, with EC50 values ranging from 30-69 nM [1].
价 格：￥电议型 号：T79376产 地：中国大陆
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T74807SARS-CoV-2 3CLpro-IN-13；化合物 SARS-CoV-2 3CLpro-IN-13SARS-CoV-2 3CLpro-IN-13
SARS-CoV-2 3CLpro-IN-13 is a potent inhibitor of the SARS-CoV-2 3CL protease, demonstrating significant anti-coronavirus activity with an IC50 value of 21 nM [1].
价 格：￥电议型 号：T74807产 地：中国大陆
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T72313SARS-CoV-2 3CLpro-IN-11；化合物 SARS-CoV-2 3CLpro-IN-11SARS-CoV-2 3CLpro-IN-11
SARS-CoV-2 3CLpro-IN-11(11d) is a broad-spectrum antiviral compound that effectively inhibits the SARS-CoV-2 3CL protease, achieving an IC50 of 140 nM. Additionally, it exhibits inhibitory activity against SARS-CoV-1 and MERS-CoV with IC50 values of 240 nM and 70 nM, respectively.
价 格：￥电议型 号：T72313产 地：中国大陆
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T72312SARS-CoV-2 3CLpro-IN-10；化合物 SARS-CoV-2 3CLpro-IN-10SARS-CoV-2 3CLpro-IN-10
SARS-CoV-2 3CLpro-IN-10(5d) is a potent inhibitor of the SARS-CoV-2 3CL protease, exhibiting an IC50 value of 190 nM, and demonstrates varied efficiency against other coronaviruses with IC50 values of 790 nM for SARS-CoV-1 and 70 nM for MERS-CoV, indicating broad-spectrum antiviral activity.
价 格：￥电议型 号：T72312产 地：中国大陆
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T63537SARS-CoV-2 3CLpro-IN-1；化合物 SARS-CoV-2 3CLpro-IN-1SARS-CoV-2 3CLpro-IN-1
SARS-CoV-2 3CLpro-IN-1 (Compound 14c) is a highly potent inhibitor specifically designed to target and inhibit the activity of SARS-CoV-2 3CL pro, which is a cysteine-protease found in the main coronaviruses. This particular enzyme has been recognized as a highly promising target for the development of effective antiviral drugs. Therefore, SARS-CoV-2 3CLpro-IN-1 holds significant potential for advancing research and development in the field of infectious diseases [1].
价 格：￥电议型 号：T63537产 地：中国大陆
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T61774SARS 3CLpro-IN-1；化合物 SARS 3CLpro-IN-1SARS 3CLpro-IN-1
SARS 3CLpro-IN-1 (Compound 3b) is a stereo-specific SARS 3CL protease inhibitor that belongs to the octahydroisochromene scaffold. It demonstrates inhibition against the P1 site imidazole, with an IC50 value of 95 μM [1].
价 格：￥电议型 号：T61774产 地：中国大陆
