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T14152Akt1 and Akt2-IN-1Akt1 and Akt2-IN-1
Akt1 and Akt2-IN-1 is an allosteric inhibitor of Akt1 (IC50=3.5 nM) and Akt2 (IC50=42 nM). It has potent and balanced activity.
价 格：￥电议型 号：T14152产 地：美洲
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T79214Tubulin/AKT1-IN-1；化合物 Tubulin/AKT1-IN-1Tubulin/AKT1-IN-1
Tubulin/AKT1-IN-1 (Compound D1-1) serves as an inhibitor of both tubulin polymerization and AKT pathway activation, effectively suppressing proliferation and metastasis of H1975 cells while modestly inducing apoptosis. This compound is utilized in the study of non-small-cell lung cancer (NSCLC) [1].
价 格：￥电议型 号：T79214产 地：中国大陆
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T73255Akt1-IN-1；化合物 Akt1-IN-1Akt1-IN-1
Akt1-IN-1 is a potent and selective inhibitor of Akt1, demonstrating an IC50 of 18.79 nM in MIA PaCa-2 cells, indicating its high efficacy in inhibiting this specific kinase. Notably, it shows no significant teratogenicity, hepatotoxicity, or cardiotoxicity (No Observed Adverse Effect Level > 100 ?M), making it a viable candidate for anticancer research.
价 格：￥电议型 号：T73255产 地：中国大陆
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T72886Akt1&PKA-IN-2；化合物 Akt1&PKA-IN-2Akt1&PKA-IN-2
Akt1&PKA-IN-2 ((R)-29), a compound with specificity towards PKB/AKT and notable selectivity for cyclin-dependent kinase 2 (CDK2), effectively inhibits AKT1, PKAa, and CDK2a with IC50 values of 0.007 ?M, 0.01 ?M, and 0.69 ?M, respectively.
价 格：￥电议型 号：T72886产 地：中国大陆
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T72885Akt1&PKA-IN-1；化合物 Akt1&PKA-IN-1Akt1&PKA-IN-1
Akt1&PKA-IN-1 is a potent dual inhibitor targeting Akt and PKA, exhibiting IC50 values of 0.11 μM for Akt, 0.03 μM for PKAα, and 9.8 μM for CDK2. Notably, it demonstrates selectivity for cyclin-dependent kinase 2 (CDK2).
价 格：￥电议型 号：T72885产 地：中国大陆
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T14152Akt1 and Akt2-IN-1；化合物 T14152Akt1 and Akt2-IN-1
Akt1 and Akt2-IN-1 is an allosteric inhibitor of Akt1 (IC50=3.5 nM) and Akt2 (IC50=42 nM). It has potent and balanced activity.
价 格：￥电议型 号：T14152产 地：中国大陆
