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T9041AES-350Histone deacetylases,AES 350,MV4-11,AES-350,Apoptosis,acute myeloid leukemia,AML,Inhibitor,in
AES-350 is a potent and orally active HDAC6 inhibitor(IC50 and a Ki of 0.0244 μM and 0.035 μM, respectively). It is also against HDAC-3, -8, and -11 in an enzymatic activity assay with IC50 values of 0.187 μM, 0.245 μM, and >1μM, respectively. AES-350 triggers apoptosis in AML cells through HDAC inhibition and can be used for acute myeloid leukemia (AML) research.
价 格:¥电议型 号:T9041产 地:中国大陆
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TP1245LACTH 4-11 acetateACTH 4 11 acetate,ACTH 411 acetate
ACTH 4-11 acetate is an adrenocorticotropin hormone fragment and possesses the same amino acid sequence as α-melanocyte stimulating hormone (MSH) does. ACTH 4-11 acetate exhibits a weak MSH potency only at high doses (100 and 1000 nM).
价 格:¥电议型 号:TP1245L产 地:中国大陆
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T9117BSJ-4-116CDK,degrader,antiproliferative,inhibit,Kelly,C1039F,BSJ 4 116,Cyclin dependent kinase,PROTA
BSJ-4-116 is a highly potent and selective CDK12 degrader (PROTAC) with an IC50 of 6 nM. It downregulates DDR genes through a premature termination of transcription, primarily through increasing poly(adenylation).
价 格:¥电议型 号:T9117产 地:中国大陆
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TP1887L1[Ala107]-MBP (104-118) acetate[Ala107]MBP (104118) acetate,[Ala107] MBP (104 118) acetate,[Ala-107]-
[Ala107]-MBP (104-118) acetate is synthetic peptide analog of bovine myelin basic protein (MBP). Non-competitive inhibitor of PKC (IC50 = 46 - 145 mM).
价 格:¥电议型 号:TP1887L1产 地:中国大陆
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TP1888L1[Ala113]-MBP (104-118) acetate[Ala113] MBP (104 118) acetate,[Ala113]MBP (104118) acetate
[Ala113]MBP(104-118) acetate is an noncompetitive peptide inhibitors of protein kinase C (PKC), with IC50s ranging from 28-62 μM.
价 格:¥电议型 号:TP1888L1产 地:中国大陆
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T83496[D-Pro4,D-Trp7,9,10] Substance P (4-11);化合物 [D-Pro4,D-Trp7,9,10] Substance P (4-11)[D-Pro4,D-Trp7,9,
[D-Pro4,D-Trp7,9,10] Substance P (4-11) serves as a potent antagonist of the tachykinin family of neuropeptides [1].
价 格:¥电议型 号:T83496产 地:中国大陆
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T83495[D-Pro4,D-Trp7,9] Substance P (4-11);化合物 [D-Pro4,D-Trp7,9] Substance P (4-11)[D-Pro4,D-Trp7,9] Subst
[D-Pro4,D-Trp7,9] Substance P (4-11) acts as a potent antagonist to Substance P, significantly reducing plasma aldosterone (ALDO) concentrations[1].
价 格:¥电议型 号:T83495产 地:中国大陆
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T81663NN1177;化合物 NN1177NNC9204-1177;NNC9204-1177
NN1177, a long-acting GLP-1/glucagon receptor co-agonist, exhibits a dose-dependent reduction in body weight among diet-induced obese (DIO) mice and has potential applications in the study of weight loss and metabolic regulation [1].
价 格:¥电议型 号:T81663产 地:中国大陆
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T80135Tyr-(D-Dab4,Arg5,D-Trp8)-cyclo-Somatostatin-14 (4-11);化合物 Tyr-(D-Dab4,Arg5,D-Trp8)-cyclo-Somatostati
Tyr-(D-Dab4,Arg5,D-Trp8)-cyclo-Somatostatin-14 (4-11) is a somatostatin agonist utilized in cancer research [1].
价 格:¥电议型 号:T80135产 地:中国大陆
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T76483[Sar4] Substance P (4-11);化合物 [Sar4] Substance P (4-11)[Sar4] Substance P (4-11)
[Sar4] Substance P (4-11) is a Substance P agonist and an analog of the C-terminus fragment of Substance P, known as Substance P (4-11) [1].
价 格:¥电议型 号:T76483产 地:中国大陆
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T76455Substance P (4-11);化合物 Substance P (4-11)Substance P (4-11)
Substance P (4-11), a C-terminal fragment of Substance P, acts as a highly selective agonist for NK1 receptors, demonstrating specificity in its interaction.
价 格:¥电议型 号:T76455产 地:中国大陆
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T76447[DAla4] Substance P (4-11);化合物 [DAla4] Substance P (4-11)[DAla4] Substance P (4-11)
[DAla4] Substance P (4-11), an analog of Substance P (Substance P), effectively inhibits the binding of 125I-Bolton Hunter-conjugated Eledoisin (Eledoisin) and 125I-Bolton Hunter-conjugated Substance P to rat brain cortex membranes, with IC50 values of 0.5 μM and 0.15 μM, respectively [1].
价 格:¥电议型 号:T76447产 地:中国大陆
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T76406[D-Pro4,D-Trp7,9,Nle11] Substance P (4-11);化合物 [D-Pro4,D-Trp7,9,Nle11] Substance P (4-11)[D-Pro4,D-T
[D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) is a potent neurokinin NK1 antagonist that effectively inhibits the actions of gold-protein-substance P (GPSP) and substance P (SP), demonstrating its efficacy in neutralizing their effects [1].
价 格:¥电议型 号:T76406产 地:中国大陆
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T75887[Ala113]MBP(104-118) TFA;化合物 [Ala113]MBP(104-118) TFA[Ala113]MBP(104-118) TFA
[Ala113]MBP(104-118) TFA is a peptide inhibitor operating noncompetitively against protein kinase C (PKC), exhibiting inhibitory concentrations (IC50) in the range of 28-62 μM [1].
价 格:¥电议型 号:T75887产 地:中国大陆
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T75886[Ala107]MBP(104-118) TFA;化合物 [Ala107]MBP(104-118) TFA[Ala107]MBP(104-118) TFA
[Ala107]MBP(104-118) TFA is a noncompetitive peptide inhibitor of protein kinase C (PKC), exhibiting IC50 values between 46-145 μM.
价 格:¥电议型 号:T75886产 地:中国大陆
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T72979LEM-14-1189;化合物LEM-14-1189LEM-14-1189
Lem-14-1189, a LEM-14 derivative, is a potent NSD inhibitor of the nuclear receptor binding SET domain, and has inhibitory effects on NSD1, NSD2, and NSD3, with IC50 of 418 μM, 111 μM, and 60 μM, respectively. LEM-14-1189 has potential anticancer activity and can be used to study multiple myeloma (MM) and diseases of the blood system.
价 格:¥电议型 号:T72979产 地:中国大陆
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T32134Icopezil maleate;化合物 T32134CP 118954-11|||CP-118,954-11;CP 118954-11|||CP-118,954-11
Icopezil maleate is a bio-active chemical.
价 格:¥电议型 号:T32134产 地:中国大陆
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T27636Ispronicline;异丙克兰AZD-3480|||RJR-1734|||AZD 3480|||TC 1734|||AZD3480|||TC-01734|||TC-1734-112;AZD-348
Ispronicline (TC-1734) An orally active, selective, and potent α4β2 nAChR partial agonist with antidepressant, neuroprotective, and long-lasting cognitive effects.Ispronicline has a high affinity for the α4β2 nAChR with a Ki= 11 nM.
价 格:¥电议型 号:T27636产 地:中国大陆
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T24901Troponin I (104-115);化合物 T24901Ac-Gly-lys-phe-lys-arg-pro-pro-leu-arg-arg-val-arg-NH2|||Tni peptide
Troponin I is a cardiac and skeletal muscle protein useful in the laboratory diagnosis of a heart attack. Troponin I is a part of the troponin protein complex, where it binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place.
价 格:¥电议型 号:T24901产 地:中国大陆