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T71232Alisertib sodium hydrate；化合物 Alisertib sodium hydrateAlisertib sodium hydrate
Alisertib sodium hydrate is a salt of Alisertib --- an inhibitor of Aurora A kinase with potential antineoplastic activity. Alisertib binds to and inhibits Aurora A kinase, which may result in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregation, and inhibition of cell proliferation.
价 格：￥电议型 号：T71232产 地：中国大陆
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T38428Alisertib sodium；Alisertib sodiumMLN 8237 sodium；MLN 8237 sodium
Alisertib sodium (MLN 8237) is a potent and specific inhibitor (IC50 = 1.2 nM) of Aurora A kinase, an enzyme involved in cell division. By binding to Aurora A kinase, Alisertib sodium disrupts the formation of the mitotic spindle and causes abnormal cell division. At the molecular level, it acts on the AKT/mTOR/AMPK/p38 pathway, leading to the induction of apoptosis and autophagy in leukemic cells. This compound exhibits significant antitumor activity.
价 格：￥电议型 号：T38428产 地：中国大陆
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T2241Alisertib；化合物AlisertibMLN 8237；MLN 8237|||4-[[9-氯-7-(2-氟-6-甲氧基苯基)-5H-嘧啶并[5,4-D][2]苯并氮杂卓-2-基]氨基]-2-甲氧
Alisertib (MLN 8237) is an Aurora A kinase inhibitor (IC50=1.2 nM) with oral activity and selectivity. Alisertib has antitumor activity, induces apoptosis and autophagy, and induces cell cycle arrest.
价 格：￥电议型 号：T2241产 地：中国大陆
