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  • T378038-bromo-Cyclic ADP-Ribose (sodium salt);8-bromo-Cyclic ADP-Ribose (sodium salt)8-bromo-Cyclic ADP-Ri

    Cyclic ADP-ribose (cADP-ribose) is a calcium mobilizing nucleotide that is biosynthesized from NAD+ by cADP-ribose synthases, including CD38. cADP-Ribose appears to activate calcium channels in intracellular membranes, which in turn activate ryanodine receptors. 8-bromo-cADP-Ribose is a stable, cell-permeable analog that blocks calcium release evoked by cADP-ribose in sea urchin egg homogenates with an IC50 value of 1.7 μM. It is commonly used to investigate intracellular signaling through cADP-

    价 格:¥电议型 号:T37803产 地:中国大陆

  • T36677Rp-8-bromo-Cyclic AMPS (sodium salt);Rp-8-bromo-Cyclic AMPS (sodium salt)Rp-8-bromo-Cyclic AMPS (sod

    Rp-8-bromo-Cyclic AMPS (Rp-8-bromo-cAMPS) is a cell-permeable cAMP analog that combines an exocyclic sulfur substitution in the equatorial position of the cyclophosphate ring with a bromine substitution in the adenine base of cAMP. It acts as an antagonist of cAMP-dependent protein kinases (PKAs) and is resistant to hydrolysis by cyclic nucleotide phosphodiesterases. Rp-8-bromo-cAMPS more effectively antagonizes cAMP-dependent activation of purified PKA type I from rabbit muscle than PKA type II

    价 格:¥电议型 号:T36677产 地:中国大陆

  • T354248-bromo-Cyclic AMP;8-bromo-Cyclic AMP8-bromo-Cyclic AMP

    8-bromo-Cyclic AMP is a brominated derivative of cAMP that remains long-acting due to its resistance to degradation by cAMP phosphodiesterase. It can activate cAMP-dependent protein kinase, inhibiting growth, decreasing proliferation, increasing differentiation, and inducing apoptosis of cancer cells.

    价 格:¥电议型 号:T35424产 地:中国大陆

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