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TP1881L1Pep 2-8 ammonium salt(1541011-97-5 free base)Pep 2 8 ammonium salt(1541011 97 5 free base),Pep 28 am
Pep 2-8 ammonium salt is Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. Potent inhibitor of PCSK9 binding to LDL receptor (IC50 = 0.8 μM). Restores LDL uptake in HepG2 cells treated with PCSK9.
价 格:¥电议型 号:TP1881L1产 地:中国大陆
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T23128PD180970PD-180970,PD180970
PD180970 is an inhibitor of Bcr-Abl with IC50s of 5 nM, 0.8 nM and 50 nM for the autophosphorylation of p210Bcr-Abl, Src and Kit. PD180970 can be used in studies about chronic myelogenous leukemia.
价 格:¥电议型 号:T23128产 地:中国大陆
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T9743FEN1-IN-SC13FEN1 IN SC13,Inhibitor,FEN1INSC13,FEN-1-IN-SC13,inhibit
FEN1-IN-SC13 is a potent inhibitor of DNA fragmentation endonuclease 1 (FEN1)
价 格:¥电议型 号:T9743产 地:中国大陆
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T7083GLPG1837GLPG-1837,ABBV 974,Cystic fibrosis transmembrane conductance regulator,Inhibitor,CFTR,Autoph
GLPG1837 is an effective CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively.
价 格:¥电议型 号:T7083产 地:中国大陆
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T7974Lynestrenolinhibit,progesteronelike,Pregnane,Inhibitor,immunostimulatory,zfPXR,Lynestrenol,PXR,hPXR
Lynestrenol is a synthetic progestational hormone, is the progesterone receptor agonist
价 格:¥电议型 号:T7974产 地:中国大陆
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T9707DB2313
DB2313 is a potent transcription factor PU.1 inhibitor, IC50=14 nM. DB2313 disrupts the interaction of PU.1 with target gene promoters. DB2313 induces apoptosis of acute myeloid leukemia (AML) cells, and has anticancer effects
价 格:¥电议型 号:T9707产 地:中国大陆
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T97193-Hydroxyoctanoic Acid3Hydroxyoctanoic Acid,3 Hydroxyoctanoic Acid
3-Hydroxyoctanoic Acid is one of the hydroxy-carboxylic acids (HCAs) that serve as intermediates of energy metabolism. It is an agonist of the orphan receptor GPR109B.
价 格:¥电议型 号:T9719产 地:中国大陆
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T9713δ-secretase inhibitor 11δ-Secretase inhibitor 11,CNS diseases,Alzheimer’s disease,δ secretase inhibi
δ-secretase inhibitor 11 is an inhibitor of δ-secretase and can be used as a lead compound for translational development of AD treatment.
价 格:¥电议型 号:T9713产 地:中国大陆
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T90597Compound 1549Compound 1549
SSR504734 is an orally active, selective and reversible inhibitor of human, rat, and mouse GlyT1 ( IC 50 =18, 15, and 38 nM, respectively). SSR504734 exhibits activity in schizophrenia, anxiety and depression models [1].
价 格:¥电议型 号:T90597产 地:中国大陆
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T9782Cytochrome CCytochrome C
Cytochrome C, a protein that belongs to class 1 of the c-type cytochrome family, exerts different functions depending on its cellular localization and the conditions in which it operates.
价 格:¥电议型 号:T9782产 地:中国大陆
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T9975GPR183GPR183 antagonist-1,SAE-14,inhibit,SAE 14,SAE14,HL-60,GPR183,Inhibitor,GPR183 antagonist SAE-1
GPR183 is a chemotactic receptor known for its role in the maturation of B cells, and the endogenous ligand is the oxysterol 7α,25-dihydroxycholesterol (7α,25-OHC). GPR183 can be used in research on inflammatory bowel disease (IBD).
价 格:¥电议型 号:T9975产 地:中国大陆
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T9581ARRY-797ARRY 797,ARRY797
ARRY-797 is a potent and selective p38α inhibitor and inhibits LPS-Induced IL-6.
价 格:¥电议型 号:T9581产 地:中国大陆
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T6975Sarcosineinhibit,dysfunction,schizophrenia,Endogenous Metabolite,Sarcosine,Inhibitor,cognitive,depre
Sarcosine is a competitive inhibitor of the type I glycine transporter (GlyT1) and an N-methyl-D-aspartate receptor (NMDAR) co-agonist.
价 格:¥电议型 号:T6975产 地:中国大陆
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T79823,6-Dihydroxyflavoneinhibit,Inhibitor,caspase cascade,cell viability,oxidative stress,3,6-DHF,Apopto
3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway.
价 格:¥电议型 号:T7982产 地:中国大陆
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T9753LEI110HepG2 cells,inhibit,thiol hydrolases,LEI110,Inhibitor,LEI-110,lipolysis,Phospholipase,LEI 110
LEI110 is a potent Phospholipase A2, group XVI (PLA2G16) inhibitor with an Ki value of 20 nM. LEI110 is a selective pan-inhibitor of the HRASLS family of thiol hydrolases (i.e., PLA2G16, HRASLS2, RARRES3 and iNAT).
价 格:¥电议型 号:T9753产 地:中国大陆
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T9789Cevidoplenib dimesylate hydrochlorideCevidoplenib dimesylate hydrochloride
Cevidoplenib dimesylate hydrochloride is a spleen tyrosine kinase (Syk) inhibitor showing potential immunomodulating and anti-inflammatory properties.
价 格:¥电议型 号:T9789产 地:中国大陆
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T61972Pomaglumetad methionil hydrochloride
Pomaglumetad methionine hydrochloride (LY2140023 hydrochloride) is a methionine prodrug of LY404039 with oral activity. LY404039 is a selective mGlu2/3 receptor agonist. Pomaglumetad methionil hydrochloride has research value in schizophrenia.
价 格:¥电议型 号:T61972产 地:中国大陆
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T9759MAO-B-IN-5MAO B IN 5,MAOBIN5
MAO-B-IN-5 is a potent, selective and orally active MAO-B inhibitor with an IC 50 of 0.204 μM. MAO-B-IN-5 has the research potential in Parkinson´s disease (PD) [1].
价 格:¥电议型 号:T9759产 地:中国大陆
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T9100BP 897inhibit,BP-897,BP897,cocaine drug-seeking,BP 897,Dopamine Receptor,Inhibitor,addiction,behavio
2-Naphthalenecarboxamide, N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]- is a potent and selective dopamine D3 receptor agonist, and a weak dopamine D2 receptor antagonist, with Kis of 0.92 nM and 61 nM for D3 and D2 receptors, and shows low affinities at D1 and D4 receptors (Kis, 3 and 0.3 μM, respectively).
价 格:¥电议型 号:T9100产 地:中国大陆