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T13253UmibecestatBACE,Beta-secretase,inhibit,CNP-520,β-Secretase,CNP 520,Inhibitor
Umibecestat is an inhibitor of beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1), with IC50s of 11 nM and 10 nM for human BACE-1 and mouse BACE-1, respectively. Umibecestat can be used for the research of alzheimer´s disease.
价 格:¥电议型 号:T13253产 地:中国大陆
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T6249AvagacestatBMS-708163
Avagacestat (BMS-708163) is a potent, selective, orally bioavailable γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM, demonstrating a 193-fold selectivity against Notch. Phase 2.
价 格:¥电议型 号:T6249产 地:中国大陆
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T4532LinrodostatBMS-986205
BMS-986205 is a selective indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitor.
价 格:¥电议型 号:T4532产 地:中国大陆
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T1984CinaciguatBAY 58-2667
Cinaciguat (BAY 58-2667) is the first of a new class of soluble guanylate cyclase (sGC) activators in Clinicalal development for acute decompensated heart failure.
价 格:¥电议型 号:T1984产 地:中国大陆
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T1867OtenaproxesulATB 346
ATB-346 is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity.
价 格:¥电议型 号:T1867产 地:中国大陆
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T17226VericiguatBAY1021189;维利西呱
Vericiguat is a potent and orally available guanylate cyclase stimulator.
价 格:¥电议型 号:T17226产 地:中国大陆
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T13383ZamicastatBIA 5-1058
Zamicastat is an inhibitor of dopamine β-hydroxylase (DBH), and is also a concentration-dependent dual inhibitor of P-gp and BCRP(IC50 values of 73.8 μM and 17.0 μM, respectively).
价 格:¥电议型 号:T13383产 地:中国大陆
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T0424Bismuth subsalicylatBismuth subsalicylat,Bismuth(III) salicylate basic,Bismuth oxysalicylate
Bismuth subsalicylate is the active ingredient in the popular medication Pepto-Bismol that is used to treat nausea, heartburn, indigestion, upset stomach, diarrhea, and other temporary discomforts of the stomach and gastrointestinal tract.
价 格:¥电议型 号:T0424产 地:美洲
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T10394ATB107ATB107
ATB107 is a potent and novel inhibitor of indole-3-glycerol phosphate synthase (IGPS, KD: 3 μM).
价 格:¥电议型 号:T10394产 地:美洲
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T14525BegacestatBegacestat,GSI-953,
Begacestat (GSI-953) is an amyloid precursor protein gamma-secretase (IC50Aβ40=15 nM) inhibitor. Which is used for treatment of Alzheimer´s disease.
价 格:¥电议型 号:T14525产 地:美洲
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T1852BelinostatBelinostat,NSC726630,PX-105684
Belinostat is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing apoptosis, promoting cellular differentiation, and inhibit
价 格:¥电议型 号:T1852产 地:美洲
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T1867ATB 346ATB 346
ATB-346 is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity.
价 格:¥电议型 号:T1867产 地:美洲
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T19574TBHBATBHBA,2,4,6-Tribromo-3-hydroxybenzoic acid,
TBHBA (2,4,6-Tribromo-3-hydroxybenzoic acid) is a chemical compound.
价 格:¥电议型 号:T19574产 地:美洲
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T5782BevirimatBevirimat,PA-457,MPC-4326
Bevirimat(PA-457) is a first-in-class inhibitor of HIV-1 maturation, blocking the cleavage of the Gag capsid (CA) precursor, CA-SPI, to mature CA protein during virion maturation.
价 格:¥电议型 号:T5782产 地:美洲
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T6011BatimastatBatimastat,BB94,
Batimastat (BB-94) is an effective, broad-spectrum matrix metalloprotease (MMP) inhibitor. Batimastat induces extracellular matrix degradation and inhibits angiogenesis, tumor growth and invasion, and metastasis.
价 格:¥电议型 号:T6011产 地:美洲
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T83128Aminooxy CatB-LXR;化合物 Aminooxy CatB-LXRAminooxy CatB-LXR
Compound 10, Aminooxy CatB-LXR, constitutes an agent-linker conjugate for antibody-drug conjugates (ADC) [1].
价 格:¥电议型 号:T83128产 地:中国大陆
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T82953ATBTA-Eu3+;化合物 ATBTA-Eu3+ATBTA-Eu3+
ATBTA-Eu3+ is a fluorescent europium chelate useful for DNA labeling [1].
价 格:¥电议型 号:T82953产 地:中国大陆
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T7201Nelociguat;化合物NelociguatBAY60-4552;N-[4,6-二氨基-2-[1-[(2-氟苯基)甲基]-1H-吡唑并[3,4-B]吡啶-3-基]-5-嘧啶]-氨基甲酸甲酯|||B
Nelociguat (BAY60-4552)(BAY60-4552) is a soluble guanylate cyclase stimulator (sGC stimulator). Soluble guanylate cyclase (sGC) is a key enzyme in the nitric oxide (NO) signalling pathway.
价 格:¥电议型 号:T7201产 地:中国大陆
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T71656ATB-346, (S)-;化合物 ATB-346, (S)-ATB-346, (S)-
ATB-346, (S)-, is the S form of ATB-346. ATB-346 is a novel hydrogen sulfide-releasing anti-inflammatory drug which induces apoptosis of human melanoma cells and inhibits melanoma development in vivo.
价 格:¥电议型 号:T71656产 地:中国大陆
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T70748Bisthianostat;化合物 BisthianostatBisthianostat
Bisthianostat, also known as CF367 or CF367;-C, is a novel Orally Efficacious Pan-HDAC Inhibitor. Bisthianostat selectively binds to and inhibits HDACs, which inhibits deacetylation of histone proteins and leads to the accumulation of highly acetylated histones. This may result in an induction of chromatin remodeling, the inhibition of tumor oncogene transcription, and the selective transcription of tumor suppressor genes. This prevents cell division, induces cell cycle arrest and apoptosis. Thi
价 格:¥电议型 号:T70748产 地:中国大陆