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T9019JHU37152JHU37152,inhibit,hM3Dq,Clozapine,Inhibitor,DREADD,Muscarinic acetylcholine receptor,mAChR,hM
JHU 37152 is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist with Ki of 1.8 nM and 8.7 nM for human muscarinic acetylcholine M3 receptors (hM3Dq) and hM4Di in vitro, respectively. And EC50 values are 5 nM and 0.5 nM for hM3Dq and hM4Di in fluorescent and BRET-based assays in HEK-293 cells, respectively.
价 格:¥电议型 号:T9019产 地:中国大陆
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T7152Ravuconazoleinhibit,ER30346,BMS207147,Ravuconazole,BMS 207147,Fungal,ER 30346,Inhibitor
Ravuconazole is a potent triazole antifungal that potently inhibits a wide range of fungi.
价 格:¥电议型 号:T7152产 地:中国大陆
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T77152Crenezumab;化合物 CrenezumabCrenezumab
Crenezumab (MABT 5102A; RG 7412), a fully humanized monoclonal antibody targeting Aβ, exhibits binding affinity for various forms of Aβ, including soluble, oligomeric, and fibrillar. It is utilized in the study of Alzheimer´s disease [1].
价 格:¥电议型 号:T77152产 地:中国大陆
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T71529NO 794;化合物 NO 794NO 794
NO 794 is a histamine H2-receptor antagonist.
价 格:¥电议型 号:T71529产 地:中国大陆
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T71528MCN-5908;化合物 MCN-5908MCN-5908
MCN-5908 is a dopamine uptake inhibitor.
价 格:¥电议型 号:T71528产 地:中国大陆
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T71527NSC145366;化合物 NSC145366NSC145366
NSC145366 is an inhibitor of Hsp90 activities which targets the Hsp90 C-terminal domain to induce allosteric inhibition and selective client downregulation. NSC145366 increases Hsp90 oligomerization resulting in allosteric inhibition of NTD ATPase activity (IC50=119μM) but does not compete with NTD or CTD-ATP binding.
价 格:¥电议型 号:T71527产 地:中国大陆
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T71526CH5164840;化合物 CH5164840CH5164840
CH5164840 is a potent and selective HSP90 inhibitor. CH5164840 showed remarkable antitumor activity against NSCLC cell lines and xenograft models. CH5164840 has potent antitumor activity and is highly effective in combination with erlotinib against NSCLC tumors with EGFR overexpression and mutations.
价 格:¥电议型 号:T71526产 地:中国大陆
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T71525AB05831;化合物 AB05831AB05831
AB05831, also known as 2-Acetamido-1,2-dideoxynojirimycin, is a highly potent and specific inhibitor of beta-hexosaminidase. N-Acetyl-3-hexosaminidase (HEX) is a member of lysosomal hydrolases, which catalyzes hydrolysis of terminal, non-reducing N-acetyl-|3-D-glucosamine (GlcNAc) andN-acetyl-(3-D-galactosamine (GalNAc) residues in glycoproteins, gan-gliosides, and glycosaminoglycans (GAGs). HEX, released by chondrocytes into the extracellular compartment, promotes cartilage matrix degradation.
价 格:¥电议型 号:T71525产 地:中国大陆
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T71524Famiraprinium;化合物 FamirapriniumFamiraprinium
Famiraprinium is a competitive antagonist at the GABA receptor site.
价 格:¥电议型 号:T71524产 地:中国大陆
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T71523Norbinaltorphimine;化合物 nor-Binaltorphimine dihydrochlorideNorbinaltorphimine
nor-Binaltorphimine dihydrochloride is a long-acting potent and highly selective kappa opioid receptor antagonist.
价 格:¥电议型 号:T71523产 地:中国大陆
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T71522FLM-5011;化合物 FLM-5011FLM-5011
FLM-5011 is a a lipoxygenase inhibitor with anti-inflammatory effects.
价 格:¥电议型 号:T71522产 地:中国大陆
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T71521NK-611 free acid;化合物 NK-611 free acidNK-611 free acid
NK-611 free acid is a new semisynthetic analogue of etoposide, which presumably also acts through inhibition of topoisomerase II, and has been found to be more potent against several cancer cell lines in vitro than etoposide.
价 格:¥电议型 号:T71521产 地:中国大陆
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T71520LEQ-506;化合物 LEQ-506LEQ-506
LEQ506, also known as NPV-LEQ506, is an orally bioavailable small-molecule Smoothened (Smo) antagonist with potential antineoplastic activity. Smoothened antagonist LEQ506 selectively binds to the Hedgehog (Hh)-ligand cell surface receptor Smo, which may result in the suppression of the Hh signaling pathway, thereby inhibiting tumor cell growth.
价 格:¥电议型 号:T71520产 地:中国大陆
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T7152Ravuconazole;雷夫康唑BMS-207147|||ER-30346;立福康唑|||雷夫康唑|||BMS-207147|||ER-30346
Ravuconazole (ER-30346) is a potent triazole antifungal that potently inhibits a wide range of fungi.
价 格:¥电议型 号:T7152产 地:中国大陆
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T67152Dacomitinib Intermediate 2;达可替尼中间体2N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine;N
Dacomitinib Intermediate 2 (N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine) has anticancer activity and can be used to study lung cancer.
价 格:¥电议型 号:T67152产 地:中国大陆
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T371523-Methyl-2-cyclopenten-1-one;3-甲基-2-环戊烯-1-酮3-Methyl-2-cyclopenten-1-one
3-Methyl-2-cyclopenten-1-one can be used as a food additive to improve the flavor of meat and meat products at 2-5 ppm. Addition of 3-Methyl-2-cyclopenten-1-one showed gastric cytoprotective activity when administered orally to male Wistar rats.
价 格:¥电议型 号:T37152产 地:中国大陆
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T33748NSC 77152;化合物 T33748NSC77152|||NSC-77152;NSC77152|||NSC-77152
NSC 77152 is a bioactive chemical.
价 格:¥电议型 号:T33748产 地:中国大陆
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T28529RG 7152;化合物 RG 7152RG7152|||RG-7152;RG7152|||RG-7152
RG 7152 is a leukotriene D4 antagonist with anti-asthmatic properties and can be used in the study of asthma.
价 格:¥电议型 号:T28529产 地:中国大陆
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T27152Dexamethasone Beloxil;化合物 T27152Dexamethasone Beloxil
Dexamethasone Beloxil is a glucocorticoid, Anti-inflammatory Agent.
价 格:¥电议型 号:T27152产 地:中国大陆
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T20381Cetyl glycol;1,2-十六烷二醇NSC-71525|||NSC 71525|||NSC71525;NSC-71525|||NSC 71525|||1,2-十六烷二醇|||NSC71525
Cetyl glycol (NSC-71525) favors the decomposition of the metal-organic precursor, formation of an intermediate Co(2+)Fe(3+)-oleate complex, and the nucleation of nanoparticles at lower temperatures. Cetyl glycol is a reducing agent that can be used in cosmetics.
价 格:¥电议型 号:T20381产 地:中国大陆