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T7877ThiacetazoneAntitubercular,thiourea-containing,monooxygenase,Inhibitor,Amithiozone,EthA,inhibit,Anti
Thioacetazone is a thiosemicarbazone that thioacetazone treatment of pulmonary tuberculosis
价 格:¥电议型 号:T7877产 地:中国大陆
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T79379Antitubercular agent-39;化合物 Antitubercular agent-39Antitubercular agent-39
Antitubercular agent-39 (Compound P1) is a potent agent effective against both drug-resistant strains and drug-susceptible clinical isolates of tuberculosis, exhibiting inhibition of the Mtb strain H37Rv with a minimum inhibitory concentration (MIC) of less than 1 μM [1].
价 格:¥电议型 号:T79379产 地:中国大陆
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T79288Antitubercular agent-38;化合物 Antitubercular agent-38Antitubercular agent-38
Antitubercular Agent-38, a derivative of Benzothiazinones (BTZs), demonstrates potent antituberculosis activity while maintaining low cardiac toxicity and minimal cell cytotoxicity [1]. This orally active compound is a promising therapeutic in the treatment of tuberculosis.
价 格:¥电议型 号:T79288产 地:中国大陆
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T78918Antitubercular agent-37;化合物 Antitubercular agent-37Antitubercular agent-37
Antitubercular Agent-37 exhibits antimycobacterial properties and functions as an antibacterial agent with an MIC (minimum inhibitory concentration) value of 0.16 μg/mL, making it suitable for tuberculosis research [1].
价 格:¥电议型 号:T78918产 地:中国大陆
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T75008Antitubercular agent-36;化合物 Antitubercular agent-36Antitubercular agent-36
Antitubercular agent-36 (compound 53) is an effective inhibitor of Mycobacterium tuberculosis H37Rv, displaying a minimum inhibitory concentration (MIC90) of 1.25 μg/mL and is utilized in tuberculosis research [1].
价 格:¥电议型 号:T75008产 地:中国大陆
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T75007Antitubercular agent-35;化合物 Antitubercular agent-35Antitubercular agent-35
Antitubercular Agent-35 (compound 42l) is an antitubercular agent effective against Mtb H37Rv and M. Marinum, exhibiting MIC 90 values of 1.25 and 2 μg/mL, respectively. It demonstrates resistance to metabolic degradation by human liver microsomes, rendering it a potential candidate for tuberculosis research [1].
价 格:¥电议型 号:T75007产 地:中国大陆
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T75006Antitubercular agent 34;化合物 Antitubercular agent 34Antitubercular agent 34
Antitubercular agent 34 (compound 42g) effectively inhibits Mtb H37Rv growth, exhibiting a MIC 90 value of 1.25 ?g/mL and demonstrates resistance to metabolic degradation by human liver microsomes, proving its potential for tuberculosis research [1].
价 格:¥电议型 号:T75006产 地:中国大陆
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T64045Antitubercular agent-20;化合物 Antitubercular agent-20Antitubercular agent-20
Antitubercular agent-20 is an orally active antitubercular agent. agent-20 showed low cytotoxicity and good tolerability in BALB/c mice.
价 格:¥电议型 号:T64045产 地:中国大陆
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T63945Antitubercular agent-19;化合物 Antitubercular agent-19Antitubercular agent-19
Antitubercular agent-19 is an antitubercular agent. antitubercular agent-19 showed good antitubercular effects against MTB H37Rv and MDR-MTB (MIC <0.016 μg/ml). antitubercular agent-19 showed low cytotoxicity and relatively high acute lethality in BALB/c mice. Antitubercular agent-19 exhibited low cytotoxicity and relatively high acute lethal toxicity in BALB/c mice.
价 格:¥电议型 号:T63945产 地:中国大陆
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T63755Antitubercular agent-22;化合物 Antitubercular agent-22Antitubercular agent-22
Antitubercular agent-22 (Compound 2) is an effective anti-Candida and anti-tuberculosis agent against Candida albicans MTCC 3017 (MIC: 2.34 μg/ml) and M. tuberculosis (H37Rv) (MIC: 2 μg/ml).
价 格:¥电议型 号:T63755产 地:中国大陆
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T63525Antitubercular agent-23;化合物 Antitubercular agent-23Antitubercular agent-23
Antitubercular agent-23 is an effective anti-Candida and anti-tuberculosis agent against Candida albicans MTCC 3017 (MIC: 1.1 μg/ml) and M. tuberculosis (H37Rv) (MIC: 1 μg/ml).
价 格:¥电议型 号:T63525产 地:中国大陆
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T63414Antitubercular agent-31;化合物 Antitubercular agent-31Antitubercular agent-31
Antitubercular agent-31 is an antitubercular agent that inhibits M. tuberculosisH37Rv (MIC: 0.03 μM) and also inhibits DprE1 (IC50: 1.1 μM).
价 格:¥电议型 号:T63414产 地:中国大陆
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T63319Antitubercular agent-32;化合物 Antitubercular agent-32Antitubercular agent-32
Antitubercular agent-32 is a Benzothiazinone derivative that inhibits Mycobacterium tuberculosis and exhibits good metabolic stability and water solubility. Antitubercular agent-32 can act on decaprenylphosphoryl-β-D-ribose 2´-oxidase (DprE1, IC50: 3.9 μM) and exhibits antitubercular effects.
价 格:¥电议型 号:T63319产 地:中国大陆
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T63025Antitubercular agent-26;化合物 Antitubercular agent-26Antitubercular agent-26
Antitubercular agent-26 (Compound 32) is an orally active antitubercular agent that acts on M. tuberculosisH37Rv cells (IC50: 0.50 μM extracellularly and 0.51 μM intracellularly). 26 has good metabolic stability, low risk of cardiotoxicity and no genotoxicity.
价 格:¥电议型 号:T63025产 地:中国大陆
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T62066Antitubercular agent-29;化合物 Antitubercular agent-29Antitubercular agent-29
Antitubercular agent-29 (compound 6xa) is a potent drug resistant (DR) Mycobacterium tuberculosis (Mtb) inhibitor. Antitubercular agent-29 exhibits MIC of 0.03 μg/mL against drug-susceptible (DS)-Mtb strains, MIC of 0.03-0.06 μg/mL against DR-Mtb strains. Antitubercular has favourable selectivity (SI>40) against Vero cells.
价 格:¥电议型 号:T62066产 地:中国大陆
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T61928Antitubercular agent-25;化合物 Antitubercular agent-25Antitubercular agent-25
Antitubercular agent-25 (Compound 28) is an anti-tubercular agent. Antitubercular agent-25 shows an extracellular IC50 of 0.42 μM and an intracellular IC50 of 0.20 μM against M. tuberculosis H37Rv. Antitubercular agent-25 shows good metabolic stability.
价 格:¥电议型 号:T61928产 地:中国大陆
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T61595Antitubercular agent-12;化合物 Antitubercular agent-12Antitubercular agent-12
Antitubercular agent-12 (Compound 2c) is a highly effective antitubercular agent, with a MIC (Minimum Inhibitory Concentration) value of 1.439 μg/mL. Notably, Antitubercular agent-12 exhibits significantly reduced cytotoxicity, reflected by a CC50 (50% Cytotoxic Concentration) value of 57.34 μg/mL [1].
价 格:¥电议型 号:T61595产 地:中国大陆
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T61520Antitubercular agent-24;化合物 Antitubercular agent-24Antitubercular agent-24
Antitubercular agent-24 (Compound 1) exhibits anti-tubercular properties against M. tuberculosis H37Rv. It demonstrates an extracellular IC50 of 0.83 μM and an intracellular IC50 of 0.17 μM [1].
价 格:¥电议型 号:T61520产 地:中国大陆
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T61471Antitubercular agent-13;化合物 Antitubercular agent-13Antitubercular agent-13
Antitubercular agent-13 (Compound 3d) is an antitubercular agent with MIC values of 0.007 μg/mL and 1.851 μg/mL against MTB H37Rv and MDR-MTB 16833, respectively. Antitubercular agent-13 shows metabolic instability [1].
价 格:¥电议型 号:T61471产 地:中国大陆
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T61252Antitubercular agent-16;化合物 Antitubercular agent-16Antitubercular agent-16
Antitubercular agent-16 (Compound 5q) is a potent antitubercular agent exhibiting high efficacy against various strains of M. tuberculosis, including H37Rv, CF16, CF61, CF76, CF152, and CF161, with MIC 90 values ranging from 0.40 to 23.51 μg/mL. Notably, Antitubercular agent-16 demonstrates minimal cytotoxicity towards macrophages and pulmonary fibroblasts, further highlighting its potential as a therapeutic agent [1].
价 格:¥电议型 号:T61252产 地:中国大陆