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T4687Ro5-3335CBFβ-Runx1 inhibitor II；Ro 5-3335
Ro 5-3335 is core binding factor (CBF) inhibitor; preferentially kills human leukemia cell lines with CBF fusion proteins (IC50 = 1.1 μM). It represses RUNX1/CBFβ-dependent transactivation in reporter assays and inhibits transcriptional regulation by RUNX
价 格：￥电议型 号：T4687产 地：中国大陆
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T4687Ro 5-3335Ro 5-3335,CBFβ-Runx1 inhibitor II,
Ro 5-3335 is core binding factor (CBF) inhibitor; preferentially kills human leukemia cell lines with CBF fusion proteins (IC50 = 1.1 μM). It represses RUNX1/CBFβ-dependent transactivation in reporter assays and inhibits transcriptional regulation by RUNX
价 格：￥电议型 号：T4687产 地：美洲
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T4687Ro5-3335；化合物Ro 5-3335CBFβ-Runx1 inhibitor II|||Ro 5-3335；CBFβ-Runx1 inhibitor II|||Ro 5-3335
Ro5-3335 (CBFβ-Runx1 inhibitor II) is core binding factor (CBF) inhibitor; preferentially kills human leukemia cell lines with CBF fusion proteins (IC50 = 1.1 μM). Ro5-3335 represses RUNX1/CBFβ-dependent transactivation in reporter assays and inhibits transcriptional regulation by RUNX1 and CBFβ. Ro5-3335 also reduces the leukemia burden in a mouse model. Attenuates RUNX1-dependent hematopoiesis in zebrafish embryos. It also is a Tat antagonist and inhibits HIV-1 replication in vitro.
价 格：￥电议型 号：T4687产 地：中国大陆
