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T6767TCS7010Aurora Kinase,inhibit,TCS 7010,Apoptosis,TCS-7010,TCS7010,Inhibitor
Aurora A Inhibitor I is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay. It is 1000-fold more selective for Aurora A than Aurora B.
价 格：￥电议型 号：T6767产 地：中国大陆
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T9040Aurora kinase inhibitor-2inhibit,Aurora-A,Aurora kinase inhibitor2,Aurora Kinase,ATP-competitive,Aur
Aurora Kinase Inhibitor II is a cell-permeable anilinoquinazoline that inhibit the activity of Aurora A (IC50 = 0.39 M).
价 格：￥电议型 号：T9040产 地：中国大陆
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T6068MK-5108MK 5108,VX689,Aurora Kinase,VX 689,inhibit,Autophagy,MK-5108,Inhibitor
MK-5108 is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value of 0.064 nM.
价 格：￥电议型 号：T6068产 地：中国大陆
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T6435CCT129202inhibit,CCT-129202,CCT 129202,Inhibitor,CCT129202,Aurora Kinase
CCT129202 is an ATP-competitive pan-Aurora inhibitor for Aurora A, Aurora B and Aurora C with IC50 of 0.042 μM, 0.198 μM and 0.227 μM, respectively. It is less potent to FGFR3, GSK3β, PDGFRβ, etc.
价 格：￥电议型 号：T6435产 地：中国大陆
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T6380AMG 900AMG 900,Inhibitor,Aurora Kinase,inhibit
AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM. It is >10-fold selective for Aurora kinases than p38α, Tyk2, JNK2, Met and Tie2. Phase 1.
价 格：￥电议型 号：T6380产 地：中国大陆
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T64338AKI603AKI603,Aurora Kinase,chronic,CML,leukemia,myeloid,inhibit,imatinib-resistant,Inhibitor
AKI603 is a novel small molecule inhibitor of Aurora kinase A (AurA)(IC50 = 12.3 nM). AKI603 is developed to overcome resistance mediated by BCR-ABL-T315I mutation. AKI603 exhibits strong anti-proliferative activity in leukemic cells[1][2].
价 格：￥电议型 号：T64338产 地：中国大陆
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T6785BI-847325BI 847325,inhibit,Apoptosis,MEK,MAPKK,MAP2K,Inhibitor,Aurora Kinase,Mitogen-activated prote
BI-847325 is a selective dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively.
价 格：￥电议型 号：T6785产 地：中国大陆
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T6129GSK-1070916Inhibitor,Aurora Kinase,GSK-1070916,GSK 1070916,Apoptosis,inhibit
GSK1070916 is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 nM. It displays >100-fold selectivity against the closely related Aurora A-TPX2 complex. Phase 1.
价 格：￥电议型 号：T6129产 地：中国大陆
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T6458CYC-116CYC116,inhibit,Inhibitor,CYC-116,CYC 116,Aurora Kinase
CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active against PKA, Akt/PKB, PKC, no effect on GSK-3α/β, CK2, Plk1 and SAPK2A. Phase 1.
价 格：￥电议型 号：T6458产 地：中国大陆
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T6532HesperadinAurora Kinase,Aurora,Autophagy,Parasite,Influenza Virus,Hesperadin,procyclic,forms,bloodst
Hesperadin(IC50=250 nM) effectively inhibits Aurora B. It potently reduces the activity of AMPK, MAPKAP-K1, MKK1, Lck, CHK1 and PHK, but it could not inhibit MKK1 activity in vivo.
价 格：￥电议型 号：T6532产 地：中国大陆
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T2709TAK-901TAK 901,Inhibitor,TAK-901,Aurora Kinase,inhibit
TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among others.
价 格：￥电议型 号：T2709产 地：中国大陆
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T5524Aurora kinase inhibitor-3Aurora Kinase Inhibitor III
Aurora kinase inhibitor III is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR.
价 格：￥电议型 号：T5524产 地：中国大陆
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T5524Aurora Kinase Inhibitor IIIAurora Kinase Inhibitor III
Aurora kinase inhibitor III is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR.
价 格：￥电议型 号：T5524产 地：美洲
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T82931Aurora A inhibitor 3；化合物 Aurora A inhibitor 3Aurora A inhibitor 3
Aurora A Inhibitor 3 (Compound 5h) effectively inhibits Aurora-A kinase, exhibiting an IC50 of 0.78 μM, and demonstrates cytotoxicity against MCF-7 and MDA-MB-231 cell lines with GI50 values of 0.12 μM and 0.63 μM, respectively [1].
价 格：￥电议型 号：T82931产 地：中国大陆
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T78753Aurora Kinases-IN-4；化合物 Aurora Kinases-IN-4Aurora Kinases-IN-4
Aurora Kinases-IN-4 (Compound 11c) is a covalent, ATP-competitive inhibitor of aurora kinase A with an IC50 value of 1.7 nM. It demonstrates cell proliferation inhibition in SJSA-1, MDA-MB-231, A549, and HeLa cell lines with IC50 values of 4.27, 1.54, 3.08, and 6.99 μM, respectively. This compound is applicable in research concerning triple-negative breast cancer (TNBC) [1].
价 格：￥电议型 号：T78753产 地：中国大陆
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T72522Aurora kinase-IN-1；化合物 Aurora kinase-IN-1Aurora kinase-IN-1
Aurora kinase-IN-1, a potent aurora kinase inhibitor, modulates cell cycle progression and induces apoptosis by upregulating G1 cell cycle inhibitory proteins (including p21 and p27), elevating G1 progressive cyclin D1, and downregulating G1-to-S progressive cyclins, thereby arresting the cell cycle at the G1/S boundary. It stands as a promising lead compound for the development of chemotherapeutic agents.
价 格：￥电议型 号：T72522产 地：中国大陆
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T72504Aurora Kinases-IN-3；化合物 Aurora Kinases-IN-3Aurora Kinases-IN-3
Aurora Kinases-IN-3, an orally active inhibitor of AURKB, suppresses AURKB activity by hindering its mitotic localization rather than by inhibiting its phosphorylation of H3 at Ser10.
价 格：￥电议型 号：T72504产 地：中国大陆
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T6767TCS7010；化合物Aurora A Inhibitor IAurora A Inhibitor I；Aurora A Inhibitor I
TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay. It is 1000-fold more selective for Aurora A than Aurora B.
价 格：￥电议型 号：T6767产 地：中国大陆
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T63853Aurora kinase inhibitor-10；化合物 Aurora kinase inhibitor-10Aurora kinase inhibitor-10
Aurora kinase inhibitor-10 is an orally active Aurora B inhibitor (IC50: 8 nM) that exhibits antitumour effects.
价 格：￥电议型 号：T63853产 地：中国大陆
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T63773Aurora kinase inhibitor-8；化合物 Aurora kinase inhibitor-8Aurora kinase inhibitor-8
Aurora kinase inhibitor-8 is a highly selective inhibitor of Aurora kinase.
价 格：￥电议型 号：T63773产 地：中国大陆
