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T71736AMG-628, (R)-;化合物 AMG-628, (R)-AMG-628, (R)-
AMG-628, (R)- is the R isomer of AMG-628 --- a potent, ATP-competitive inhibitor of Raf kinases. AMG-628 displays selectivity for Raf kinases and inhibits activation of tyrosine protein kinases such as VEGFR2, Lyn, Flt1 and Fms. AMG-628 has shown to inhibit growth, and induces cell cycle arrest and apoptosis in colon and melanoma cell lines with the B-RafV600E mutation.
价 格:¥电议型 号:T71736产 地:中国大陆
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T68523AMG-628, (S)-;化合物 AMG-628, (S)-AMG-628, (S)-
AMG-628, (S)-, is the S isomer of AMG-628 --- a potent, ATP-competitive inhibitor of Raf kinases. AMG-628 displays selectivity for Raf kinases and inhibits activation of tyrosine protein kinases such as VEGFR2, Lyn, Flt1 and Fms. AMG-628 has shown to inhibit growth, and induces cell cycle arrest and apoptosis in colon and melanoma cell lines with the B-RafV600E mutation.
价 格:¥电议型 号:T68523产 地:中国大陆
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T29973AMG-628;化合物 T29973AMG628|||AMG 628|||CHEMBL226574|||UNII-28J966TN3X;AMG628|||AMG 628|||CHEMBL226574|
AMG-628 is an effective and ATP-competitive RAF kinase inhibitor. AMG-628 has been shown to inhibit growth and induce cell cycle arrest and apoptosis in colon and melanoma cell lines with B-RAFV600E mutations.
价 格:¥电议型 号:T29973产 地:中国大陆