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T9645CU-115
CU-115 is a selective and potent TLR8 antagonist with IC50 of 1.04 ?M and =>50 ?M for TLR8 and TLR7, respectively. CU-115 decreases production of TNF-α and IL-1β activated by R-848 in THP-1 cells.
价 格:¥电议型 号:T9645产 地:中国大陆
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T8796CAN508inhibit,CAN 508,ATP-competitive,Cyclin dependent kinase,esophageal,cells,CDK,CAN508,Inhibitor,
CAN508 is a potent, ATP-competitive CDK9/cyclin T1 inhibitor with an IC50 of 0.35 μM. It is also a competitive inhibitor of Cdk2-cyclin E with respect to ATP, with Ki and IC50 values of 13.3 and 20 μM, respectively.CAN508 exhibits a 38-fold selectivity for CDK9/cyclin T over other CDK/cyclin complexes. Antitumor activity.
价 格:¥电议型 号:T8796产 地:中国大陆
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T7815LAOD9604 acetate(221231-10-3 free base)AOD9604 acetate(221231103 free base),AOD-9604 acetate(221231-1
AOD9604 acetate is a potential anti-obesity peptide based on the human growth hormone.
价 格:¥电议型 号:T7815L产 地:中国大陆
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T7596FirocoxibLPS,COX-2,fever,ML1785713,Cyclooxygenase,COX,inhibit,Firocoxib,Inhibitor,anti-inflammatory,
Firocoxib is a selective non-steroidal inhibitor of cycooxygenase-2 (COX-2) (IC50 of 0.13 μM), with anti-inflammatory for use in dogs and horses.
价 格:¥电议型 号:T7596产 地:中国大陆
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T26969CCT365623CCT365623
CCT365623 is an orally bioavailable Lysyl Oxidase inhibitor with good anti-LOX potency, selectivity, pharmacokinetic properties, as well as anti-metastatic efficacy.
价 格:¥电议型 号:T26969产 地:中国大陆
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T9617RdRP-IN-2RdRP IN 2,RdRPIN2
RdRP-IN-2 is a RNA dependent RNA polymerase (RdRp) inhibitor. It significantly inhibits SARS-CoV-2 RdRp with an IC50 of 41.2 ?M.It also inhibits Feline coronavirus (FIPV) replication.
价 格:¥电议型 号:T9617产 地:中国大陆
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TN6964TricosaneTricosane
Tricosane is a natural product from Vernonia amygdalina.
价 格:¥电议型 号:TN6964产 地:中国大陆
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T6965RG7112E1 activating enzyme,Inhibitor,RO-5045337,E1/E2/E3 Enzyme,RG7112,Ubiquitin conjugating enzyme,
RG7112 (RO5045337) is an orally bioavailable and selective p53-MDM2 inhibitor.
价 格:¥电议型 号:T6965产 地:中国大陆
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T9609GRK5-IN-2metabolic,bicyclic,insulin,kinase,inhibit,Inhibitor,disease,pyridine-based,GRK5 IN 2,GRK-5-
GRK5-IN-2, a pyridine-based bicyclic compound, is a potent G-protein-coupled receptor kinase 5 (GRK5) inhibitor. It regulates the expression and/or release of insulin and is useful for the metabolic disease research.
价 格:¥电议型 号:T9609产 地:中国大陆
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T9986(E/Z)-ZINC09659342(E/Z)-ZINC09659342,Inhibitor,Lbc-RhoA interaction,Ras,(E/Z)ZINC09659342,Ras superf
(E/Z)-ZINC09659342 is an inhibitor of Lbc-Rho A interaction.
价 格:¥电议型 号:T9986产 地:中国大陆
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T39965NF-κΒ activator 1NFκΒ activator 1,NF κΒ activator 1
NF-κΒ activator 1 is a potent NF-κΒ activator with an EC 50 of 0.9 μM. NF-κΒ activator 1 induces superoxide dismutase (SOD)2 mRNA expression.
价 格:¥电议型 号:T39965产 地:中国大陆
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T8596Ceefourin 1P-glycoprotein,chemosensitizers,inhibit,efflux,protein,resistance,Ceefourin 1,Ceefourin1,
Ceefourin 1 is a highly selective multidrug resistance protein 4 (MRP4) inhibitor.
价 格:¥电议型 号:T8596产 地:中国大陆
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T8963CYM2503Neuropeptide Y Receptor,electrographic seizure,NPY receptor,CYM 2503,seizure,inhibit,CYM2503,
CYM2503 is a positive allosteric modulator (PAM) of the GAL2 receptor that potentiates galanin-induced IP1 production in vitro. It has no affinity for the orthosteric galanin binding site of the receptor (as measured by its inability to displace iodinated galanin, or to induce IP1 accumulation on its own).
价 格:¥电议型 号:T8963产 地:中国大陆
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T61969AChE/BChE-IN-10
AChE/BChE-IN-10 is a potent dual inhibitor of AChE and BChE with IC50 values of 0.176, and 0.47 μM, respectively. AChE/BChE-IN-10 exhibits good blood brain barrier permeability. AChE/BChE-IN-10 can inhibit Aβ-aggregation.
价 格:¥电议型 号:T61969产 地:中国大陆
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T22963McN-A 343McN A 343,McNA 343
McN-A 343 is a selective M1 muscarinic agonist that stimulates muscarinic transmission in sympathetic ganglia. McN-A-343 reduces inflammation and oxidative stress in an experimental model of ulcerative colitis.
价 格:¥电议型 号:T22963产 地:中国大陆
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TN1968N-?Feruloyloctopaminecarcinoma,N-?Feruloyloctopamine,inhibit,Protein kinase B,MAPK,PKB,Inhibitor,Hep
N-Feruloyloctopamine is a natural product.
价 格:¥电议型 号:TN1968产 地:中国大陆
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T9683VX-150Na+ channels,VX-150,indications,Inhibitor,Na channels,orally,inhibit,pain,VX 150,VX150,Sodium
VX-150 is a highly selective NaV1.8 inhibitor relative to the other sodium channel subtypes (>400-fold).
价 格:¥电议型 号:T9683产 地:中国大陆
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T6571Lomerizine dihydrochlorideCa2+ channels,Ca channels,inhibit,Lomerizine,KB 2796,KB2796,Lomerizine dih
Lomerizine dihydrochloride is an antagonist of L- and T-type voltage-gated calcium channels used to treat migraine.
价 格:¥电议型 号:T6571产 地:中国大陆
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T8507MAC-545496Bacterial,S. aureus,Antivirulence,Inhibitor,MAC545496,mprF,nanomolar,GraR,MAC-545496,MRSA,
MAC-545496 is a glycopeptide-resistance-associated protein R (GraR) inhibitor, is an antivirulence agent.
价 格:¥电议型 号:T8507产 地:中国大陆
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TN6963HentriacontaneHentriacontane
Hentriacontane is a natural product with various pharmacological effects including anti-inflammatory, antitumor, and antimicrobial activities.
价 格:¥电议型 号:TN6963产 地:中国大陆