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T9177BPAM344Ionotropic glutamate receptors,GluK3a,PAM,iGluR,BPAM344,BPAM 344,Inhibitor,BPAM-344,KAR,GluK1
BPAM344 is a potent positive allosteric modulator (PAM) of the KAR subunits GluK1b, GluK2a, and GluK3a.
价 格:¥电议型 号:T9177产 地:中国大陆
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T7194CM-272DNMT1,anti-tumour,DNMTs,immunogenic,DNA MTases,CM272,DNMT3A,CM 272,G9a,H3K9me2,Inhibitor,epige
CM-272 is a dual G9a/DNA methyltransferases (DNMTs) inhibitor.
价 格:¥电议型 号:T7194产 地:中国大陆
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T64347ALDH1A3-IN-3ALDH1A3IN3
ALDH1A3-IN-3 (compound 16) is a potent inhibitor of ALDH1A3, with an IC50 of 0.26 μM. ALDH1A3-IN-3 is also a good ALDH3A1 substrate. ALDH1A3-IN-3 can be used for the research of prostate cancer.
价 格:¥电议型 号:T64347产 地:中国大陆
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T67758Pumecitinib3Azetidineacetonitrile,3[3amino4(7Hpyrrolo[2,3d]pyrimidin4yl)1Hpyrazol1yl]1[(1methylethyl
Pumecitinib is a Janus kinase (JAK) inhibitor. Pumecitinib exhibits anti-inflammatory activity.
价 格:¥电议型 号:T67758产 地:中国大陆
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T7016VR23Apoptosis,VR-23,VR23,Proteasome,inhibit,Inhibitor,VR 23
VR23 is a potent proteasome inhibitor. Data shows IC50 =1 nM for trypsin-like proteasomes, IC50=50-100 nM for chymotrypsin-like proteasomes, and IC50=3 μM for caspase-like proteasomes.
价 格:¥电议型 号:T7016产 地:中国大陆
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T39707AS-1763AS1763,AS 1763
AS-1763 is an orally available and selective BTK inhibitor with an IC50 of 0.85 nM.
价 格:¥电议型 号:T39707产 地:中国大陆
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T8478SC-43antiproliferative,Inhibitor,SC-43,SHP-1,PTPN6,Phosphatase,Apoptosis,caspase-3,SC 43,anti-fibrot
SC-43 is a potent and orally active agonist of SHP-1 (PTPN6). SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis, and with anti-fibrotic and anticancer effects.
价 格:¥电议型 号:T8478产 地:中国大陆
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T21818Pregnenolone CarbonitrileCYPs,Cytochrome P450,P4503A,orally,Pregnenolone Carbonitrile,Pregnenolone 1
Pregnenolone Carbonitrile is an activator of rodent-PXR and induces the expression of CYP3A.
价 格:¥电议型 号:T21818产 地:中国大陆
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T10436AZD4573AZD 4573,inhibit,CDK,AZD4573,AZD-4573,Inhibitor,Cyclin dependent kinase
AZD4573 is an effective and selective CDK9 inhibitor (IC50: <4 nM). It enables transient target engagement for the treatment of hematologic malignancies.
价 格:¥电议型 号:T10436产 地:中国大陆
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T7774A2793A2793,inhibit,Inhibitor,A-2793,TALK-1,TRESK,pain,KcsA,TASK-1,A 2793,Potassium Channel
A2793 is a chemical compound
价 格:¥电议型 号:T7774产 地:中国大陆
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T38287C3a Receptor Agonist
C3a Receptor Agonist binds the G protein-coupled C3a receptors (C3aRs) in the immune system complement pathway. Activation of C3aR prevents neutrophils from being mobilized in a model of intestinal ischemia-reperfusion injury. C3aRs are expressed on neural progenitor cells and immature neurons in adult mice. C3a stimulates differentiation of neural progenitor cells in vitro.
价 格:¥电议型 号:T38287产 地:中国大陆
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T643631-Pentalenol, 5-hexyl-1,2,3,3a,6,6a-hexahydro-4-phenyl-3a-(1-phenylethenyl)-, (1R,3aS,6aS)-rel-1Pent
1-Pentalenol, 5-hexyl-1,2,3,3a,6,6a-hexahydro-4-phenyl-3a-(1-phenylethenyl)-, (1R,3aS,6aS)-rel- is a potent liver receptor homolog 1 (LRH-1, NR5A2) and steroidogenic factor-1 (SF-1, NR5A1) agonist with pEC 50 s of 6.4 and 7.2, respectively.
价 格:¥电议型 号:T64363产 地:中国大陆
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T6S2246Alisol B 23-acetateInhibitor,inhibit,Alisol B 23 acetate,Alisol B 23acetate,Alisol B 23-acetate
1. Alisol B 23-acetate produces protective effect against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes. 2. Alisol B 23-acetate produces promotive effect on liver regeneration, due to FXR-mediated regulation of genes involved in hepatocyte proliferation and hepato-protection. 3. Alisol B 23-acetate produces a protective effect against CCl4-induced hepatotoxicity, due to FXR and STAT3-mediated gene regulation.
价 格:¥电议型 号:T6S2246产 地:中国大陆
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T7414ARS-853ARS 853,ARS-853,KRAS,Apoptosis,cancer,mutant,state,inhibit,Inhibitor,inactive,Ras,selective,c
ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells
价 格:¥电议型 号:T7414产 地:中国大陆
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T9800Cyclopenta[c][1]benzopyran-8-ol, 1,2,3,3a,4,9b-hexahydro-4-(4-hydroxyphenyl)-, (3aR,4S,9bS)-rel-Cycl
Cyclopenta[c][1]benzopyran-8-ol, 1,2,3,3a,4,9b-hexahydro-4-(4-hydroxyphenyl)-, (3aR,4S,9bS)-rel- is an estrogen receptor beta (ERβ) agonist.
价 格:¥电议型 号:T9800产 地:中国大陆
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T10415Autotaxin-IN-3AutotaxinIN3,Autotaxin IN 3
Autotaxin-IN-3 is an inhibitor of Autotaxin (IC50 = 2.4 nM) which is responsible for the increase in lysophosphatidic acid in ascites and plasma.
价 格:¥电议型 号:T10415产 地:中国大陆
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TQ0094JNJ-40411813ADX71149,JNJ-40411813,ADX 71149,JNJ40411813,mGluR,Inhibitor,JNJ 40411813,Metabotropic gl
JNJ-40411813 (ADX-71149) is a new positive allosteric modulator of the metabotropic glutamate 2 receptor (mGlu2R, EC50: 147 nM).
价 格:¥电议型 号:TQ0094产 地:中国大陆
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T6427ButeinPDE4,Epidermal growth factor receptor,Inhibitor,EGFR,MAPK,ErbB-1,Apoptosis,Autophagy,FoxO3a,in
Butein, a plant polyphenol, is isolated from Rhus verniciflua. It can inhibit the activation of protein tyrosine kinase, NF-κB and STAT3, and also can inhibit EGFR.
价 格:¥电议型 号:T6427产 地:中国大陆
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T7497LC3a 70-77 2TFA(63555-63-5(free base))C3a 70 77 2TFA(63555 63 5(free base)),C3a 7077 2TFA(63555635(fr
C3a 70-77 2TFA is an octapeptide corresponding to the COOH terminus of C3a.
价 格:¥电议型 号:T7497L产 地:中国大陆