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T2615Flavopiridol hydrochlorideHL 275;Alvocidib Hydrochloride;FLAVOPIRIDOL HCL;NSC 649890 HCl;MDL 107826A
Alvocidib Hydrochloride is a synthetic N-methylpiperidinyl chlorophenyl flavone compound. As an inhibitor of cyclin-dependent kinase, alvocidib induces cell cycle arrest by preventing phosphorylation of cyclin-dependent kinases (CDKs) and by down-regulati
价 格:¥电议型 号:T2615产 地:中国大陆
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T2615Flavopiridol hydrochlorideFlavopiridol hydrochloride,Alvocidib Hydrochloride,FLAVOPIRIDOL HCL
Alvocidib Hydrochloride is a synthetic N-methylpiperidinyl chlorophenyl flavone compound. As an inhibitor of cyclin-dependent kinase, alvocidib induces cell cycle arrest by preventing phosphorylation of cyclin-dependent kinases (CDKs) and by down-regulati
价 格:¥电议型 号:T2615产 地:美洲
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T6837Flavopiridol;夫拉平度L868275|||Alvocidib|||NSC 649890 HCl|||HMR-1275;L868275|||Alvocidib|||夫拉平度|||NSC 64
Flavopiridol (Alvocidib) (Alvocidib) competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM. It is 7.5-fold more selective for CDK1, 2, 4, 6 versus CDK7. Flavopiridol is initially found to inhibit EGFR and PKA. Phase 1/2.
价 格:¥电议型 号:T6837产 地:中国大陆
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T2615Flavopiridol hydrochloride化合物Flavopiridol hydrochlorideAlvocidib Hydrochloride|||NSC 649890|||MDL 10
Flavopiridol hydrochloride (MDL 107826A) is a synthetic N-methylpiperidinyl chlorophenyl flavone compound. As an inhibitor of cyclin-dependent kinase, alvocidib induces cell cycle arrest by preventing phosphorylation of cyclin-dependent kinases (CDKs) and by down-regulating cyclin D1 and D3 expression, resulting in G1 cell cycle arrest and apoptosis. This agent is also a competitive inhibitor of adenosine triphosphate activity.
价 格:¥电议型 号:T2615产 地:中国大陆