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T67698WAY-300374WAY300374
WAY-300374 inhibits the p53-MDM2 protein-protein interaction.
价 格:¥电议型 号:T67698产 地:中国大陆
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TP1559LZiconotide Acetate (107452-89-1 free base)analgesic,non-opioid,Ziconotide Acetate (107452891 free
Ziconotide is an analgesic agent and has been used to treat neuropathic and non-neuropathic pain. Ziconotide acts by binding to N-type calcium channels situated on the terminal part of primary afferent neurons of the nociceptive pathway therefore reducing synaptic transmission with potent antinociceptive effects.
价 格:¥电议型 号:TP1559L产 地:中国大陆
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T8439Clobenpropit dihydrobromideApoptosis,inhibit,Clobenpropit dihydrobromide,histamine H3R,antagonist,in
Clobenpropit dihydrobromide is a potent antagonist and inverse agonist of histamine H3R (histamine H3LR,pEC50 of 8.07)
价 格:¥电议型 号:T8439产 地:中国大陆
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T9840AtaquimasAtaquimas
Ataquimast inhibits IL-5 secretion along with that of TNF-a, IL-4 and GM-CSF from human cells.
价 格:¥电议型 号:T9840产 地:中国大陆
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T16940STAT5-IN-2STAT-5-IN-2,STAT5IN2,STAT5 IN 2
STAT5-IN-2 is an inhibitor of STAT5 with antileukemic effects (EC50s: 9 μM and 5 μM in K562 and KU812 cells, respectively).
价 格:¥电议型 号:T16940产 地:中国大陆
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TN12955-O-Caffeoylshikimic acidinhibit,5 O Caffeoylshikimic acid,Inhibitor,5OCaffeoylshikimic acid
5-O-Caffeoylshikimic acid shows anti-oxidative activity; it also shows anti-inflammatory activity, the underlying mechanism was associated with downregulation of nuclear factor-κB.
价 格:¥电议型 号:TN1295产 地:中国大陆
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TP1881L1Pep 2-8 ammonium salt(1541011-97-5 free base)Pep 2 8 ammonium salt(1541011 97 5 free base),Pep 28 am
Pep 2-8 ammonium salt is Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. Potent inhibitor of PCSK9 binding to LDL receptor (IC50 = 0.8 μM). Restores LDL uptake in HepG2 cells treated with PCSK9.
价 格:¥电议型 号:TP1881L1产 地:中国大陆
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T22849ICI 199,441 hydrochlorideICI 199,441 hydrochloride
ICI 199,441 hydrochloride is a potent, selective agonist of κ-opioid receptor.
价 格:¥电议型 号:T22849产 地:中国大陆
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TP1789LMalantide acetate(86555-35-3 free base)Malantide acetate(86555 35 3 free base),Malantide acetate(865
Malantide acetate is a dodecapeptide phosphorylated by cyclic AMP-dependent protein kinase (PKA), and increases PKA activity.Malantide is a synthetic peptide that is phosphorylated by PKA and is used to measure PKA activity in vitro.
价 格:¥电议型 号:TP1789L产 地:中国大陆
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T23128PD180970PD-180970,PD180970
PD180970 is an inhibitor of Bcr-Abl with IC50s of 5 nM, 0.8 nM and 50 nM for the autophosphorylation of p210Bcr-Abl, Src and Kit. PD180970 can be used in studies about chronic myelogenous leukemia.
价 格:¥电议型 号:T23128产 地:中国大陆
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T61392NLRP3-IN-10
NLRP3-IN-10 is a potent NLRP3 inhibitor. NLRP3-IN-10 inhibits IL-1β release with an IC50 value of 251.1 nM. NLRP3-IN-10 attenuates ASC speck formation, leading to suppress activation of NLRP3 inflammasome.
价 格:¥电议型 号:T61392产 地:中国大陆
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T9192BIIB068ADME,inhibit,FcγR,Autoimmune,Bruton tyrosine kinase,TNFα,BIIB 068,ROS,Inhibitor,reversible,Bt
BIIB068 is an selective, reversible and orally active BTK inhibitor (IC50 = 1 nM, Kd = 0.3 nM). BIIB068 is 400 times more selective for BTK than other kinases.
价 格:¥电议型 号:T9192产 地:中国大陆
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TP1898HS024selective,melanocortin,intake,Inhibitor,Melanocortin Receptor,MC Receptor,HS-024,food,HS024,inh
Highly potent melanocortin MC4 receptor antagonist (Ki values are 0.29, 18.6, 5.45 and 3.29 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake, and blocks α-MSH- and MTII-induced hypotension and bradycardia in rats, following central administration in vivo.
价 格:¥电议型 号:TP1898产 地:中国大陆
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T9645CU-115
CU-115 is a selective and potent TLR8 antagonist with IC50 of 1.04 ?M and =>50 ?M for TLR8 and TLR7, respectively. CU-115 decreases production of TNF-α and IL-1β activated by R-848 in THP-1 cells.
价 格:¥电议型 号:T9645产 地:中国大陆
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T67749Fuzapladib
Fuzapladib (IS-741) is a phospholipase A2 inhibitor that can inhibits the expression of Mac-1, a cell adhesion molecule. Fuzapladib blocks activation of adhesion molecules (integrin) expressed on the inflammatory cell surface to prevent inflammatory cells from adhering to vascular endothelial cells and infiltrating tissue and to control exacerbation of pancreatitis.
价 格:¥电议型 号:T67749产 地:中国大陆
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TN2079(-)-Pinoresinol()Pinoresinol,( ) Pinoresinol
(-)-Pinoresinol is isolated from the whole plant of Serissa japonica (Thunb.) Thunb.
价 格:¥电议型 号:TN2079产 地:中国大陆
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T9268UlinastatinUlinastatin
Ulinastatin is a multivalent Kunitz-type serine protease inhibitor with anti-inflammatory properties.
价 格:¥电议型 号:T9268产 地:中国大陆
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TP1882L1Orphanin FQ(1-11) acetate(178249-41-7 free base)Orphanin FQ(1 11) acetate(178249 41 7 free base),Orp
Peptide fragment containing amino acids 1-11 of Nociceptin. Potent agonist of the ORL1/KOR-3 receptor (Ki = 55 nM); displays no affinity for opioid receptors, including μ, δ, κ1 and κ3 receptors (Ki >1000 nM). Displays analgesic properties in CD-1 mice.
价 格:¥电议型 号:TP1882L1产 地:中国大陆
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T9743FEN1-IN-SC13FEN1 IN SC13,Inhibitor,FEN1INSC13,FEN-1-IN-SC13,inhibit
FEN1-IN-SC13 is a potent inhibitor of DNA fragmentation endonuclease 1 (FEN1)
价 格:¥电议型 号:T9743产 地:中国大陆
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T8595Practololreceptor,inhibit,arrhythmias,β1-adrenergic,Practolol,Beta Receptor,Adrenergic Receptor,card
Practolol is a selective β-adrenoceptor blocker.
价 格:¥电议型 号:T8595产 地:中国大陆