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T38011C2 Adamantanyl Globotriaosylceramide (d18:1/2:0);C2 Adamantanyl Globotriaosylceramide (d18:1/2:0)C2
C2 Adamantanyl globotriaosylceramide (AdaGb3) is a bioactive sphingolipid and water-soluble form of globotriaosylceramide that contains an adamantanyl group in place of the fatty acyl chain. It inhibits Vero toxin binding to globotriaosylceramide in an ELISA assay when used at a concentration of 10 μM. AdaGb3 decreases cell surface expression of P-glycoprotein (P-gp) and reduces efflux of rhodamine 123 in MDCK cells. It also increases apical-to-basal transport of vinblastine in human intestinal
价 格:¥电议型 号:T38011产 地:中国大陆
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T37440C2 Adamantanyl Galactosylceramide (d18:1/2:0);C2 Adamantanyl Galactosylceramide (d18:1/2:0)C2 Adaman
C2 Adamantanyl Galactosylceramide (d18:1/2:0) (AdaGalCer) is a bioactive sphingolipid. It reduces globotriaosylceramide 3 synthesis from exogenous lactosylceramide in microsomes. AdaGalCer stimulates recombinant glucocerebrosidase activity in a pH-dependent manner. It activates glucocerebrosidase to decrease glucosylceramide accumulation in fibroblasts and lymphoblasts isolated from patients with Gaucher and Fabry disease, respectively.
价 格:¥电议型 号:T37440产 地:中国大陆