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TN2330Phenethyl ferulatePhenethyl ferulate,Lipoxygenase,5-LOX,Cyclooxygenase,Inhibitor,5-lipoxygenase,inhi
Caffeic Acid 3-Methyl Phenethyl Ester has chemopreventive properties against chemically induced colon carcinogenesis. It enhances apoptosis in azoxymethane induced colon tumors. It shows inhibitory activity against cyclooxygenase (COX) and 5-lipoxygenase (5-LOX) with IC50 values of 4.35 μM and 5.75 μM, respectively.
价 格:¥电议型 号:TN2330产 地:中国大陆
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T6893MK-886leukotriene,FLAP,5-LOX,5-LO activating protein,non-competitive,L-663536,L663536,keratin-1,Leuk
MK-886 is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP). It is also a moderately potent PPARα antagonist.
价 格:¥电议型 号:T6893产 地:中国大陆
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T8356FPL 62064Cyclooxygenase,FPL 62064,LOX,5-lipoxygenase,FPL62064,inhibit,FPL-62064,Prostaglandin,5-LOX,
FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and COX (IC50 of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and prostaglandin synthetase, respectively).
价 格:¥电议型 号:T8356产 地:中国大陆
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T6S0413PectolinarigeninCOX,Cyclooxygenase,Lipoxygenase,melanogenesis,anti-inflammation,5-LOX,COX-2,inhibit,
1. Pectolinarigenin exhibits hepatoprotective activity mainly via SOD antioxidant mechanism. 2. Pectolinarigenin possesses anti-inflammatory activity and that they may inhibit eicosanoid formation in inflammatory lesions.
价 格:¥电议型 号:T6S0413产 地:中国大陆
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T79362COX-2/15-LOX-IN-4;化合物 COX-2/15-LOX-IN-4COX-2/15-LOX-IN-4
COX-2/15-LOX-IN-4 (compound 5i) is a dual inhibitor with IC50 values of 0.075 μM for COX-2 and 1.97 μM for 15-LOX. It inhibits LPS-induced production of pro-inflammatory cytokines (IL-6, ROS) and exhibits targeted anti-inflammatory effects [1].
价 格:¥电议型 号:T79362产 地:中国大陆
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T79361COX-2/15-LOX-IN-3;化合物 COX-2/15-LOX-IN-3COX-2/15-LOX-IN-3
COX-2/15-LOX-IN-3 (compound 5k) serves as a dual inhibitor for COX-2 and 15-LOX, demonstrating inhibitory concentrations (IC50) of 0.075 μM and 1.97 μM, respectively. This compound effectively suppresses LPS-induced cellular production of pro-inflammatory cytokines (IL-6, ROS, and NO), exhibiting targeted anti-inflammatory effects [1].
价 格:¥电议型 号:T79361产 地:中国大陆
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T79360COX-2/15-LOX-IN-2;化合物 COX-2/15-LOX-IN-2COX-2/15-LOX-IN-2
COX-2/15-LOX-IN-2 is a potent inhibitor of both COX-2 and 15-LOX, demonstrating IC50 values of 0.065 μM for COX-2 and 1.86 μM for 15-LOX. Additionally, it exhibits significant antioxidant activity [1].
价 格:¥电议型 号:T79360产 地:中国大陆
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T79158h15-LOX-2 inhibitor 1;化合物 h15-LOX-2 inhibitor 1h15-LOX-2 inhibitor 1
Compound 105 (h15-LOX-2 inhibitor 1) is a potent inhibitor of human epithelial 15-lipoxygenase-2 (h15-LOX-2), exhibiting an IC50 of 0.34 μM [1].
价 格:¥电议型 号:T79158产 地:中国大陆
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T788205-LOX-IN-5;化合物 5-LOX-IN-55-LOX-IN-5
Compound 29, also known as 5-LOX-IN-5, is a 5-lipoxygenase (5-LOX) inhibitor with an inhibitory concentration 50 (IC50) of 56 nM, utilized in research pertaining to neurodegenerative diseases [1].
价 格:¥电议型 号:T78820产 地:中国大陆
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T775285-LOX-IN-2;5-LOX抑制剂25-LOX-IN-2
5-LOx-in-2 is a 5-lipoxygenase inhibitor (5-LOX) with an IC50 value of 0.33 μM. 5-lox-in-2 inhibits 5-LOX action IN a dose-dependent manner. 5-LOX-IN-2 can reduce the cell activity of kidney cancer cells and induce apoptosis, and can be used in cancer research.
价 格:¥电议型 号:T77528产 地:中国大陆
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T654275-LOX inhibitor;5-LOX 抑制剂1-(sec-Butyl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-tria
5-LOX inhibitor (1-(sec-Butyl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one) is one of the impurities of itraconazole, a selective LOX-5 inhibitor.
价 格:¥电议型 号:T65427产 地:中国大陆
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T62998COX-2/15-LOX-IN-1;化合物 COX-2/15-LOX-IN-1COX-2/15-LOX-IN-1
COX-2/15-LOX-IN-1 (Compound 14) is a COX-2 and 15-lipoxygenase (15-LOX) inhibitor that acts on COX-1 (IC50: 10.65 μM), COX-2 (IC50: 0.075 μM) and 15-LOX (IC50: 2.98 μM). 25 has an anti-inflammatory effect.
价 格:¥电议型 号:T62998产 地:中国大陆
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T61910COX-2/5-LOX-IN-2;化合物 COX-2/5-LOX-IN-2COX-2/5-LOX-IN-2
COX-2/5-LOX-IN-2 is a benzothiophen-2-ylpyrazole carboxylic acid derivative. COX-2/5-LOX-IN-2 (5b) inhibited both COX-2 and 5-LOX. The IC50s of COX-2/5-LOX-IN-2 inhibiting COX-1, COX-2 and 5-LOX were 5.40, 0.01 and 1.78 μM, respectively. COX-2/5-LOX-IN-2 showed more analgesic and anti-inflammatory activities than Celecoxib and Indomethacin.
价 格:¥电议型 号:T61910产 地:中国大陆
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T61674COX-2/5-LOX-IN-1;化合物 COX-2/5-LOX-IN-1COX-2/5-LOX-IN-1
COX-2/5-LOX-IN-1 (compound 3a), a benzothiophen-2-yl pyrazole carboxylic acid derivative, is a potent and dual inhibitor of COX-2 / 5-LOX. It exhibits superior analgesic and anti-inflammatory properties compared to Celecoxib and Indomethacin. COX-2/5-LOX-IN-1 displays strong inhibitory activity against COX-1, COX-2, and 5-LOX, with IC50 values of 12.13 μM, 0.4 μM, and 4.96 μM, respectively [1].
价 格:¥电议型 号:T61674产 地:中国大陆
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T61352COX-2/5-LOX-IN-3;化合物 COX-2/5-LOX-IN-3COX-2/5-LOX-IN-3
COX-2/5-LOX-IN-3 (compound 5b) is a powerful and dual inhibitor of COX-2 and 5-LOX, with IC50 values of 45.73 μM, 5.45 μM, and 4.33 μM for COX-1, COX-2, and 5-LOX, respectively. This compound, COX-2/5-LOX-IN-3, shows promise for the investigation of inflammatory diseases [1].
价 格:¥电议型 号:T61352产 地:中国大陆
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T612115-LOX-IN-1;化合物5-LOX-IN-15-LOX-IN-1
5-LOX-IN-1 is a 5-Lipoxygenase (5-LOX) inhibitor (IC50: 2.3 μM).5-LOX-IN-1 can be used for cancer research.
价 格:¥电议型 号:T61211产 地:中国大陆
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T60630COX/5-LOX-IN-1;化合物 COX/5-LOX-IN-1COX/5-LOX-IN-1
COX/5-LOX-IN-1 (compound 6b) is a potent COX/5-LOX dual inhibitor with the potential for inflammation diseases research. COX/5-LOX-IN-1 has IC50s of 1.07, 0.55, and 0.28 μM for COX-1, COX-2, and 5-LOX enzyme, respectively [1].
价 格:¥电议型 号:T60630产 地:中国大陆
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T3616915-LOX-1 inhibitor 19c(i472)15 LOX 1 inhibitor 1|||15LOX1 inhibitor 1
9c(i472) is an inhibitor of 15-lipoxygenase-1 (15-LO-1; IC50 = 0.19 μM).1 It decreases LPS- and IFN-γ-induced NF- B activity in RAW-Blue cells when used at concentrations of 0.2, 1, and 5 μM. 9c(i472) reduces LPS- and IFN-γ-induced increases in Nos2 expression and lipid peroxidation in RAW 264.7 cells when used at a concentration of 5 μM.
价 格:¥电议型 号:T36169产 地:中国大陆