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TP1559LZiconotide Acetate (107452-89-1 free base)analgesic,non-opioid,Ziconotide Acetate (107452891 free
Ziconotide is an analgesic agent and has been used to treat neuropathic and non-neuropathic pain. Ziconotide acts by binding to N-type calcium channels situated on the terminal part of primary afferent neurons of the nociceptive pathway therefore reducing synaptic transmission with potent antinociceptive effects.
价 格:¥电议型 号:TP1559L产 地:中国大陆
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T9192BIIB068ADME,inhibit,FcγR,Autoimmune,Bruton tyrosine kinase,TNFα,BIIB 068,ROS,Inhibitor,reversible,Bt
BIIB068 is an selective, reversible and orally active BTK inhibitor (IC50 = 1 nM, Kd = 0.3 nM). BIIB068 is 400 times more selective for BTK than other kinases.
价 格:¥电议型 号:T9192产 地:中国大陆
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T9124Laninamivir octanoateH2N2,CS8958,H3N2,inhaled,CS 8958,Laninamivir octanoate,neuraminidase,inhibit,An
Laninamivir octanoate is a long acting influenza neuraminidase (NA) inhibitor which shows superior anti-influenza virus activity.
价 格:¥电议型 号:T9124产 地:中国大陆
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T9177BPAM344Ionotropic glutamate receptors,GluK3a,PAM,iGluR,BPAM344,BPAM 344,Inhibitor,BPAM-344,KAR,GluK1
BPAM344 is a potent positive allosteric modulator (PAM) of the KAR subunits GluK1b, GluK2a, and GluK3a.
价 格:¥电议型 号:T9177产 地:中国大陆
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TP2309NEUROTENSIN TFA (39379-15-2 free base)NEUROTENSIN TFA (39379 15 2 free base),NEUROTENSIN TFA (393791
Neurotensin (NT) is an endogenous 13 amino acid neuropeptide with profound opioid-independent analgesic effects. It behaves as a neurotransmitter in the brain, as a hormone in the gut, and also as a neuromodulator. It is implicated in the pathophysiology of several CNS disorders (including schizophrenia, Parkinson´s disease, drug abuse, pain, cancer, inflammation, eating disorders and central control of blood pressure) due to its association with a wide variety of neurotransmitter systems
价 格:¥电议型 号:TP2309产 地:中国大陆
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TP1591LOVA G4 peptide acetate(148274-82-2 free base)OVA G-4 peptide acetate(148274-82-2 free base),OVA G4 p
G4 peptide acetate is a variant of the agonist ovalbumin (OVA) peptide (257-264), SIINFEKL. OVA Peptide is a class I (Kb)-restricted peptide epitope of ovalbumin presented by the class I MHC (major histocompatibility complex) molecule, H-2Kb (class I genes of the mouse MHC).
价 格:¥电议型 号:TP1591L产 地:中国大陆
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T8915GlycylsarcosineInhibitor,Gly-Sar,Glycylsarcosine,inhibit
Glycylsarcosine is a dipeptide obtained by formal condensation of the carboxy group of glycine with the amino group of sarcosine
价 格:¥电议型 号:T8915产 地:中国大陆
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T6841FumagillinFumagillin,NSC 9168,Antibiotic,inhibit,Human immunodeficiency virus,Parasite,Inhibitor,NSC
Fumagillin is a selective and potent irreversible inhibitor of Methionine aminopeptidase 2 (MetAP2), used as an antibiotic to treat microsporidiosis.
价 格:¥电议型 号:T6841产 地:中国大陆
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T6917OleuropeinPPARγ,olive,PPAR,Peroxisome proliferator-activated receptors,inhibit,Apoptosis,leaves,Oleu
Oleuropein is an antioxidant polyphenol isolated from olive leaf.
价 格:¥电议型 号:T6917产 地:中国大陆
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T60147BAY-091BAY091
BAY-091 is a novel potent and highly selective PIP4K2A kinase inhibitor.
价 格:¥电议型 号:T60147产 地:中国大陆
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T9154Sodium taurodeoxycholate hydrateSodium taurodeoxycholate hydrate,Sodium taurodeoxycholate,inhibit,In
Sodium taurodeoxycholate hydrate has been used in a study to assess the effect of submicellar concentrations of bile salts on the lipid bilayer membrane.
价 格:¥电议型 号:T9154产 地:中国大陆
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T27691JNJ-DGAT2-AJNJ DGAT2 A,JNJ-DGAT-2-A
JNJ-DGAT2-A, a specific inhibitor of DGAT2(IC50 = 0.14 μM), can be used in studies about the synthesis of triglycerides.
价 格:¥电议型 号:T27691产 地:中国大陆
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T9100BP 897inhibit,BP-897,BP897,cocaine drug-seeking,BP 897,Dopamine Receptor,Inhibitor,addiction,behavio
2-Naphthalenecarboxamide, N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]- is a potent and selective dopamine D3 receptor agonist, and a weak dopamine D2 receptor antagonist, with Kis of 0.92 nM and 61 nM for D3 and D2 receptors, and shows low affinities at D1 and D4 receptors (Kis, 3 and 0.3 μM, respectively).
价 格:¥电议型 号:T9100产 地:中国大陆
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T9140NAcM-OPT HCl(2089293-61-6 free base)NAcMOPT HCl(2089293616 free base),NAcM OPT HCl(2089293 61 6 free
NAcM-OPT HCL is an orally bioavailable cullin neddylation 1 (DCN1) inhibitor that targets N-Acetyl-UBE2M (E2 conjugating enzyme, UBC12) interaction with DCN1 with IC50 of 79 nM.
价 格:¥电议型 号:T9140产 地:中国大陆
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T6788Bitopertininhibit,Bitopertin,RG 1678,RO-4917838,RG-1678,GlyT,Inhibitor,RO 4917838,Glycine transporte
Bitopertin (RG1678, RO-4917838) is a potent inhibitor of glycine transporter 1 (GlyT1), with Ki of 8.1 nM for human hGlyT1b and IC50 of 22-25 nM in Chinese hamster ovary cells.
价 格:¥电议型 号:T6788产 地:中国大陆
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TP1918LLys-[Des-Arg9]Bradykinin,TFALys-[Des-Arg-9]Bradykinin,TFA,Lys [Des Arg9]Bradykinin,TFA,Lys[DesArg9]B
Lys-[Des-Arg9]Bradykinin,TFA is Endogenous potent and highly selective bradykinin B1 receptor agonist (Ki values are 0.12 and > 30000 nM at human B1 and B2 receptors respectively). Hypotensive agent that reduces peripheral vascular resistance in vivo. 16-fold more potent than [Des-Arg9]-Bradykinin.
价 格:¥电议型 号:TP1918L产 地:中国大陆
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T9164BMS-986242glucuronidation,potent,Indoleamine 2,3-Dioxygenase (IDO),cancer,Inhibitor,BMS 986242,inhib
BMS-986242 is an orally active, potent and selective inhibitor of indoleamine-2,3-dioxygenase 1 (IDO1), and it can be used for the research of cancer.
价 格:¥电议型 号:T9164产 地:中国大陆
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T9146ms48107Inhibitor,GPR68,GPCR,MS 48107,ms48107,brain-penetrant,BBB,inhibit,5-HT2B,MS-48107,bioavailabl
MS48107 is a potent and selective positive allosteric modulator of G protein-coupled receptor 68 (GPR68). It is selective for GPR68 over the closely related proton GPCRs, neurotransmitter transporters, and hERG ion channels. It can readily cross the blood-brain barrier (BBB) in mice.
价 格:¥电议型 号:T9146产 地:中国大陆
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TN1911MareinGLUT1,HDAC,Inhibitor,Akt,inhibit,antioxidative,Marein,Histone deacetylases,antihypertensive,AM
Marein shows neuroprotective effect on PC12 cell damage induced by methylglyoxal, which is due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway, it may be a potent compound for preventing/counteracting diabetic encephalopathy.
价 格:¥电议型 号:TN1911产 地:中国大陆
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T6914Oclacitinib maleateOclacitinib,PF03394197,Oclacitinib maleate,inhibit,PF 03394197,Inhibitor,Janus ki
Oclacitinib is a novel inhibitor of JAK family members with IC50 ranging from 10 to 99 nM and JAK1-dependent cytokines with IC50 ranging from 36 to 249 nM, which did not inhibit a panel of 38 non-JAK kinases.
价 格:¥电议型 号:T6914产 地:中国大陆