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T61518TAK-653
TAK-653, an AMPA receptor potentiator with minimal agonistic activity, produces an antidepressant-like effect with a favorable safety profile in rats.
价 格:¥电议型 号:T61518产 地:中国大陆
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T74512-Cyanopyrimidineinhibit,Cathepsin,protease,2-Cyanopyrimidine,cysteine,2Cyanopyrimidine,osteoporos,2
2-cyano-Pyrimidine is inhibitor of cathepsin K(IC50 : 170 nM)
价 格:¥电议型 号:T7451产 地:中国大陆
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TN1519L(-)-Coclaurine hydrochloride
(-)-Coclaurine hydrochloride is an antagonist of nAChRs isolated from Sarcopetalum harveyanum.
价 格:¥电议型 号:TN1519L产 地:中国大陆
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T24040ERDRP-0519
ERDRP-0519, an orally bioavailable small-molecule Measles virus (MeV) polymerase inhibitor, prevents measles disease in squirrel monkeys (Saimiri sciureus). ERDRP-0519 inhibits morbilliviruses with nanomolar potency.
价 格:¥电议型 号:T24040产 地:中国大陆
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T64351GI-560192
GI-560192 is a potent smo cilial modulator with an EC50 value of 0.02 ?M. GI-560192 modulates the translocation and/or accumulation of smoothened to the primary cilia by hedgehog signaling pathway.
价 格:¥电议型 号:T64351产 地:中国大陆
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T6451Clodronic acid disodium saltClodronic acid disodium,inhibit,ADP,mitochondria,first-generation,metast
Clodronate Disodium, a bisphosphonate, is a potent antiosteolytic agent which inhibits bone resorption.
价 格:¥电议型 号:T6451产 地:中国大陆
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T14681BMS-935177BMS 935177,BMS935177
BMS-935177 is a reversible BTK inhibitor with IC50 value of 3 nM.
价 格:¥电议型 号:T14681产 地:中国大陆
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TN1516CnidicinCnidicin,Inhibitor,inhibit
Cnidicin has anti-allergic and anti-inflammatory activity, it inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells(IC50 value, 7.5 microM). Cnidicin exhibits a significant inhibition on the proliferation of cultured human tumor cells such as A549 (non small cell lung), SK-OV-3 (ovary), SK-MEL-2 (melanoma), XF498 (central nervous system) and HCT-15 (colon) in vitro .
价 格:¥电议型 号:TN1516产 地:中国大陆
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T9519EliapixantInhibitor,chronic,Eliapixant,cough,refractory,BAY-1817080,P2X Receptor,BAY1817080,P2X3,inh
Eliapixant (BAY 1817080) is a potent and selective P2X3 receptor antagonist, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough.
价 格:¥电议型 号:T9519产 地:中国大陆
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T6885MarimastatTA-2516,Marimastat,inhibit,Inhibitor,BB 2516,BB-2516,TA 2516,Matrix metalloproteinases,MMP
Marimastat (BB-2516) is a potent, broad spectrum matrix metalloprotease (MMP) inhibitor. MMP-9 (IC50=3 nM), MMP-1 (IC50=5 nM), MMP-2 (IC50=6 nM), MMP-14 (IC50=9 nM)and MMP-7 (IC50=13 nM).
价 格:¥电议型 号:T6885产 地:中国大陆
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T2518ARRY-380 (analog )Inhibitor,HER1,EGFR,ARRY380 (analog ),Epidermal growth factor receptor,ARRY 380 (a
ARRY-380 is a potent and selective HER2 inhibitor.
价 格:¥电议型 号:T2518产 地:中国大陆
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T7509PD 117519CI-947,PD-117519,Adenosine Receptor,Inhibitor,P1 receptor,PD117519,PD 117519,inhibit,CI 947
PD 117519 is an agonist of adenosine receptor
价 格:¥电议型 号:T7509产 地:中国大陆
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TMO268510-Hydroxydecanoic Acid10Hydroxydecanoic Acid,NSC15139,NSC-15139,10-Hydroxydecanoic acid,inhibit,Inh
It has antibacterial, anti - cancer and anti - radiation activity.
价 格:¥电议型 号:TMO2685产 地:中国大陆
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T6068MK-5108MK 5108,VX689,Aurora Kinase,VX 689,inhibit,Autophagy,MK-5108,Inhibitor
MK-5108 is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value of 0.064 nM.
价 格:¥电议型 号:T6068产 地:中国大陆
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T8873BractoppinDNA break,Bractoppin,phosphopeptide,inhibit,DNA/RNA Synthesis,DNA damage,RAD51,G2 arrest,I
Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibits substrate binding with nanomolar potency in vitro. Structure-activity exploration suggests that Bractoppin engages BRCA1 tBRCT residues recognizing pSer in the consensus motif, pSer-Pro-Thr-Phe, plus an abutting hydrophobic pocket that is distinct in structurally related BRCT domains, conferring selectivity.
价 格:¥电议型 号:T8873产 地:中国大陆
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TP1290GRGDSP acetate(91037-75-1 free base)GRGDSP acetate(91037 75 1 free base),GRGDSP acetate(91037751 fre
GRGDSP acetate is a synthetic linear RGD peptide and is an integrin inhibitor.
价 格:¥电议型 号:TP1290产 地:中国大陆
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T73513-Methylcytidineinhibit,3-Methylcytidine,Inhibitor,3Methylcytidine,Nucleoside Antimetabolite/Analog,
3-Methylcytidine as biomarkers of four different types of cancer: lung cancer, gastric cancer, colon cancer, and breast cancer.
价 格:¥电议型 号:T7351产 地:中国大陆
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T25192Butyrolactone I
Butyrolactone I is an ATP-competitive inhibitor of CDK and cdc2 kinase family. Butyrolactone I shows antitumor effects in non-small cell lung, small cell lung, and prostate cancer cell lines.
价 格:¥电议型 号:T25192产 地:中国大陆
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T10852CNS-5161 hydrochloride
CNS-5161 hydrochloride is a new antagonist of NMDA ion-channel. It interacts with the NMDA receptor/ion channel site to produce a noncompetitive blockade of the actions of glutamate.
价 格:¥电议型 号:T10852产 地:中国大陆
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TP1851LScyliorhinin II acetateScyliorhinin II acetate
Scyliorhinin II acetate is a selective agonist of the neurokinin-3 (NK3) receptor (Ki = 2.5 nM) in rat cerebral cortex.
价 格:¥电议型 号:TP1851L产 地:中国大陆