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TP1724LPUMA BH3 acetatePUMA BH-3 acetate,PUMA BH3 acetate
PUMA BH3 acetate is a p53 positive regulator of apoptosis (PUMA) BH3 domain polypeptide that acts as a direct activator of Bak with a Kd of 26 nM.
价 格:¥电议型 号:TP1724L产 地:中国大陆
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T83751PUMA BH3 (human) TFA;化合物 PUMA BH3 (human) TFAPUMA BH3 (human) TFA
PUMA BH3, a peptide that includes the BH3 domain from the p53-upregulated modulator of apoptosis (PUMA) and activates the pro-apoptotic protein Bak, demonstrates binding affinity to Bak with dissociation constants (Kds) of 290 nM in HEPES buffer and 26 nM in CHAPS buffer. This interaction with Bak induces its homo-oligomerization and facilitates Bak-mediated membrane permeabilization.
价 格:¥电议型 号:T83751产 地:中国大陆
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T83114Angiopep-Bim BH3 hydrochloride;化合物 Angiopep-Bim BH3 hydrochlorideAngiopep-Bim BH3 hydrochloride
Angiopep-Bim BH3 hydrochloride, a peptode that penetrates the blood-brain barrier (BBB), may serve as a tool to study the permeability of central nervous system (CNS) therapeutics [1].
价 格:¥电议型 号:T83114产 地:中国大陆
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T80232Hrk BH3;化合物 Hrk BH3Hrk BH3
Hrk BH3, a biologically active peptide comprising the BH3 domain of Hrk, exhibits functionality within cellular processes.
价 格:¥电议型 号:T80232产 地:中国大陆
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T80231Bik BH3;化合物 Bik BH3Bik BH3
Bik BH3, a biologically active peptide derived from the BH3 domain of BIK, exhibits specific functions pertinent to its origin.
价 格:¥电议型 号:T80231产 地:中国大陆
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T80229Noxa B BH3;化合物 Noxa B BH3Noxa B BH3
Noxa B BH3, a biologically active peptide encompassing the BH3 domain of the Noxa protein, displays targeted biological activity.
价 格:¥电议型 号:T80229产 地:中国大陆
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T80228r8-Gly-Noxa A BH3;化合物 r8-Gly-Noxa A BH3r8-Gly-Noxa A BH3
r8-Gly-Noxa A BH3 is a biologically active peptide with cell-permeability, comprising amino acid residues 17 to 36 derived from the BH3 (death) domain of Noxa A. The peptide is modified by the addition of eight D-Arginine residues and a Glycine linker at its amino terminal.
价 格:¥电议型 号:T80228产 地:中国大陆
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T80227Noxa A BH3;化合物 Noxa A BH3Noxa A BH3
Noxa A BH3, a bioactive peptide, encompasses the BH3 domain of the Noxa protein.
价 格:¥电议型 号:T80227产 地:中国大陆
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T80226r8 Bid BH3;化合物 r8 Bid BH3r8 Bid BH3
r8 Bid BH3, a biologically active peptide, is a pro-apoptotic member of the "BH3-only" subset within the BCL-2 family proteins, pivotal in regulating apoptosis. This compound exhibits lethality towards Bcl-2-expressing human leukemia cell lines, indicating its promise as a potential cancer therapeutic. The peptide is conjugated with poly-D-arginine (denoted by rrrrrrrr), enhancing cellular uptake.
价 格:¥电议型 号:T80226产 地:中国大陆
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T80225Bid BH3 (80-99), FAM labeled;化合物 Bid BH3 (80-99), FAM labeledBid BH3 (80-99), FAM labeled
FAM-labeled Bid BH3 (80-99) is a biologically active peptide featuring a 5-FAM label at its N-terminus.
价 格:¥电议型 号:T80225产 地:中国大陆
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T80224Bid BH3 (80-99);化合物 Bid BH3 (80-99)Bid BH3 (80-99)
Bid BH3 (80-99) is a biologically active peptide known as a pro-apoptotic member of the ´BH3-only´ (BOPS) subset within the BCL-2 protein family, pivotal in apoptosis regulation. It notably interacts with Bcl-2, Bax, and Bak, initiating their activation or inactivation, thus inducing cell death. Additionally, Bid translocates from the cytosol to the mitochondrial membrane as part of its functional mechanism. The presence of Pyroglutamyl (pGlu) peptides, which can spontaneously arise
价 格:¥电议型 号:T80224产 地:中国大陆
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T80223Bad BH3 (mouse);化合物 Bad BH3 (mouse)Bad BH3 (mouse)
Bad BH3 (mouse) is a bioactive peptide derived from the BH3 domain (a death domain) of Bad, encompassing amino acid residues 140 to 165, and functions by binding to bcl-2.
价 格:¥电议型 号:T80223产 地:中国大陆
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T80038Bim BH3;化合物 Bim BH3Bim BH3
Bim BH3 is a bioactive peptide that belongs to the pro-apoptotic Bcl-2 family of proteins.
价 格:¥电议型 号:T80038产 地:中国大陆
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T80029Bak BH3 (72-87), TAMRA-labeled;化合物 Bak BH3 (72-87), TAMRA-labeledBak BH3 (72-87), TAMRA-labeled
Bak BH3 (72-87), TAMRA-labeled, is a bioactive peptide.
价 格:¥电议型 号:T80029产 地:中国大陆
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T76543NoxaBH3;化合物 NoxaBH3NoxaBH3
NoxaBH3, a cysteine-based cross-linked peptide, exhibits enhanced cell permeability and greater inhibitory efficacy against Mcl-1. It binds to the endogenous CXCR4 ligand, resulting in the formation of a ubiquitin-NoxaBH3 conjugate that is subsequently delivered to cancer cells [1].
价 格:¥电议型 号:T76543产 地:中国大陆
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T76073BH3 hydrochloride;化合物 BH3 hydrochlorideBH3 hydrochloride
BH3 hydrochloride, a peptide that crosses the blood-brain barrier, induces apoptosis either through direct activation of the pro-apoptotic proteins Bax/Bak or by inhibiting anti-apoptotic Bcl-2 proteins (Bcl-2, Bcl-XL, Bcl-w, Mcl-1, and A-1) through their BH3 domain [1][2].
价 格:¥电议型 号:T76073产 地:中国大陆
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T76030Bim BH3, Peptide IV TFA;化合物 Bim BH3, Peptide IV TFABim BH3, Peptide IV TFA
Bim BH3, Peptide IV TFA, is a 26-residue peptide derived from the BH3-only protein Bim, a member of the pro-apoptotic Bcl-2 protein family [1] [2].
价 格:¥电议型 号:T76030产 地:中国大陆
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T75980PUMA BH3 TFA;化合物 PUMA BH3 TFAPUMA BH3 TFA
PUMA BH3 (TFA), a peptide from the BH3 domain of the p53 upregulated modulator of apoptosis (PUMA), directly activates Bak with a dissociation constant (Kd) of 26 nM [1].
价 格:¥电议型 号:T75980产 地:中国大陆
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T40379Bax BH3 peptide (55-74), wild type;Bax BH3 peptide (55-74), wild typeBax BH3 peptide (55-74), wild t
Bax BH3 peptide (55-74), wild type is a 20-amino acid peptide (Bax 1) known for its ability to induce apoptosis in various cell line models.
价 格:¥电议型 号:T40379产 地:中国大陆