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  • T80269AC3-I, myristoylated;化合物 AC3-I, myristoylatedAutocamtide-3 Derived Inhibitory Peptide;Autocamtide-3

    Myristoylated AC3-I is a biologically active peptide and a myristoylated variant of the Autocamtide-3-Derived Inhibitory Peptide (AC3-I). It acts as a highly specific inhibitor of Calmodulin-Dependent Protein Kinase II (CaMKII) with enhanced resistance to proteolysis. This compound is a derivative of Autocamtide-3, where the Thr-9 phosphorylation site is replaced by Ala.

    价 格:¥电议型 号:T80269产 地:中国大陆

  • T79714HDAC3-IN-2;化合物 HDAC3-IN-2HDAC3-IN-2

    HDAC3-IN-2 (compound 4i), a pyrazinyl hydrazide-based HDAC3 inhibitor with an IC50 of 14 nM, effectively targets triple-negative breast cancer cells. Demonstrating cytotoxic activity, HDAC3-IN-2 exhibits an IC50 of 0.55 μM against 4T1 cells and 0.74 μM against MDA-MB-231 cells. In vivo, it shows anti-tumor efficacy in tumor-bearing mouse models by selectively elevating acetylation of histones H3K9, H3K27, and H4K12, enhancing apoptosis-inducing proteins caspase-3, caspase-7, and cytochrome c, an

    价 格:¥电议型 号:T79714产 地:中国大陆

  • T24132HDAC3-IN-T326;化合物 T24132HDAC3 inhibitor-T326|||T326|||HDAC3 IN T326|||HDAC3 inhibitor T326|||HDAC3IN

    HDAC3-IN-T326 is a potent and selective HDAC3 inhibitor that acts by increasing NF-κB acetylation and activating HIV gene expression in latent HIV-infected cells.

    价 格:¥电议型 号:T24132产 地:中国大陆

  • T24131HDAC3-IN-T247;HDAC3抑制剂T247HDAC3 inhibitor T247|||HDAC3 inhibitor-T247|||HDAC3 IN T247|||T247;HDAC3 i

    HDAC3-IN-T247 (HDAC3 inhibitor T247) is a selective and potent histone deacetylase 3 (HDAC3) inhibitor with anticancer and antiviral activities.HDAC3-IN-T247 induces NF-κB acetylation in human colon cancer HCT116 cells in a dose-dependent manner.HDAC3-IN-T247 inhibits cancer cell proliferation. HDAC3-IN-T247 inhibits cancer cell proliferation.

    价 格:¥电议型 号:T24131产 地:中国大陆

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