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T19182Afegostat D-TartrateAfegostat D-Tartrate,D-Isofagomine D-Tartrate,Isofagomine D-Tartrate
Afegostat D-Tartrate is a pharmacological chaperone that specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum with high affinity.
价 格:¥电议型 号:T19182产 地:美洲
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T72998L-Afegostat;化合物 L-Afegostat5-epi-Isofagomine;5-epi-Isofagomine
L-Afegostat (5-epi-Isofagomine), a glycosidase inhibitor and an iminosugar, is utilized in carbohydrate synthesis. It demonstrates β-Glucosidase inhibition with a Ki of 30 μM.
价 格:¥电议型 号:T72998产 地:中国大陆
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T71476Afegostat TFA;化合物 Afegostat TFAAfegostat TFA
Afegostat, aslo known as Isofagomine, and AT2101, was an experimental drug for the treatment of certain forms of Gaucher´s disease. Isofagomine (IFG) is an acid β-glucosidase (GCase) active site inhibitor that acts as a pharmacological chaperone. FG inhibits GCase with K(i) ~30 nM for wild-type and mutant enzymes (N370S and V394L). Administration of IFG (30 mg/kg/day) to the mice homozygous for GCase mutations (V394L, D409H, or D409V) led to increased GCase activity in visceral tissues and
价 格:¥电议型 号:T71476产 地:中国大陆
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T23653Afegostat HCl;化合物 T23653Afegostat|||AT-2101|||Afegostat hydrochloride|||AT2101;Afegostat|||AT-2101||
Afegostat is an acid β-glucosidase (GCase) active site inhibitor that acts as a pharmacological chaperone. Afegostat inhibits GCase with K(i) ~30 nM for wild-type and mutant enzymes. Afegostat was an experimental drug for the treatment of certain forms of Gaucher´s disease.
价 格:¥电议型 号:T23653产 地:中国大陆
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T19182Afegostat D-Tartrate;化合物 T19182Isofagomine D-Tartrate|||D-Isofagomine D-Tartrate;Isofagomine D-Tartr
Afegostat D-Tartrate is a pharmacological chaperone that specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum with high affinity.
价 格:¥电议型 号:T19182产 地:中国大陆
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T19181Afegostat;化合物 T19181D-Isofagomine|||Isofagomine;D-Isofagomine|||Isofagomine
Afegostat is a pharmacological chaperone that specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum with high affinity.
价 格:¥电议型 号:T19181产 地:中国大陆