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TP1559LZiconotide Acetate (107452-89-1 free base)analgesic,non-opioid,Ziconotide Acetate (107452891 free
Ziconotide is an analgesic agent and has been used to treat neuropathic and non-neuropathic pain. Ziconotide acts by binding to N-type calcium channels situated on the terminal part of primary afferent neurons of the nociceptive pathway therefore reducing synaptic transmission with potent antinociceptive effects.
价 格:¥电议型 号:TP1559L产 地:中国大陆
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TP1881L1Pep 2-8 ammonium salt(1541011-97-5 free base)Pep 2 8 ammonium salt(1541011 97 5 free base),Pep 28 am
Pep 2-8 ammonium salt is Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. Potent inhibitor of PCSK9 binding to LDL receptor (IC50 = 0.8 μM). Restores LDL uptake in HepG2 cells treated with PCSK9.
价 格:¥电议型 号:TP1881L1产 地:中国大陆
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TQ0150LevcromakalimPotassium Channel,KcsA,Inhibitor,inhibit,BRL38227,BRL-38227,Levcromakalim
Levcromakalim is an activator of the ATP-sensitive K+ channel.
价 格:¥电议型 号:TQ0150产 地:中国大陆
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TN12373-O-Methylgallic acidAnthocyanin,3 O Methylgallic acid,inhibit,3OMethylgallic acid,metabolite,anti-c
3,4-Dihydroxy-5-methoxybenzoic acid reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins and may offer protection against colon cancer after its formation in the gut. 3,4-Dihydroxy-5-methoxybenzoic acid inhibits transcription factors NF-κB, AP-1, STAT-1, and OCT-1 which are known to be activated in colorectal cancer.
价 格:¥电议型 号:TN1237产 地:中国大陆
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TP1789LMalantide acetate(86555-35-3 free base)Malantide acetate(86555 35 3 free base),Malantide acetate(865
Malantide acetate is a dodecapeptide phosphorylated by cyclic AMP-dependent protein kinase (PKA), and increases PKA activity.Malantide is a synthetic peptide that is phosphorylated by PKA and is used to measure PKA activity in vitro.
价 格:¥电议型 号:TP1789L产 地:中国大陆
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TN1438beta-Amyrin acetateHMG-CoA,betaAmyrin acetate,LDL,Fungal,inhibit,Inhibitor,arthritic,hemolysis,antif
beta-Amyrin acetate inhibits HMG-CoA Reductase (HMGCR) and sEH activity with IC50 of 3.4 μM. beta-Amyrin acetate has anti-inflammatory, antifungal, antioxidant, and anti-hyperlipidemic activities.
价 格:¥电议型 号:TN1438产 地:中国大陆
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T7312AX20017AX 20017,AX20017,Inhibitor,Bacterial,inhibit,AX-20017
AX20017 is a small-molecule protein kinase G (PknG) inhibitor(IC50 : 0.39 μM). It acts by blocking the proliferation of M. tuberculosis.
价 格:¥电议型 号:T7312产 地:中国大陆
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T8796CAN508inhibit,CAN 508,ATP-competitive,Cyclin dependent kinase,esophageal,cells,CDK,CAN508,Inhibitor,
CAN508 is a potent, ATP-competitive CDK9/cyclin T1 inhibitor with an IC50 of 0.35 μM. It is also a competitive inhibitor of Cdk2-cyclin E with respect to ATP, with Ki and IC50 values of 13.3 and 20 μM, respectively.CAN508 exhibits a 38-fold selectivity for CDK9/cyclin T over other CDK/cyclin complexes. Antitumor activity.
价 格:¥电议型 号:T8796产 地:中国大陆
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T6908NSC 228155Epidermal growth factor receptor,Histone Acetyltransferase,EGFR,HER1,HATs,inhibit,Inhibito
NSC228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.
价 格:¥电议型 号:T6908产 地:中国大陆
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T8084Dimethyl 4-hydroxyisophthalateDimethyl 4-hydroxyisophthalate,inhibit,Dimethyl 4 hydroxyisophthalate,
Dimetghyl 4-Hydroxyisophthalate is a methyl salicylate analogue, used as a building block in the chemical synthesis.
价 格:¥电议型 号:T8084产 地:中国大陆
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TP1545L1FFAGLDD amine saltFFAGLDD amine salt
FFAGLDD amine salt is MMP9 selective cleavage peptides, which used for cytosolic delivery of Doxorubi-cin (DOX) and achieve temporally and spatially controlled slow drug delivery and release.
价 格:¥电议型 号:TP1545L1产 地:中国大陆
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TN6982Diethyl phthalate
Diethyl phthalate is a endocrine disrupter affecting the apoptotic system in PC12 cells. Diethyl phthalate is widely used in many plastics and personal care products.
价 格:¥电议型 号:TN6982产 地:中国大陆
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T6507Gabapentin hydrochlorideInhibitor,Gabapentin hydrochloride,Gabapentin,Calcium Channel,Ca channels,in
Gabapentin HCl is a GABA analogue, used to treat seizures and neuropathic pain.
价 格:¥电议型 号:T6507产 地:中国大陆
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T38163ML-148ML-148,ML 148,selective,Inhibitor,prostaglandin-signaling,15-PGDH,15-Hydroxyprostaglandin dehy
ML-148 is a selective inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH, IC50 = 56 nM). ML-148 can be used to profile across a panel of related dehydrogenase or reductase enzymes and in studies about prostaglandin-signaling pathways.
价 格:¥电议型 号:T38163产 地:中国大陆
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T6874Lercanidipine hydrochlorideantihypertensive,Inhibitor,calcium,Lercanidipine,Lercanidipine hydrochlor
Lercanidipine is a calcium channel blocker of the dihydropyridine class.
价 格:¥电议型 号:T6874产 地:中国大陆
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T6683STF-62247renal,STF-62247,VHL,carcinoma,inhibit,cytotoxic,cell,RCC,Inhibitor,STF62247,intracytoplasmi
STF-62247 is TGN inhibitor with IC50 of 0.625 μM and 16 μM in RCC4 and RCC4/VHL cells, respectively.
价 格:¥电议型 号:T6683产 地:中国大陆
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TN6770Malabaricone AMalabaricone A
Malabaricone A is a bioactive chemical.
价 格:¥电议型 号:TN6770产 地:中国大陆
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TN1019Beta-mangostinBeta mangostin,Bacterial,pathway,Apoptosis,carcinoma,migration,antibacterial,inhibit,c
Beta-Mangostin (β-Mangostin) is a xanthone compound with antibacterial and antimalarial activities. Beta-Mangostin (β-Mangostin) present in Cratoxylum arborescens and exhibits antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 6.25 μg/mL. Beta-Mangostin possesses in vitro antimalarial activity against Plasmodium falciparum, with an IC50 of 3.00 μg/mL. beta-Mangostin has potent anticancer activity against various cancers (such as hepatocellular carcinoma, leukaemic).
价 格:¥电议型 号:TN1019产 地:中国大陆
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T38344Lalistat 1
Lalistat 1 is an inhibitor of lysosomal acid lipase (LAL, IC50 = 68 nM) and IgA1 protease for H. influenzae. Lalistat 1 can be used in studies about niemann-pick type C diseases.
价 格:¥电议型 号:T38344产 地:中国大陆
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T9820GPI-1485neurofunctional,regeneration,Inhibitor,ligand,stroke,GPI-1485,GPI 1485,inhibit,immunophilin,
GPI-1485 (GM1485) is a nonimmunosuppressive immunophilin ligand, promoting neurofunctional improvement and neural regeneration following stroke.
价 格:¥电议型 号:T9820产 地:中国大陆