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T6760APS-2-79 hydrochlorideMAP2K,MAPKK,Inhibitor,Mitogen-activated protein kinase kinase,APS 2 79 hydroch
APS-2-79 is a MAPK antagonist that modulating KSR-dependent MAPK signalling by antagonizing RAF heterodimerization as well as the conformational changes required for phosphorylation and activation of KSR-bound MEK.
价 格:¥电议型 号:T6760产 地:中国大陆
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T70004APS-2-79;化合物 APS-2-79APS-2-79
APS-2-79, a KSR-dependent MEK antagonist, disrupts ATP (biotin) binding within the KSR2-MEK1 complex, achieving an inhibitory concentration (IC50) of 120 nM. This action stabilizes the KSR inactive state and antagonizes oncogenic Ras-MAPK signaling.
价 格:¥电议型 号:T70004产 地:中国大陆
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T6760APS-2-79 hydrochloride;化合物APS-2-79APS-2-79 HCl|||APS-2-79;APS-2-79 HCl|||APS-2-79
APS-2-79 hydrochloride (APS-2-79 HCl) is a MAPK antagonist that modulating KSR-dependent MAPK signalling by antagonizing RAF heterodimerization as well as the conformational changes required for phosphorylation and activation of KSR-bound MEK.
价 格:¥电议型 号:T6760产 地:中国大陆