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T9264ECBN HCLInhibitor,inhibit,ECBN HCL,A-30912A nucleus
A-30912A nucleus hydrochloride is the reaction product catalyzed by Echinocandin B (ECB) deacylase.
价 格：￥电议型 号：T9264产 地：中国大陆
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T8824CRBN modulator-1CRBN modulator1,CRBN modulator-1,inhibit,CRBN modulator 1,Ligands for E3 Ligase,E3 l
WUN29654 is a Thalidomide analog and CRBN modulator,has an IC50 of 3.5 μM and a Ki of 0.98 μM.
价 格：￥电议型 号：T8824产 地：中国大陆
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T67844RBN-3143RBN3143
RBN-3143 is a potent and inhibitor of NAD+-competitive catalytic PARP14 (IC50= 4 nM). RBN-3143 inhibits ADP-ribosylation mediated by PARP14 and stabilizes PARP14 in cell lines. RBN-3143 exhibits research potential of lung inflammation.
价 格：￥电议型 号：T67844产 地：中国大陆
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T9907NivolumabNivolumab
Nivolumab anti-PD-1) is a genetically engineered fully human immunoglobulin Ig) G4 monoclonal antibody directed against the negative immunoregulatory human cell surface receptor programmed death-1PD-1PCD-1) with immune checkpoint inhibitory and antineoplastic activities.
价 格：￥电议型 号：T9907产 地：中国大陆
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T9370dCBP-1Inhibitor,p300,multiple,CRBN,myeloma,cell,degrader,PROTACs,MYC,CBP,inhibit,dCBP 1,dCBP1,hetero
dCBP-1 is a chemical degrader of p300/CBP. dCBP-1 hijacks the E3 ubiquitin ligase CRBN for selective degradation of p300/CBP. Degradation of p300/CBP by dCBP-1 leads to effective multiple myeloma cell killing.
价 格：￥电议型 号：T9370产 地：中国大陆
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T9291Thalidomide-5-OHLigands for E3 Ligase,PROTAC,Inhibitor,Thalidomide5OH,inhibit,CRBN,E3 ligase-recruit
Thalidomide-5-OH is the Thalidomide-based cereblon ligand that used in the recruitment of CRBN protein. It can be connected to the ligand for protein by a linker to form PROTAC.
价 格：￥电议型 号：T9291产 地：中国大陆
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T6614Nutlin-3bNutlin 3b,Inhibitor,MDM-2/p53,Ubiquitin activating enzyme,Ubiquitin conjugating enzyme,inhi
Nutlin-3b is a p53/MDM2 antagonist or inhibitor (IC50: 13.6 μM), 150-fold less potent (+)-enantiomer of Nutlin-3 as in comparison with opposite (-)-enantiomer Nutlin-3a.
价 格：￥电议型 号：T6614产 地：中国大陆
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T4671BN82002CDC25C,BN82002,CDC25A,BN-82002,inhibit,CDC25B3,MIA PaCa-2,Inhibitor,CDC25B2,BN 82002,Phosphat
BN82002 is a synthetic inhibitor of CDC25 phophatases
价 格：￥电议型 号：T4671产 地：中国大陆
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T7030anemarsaponin BNF-κB,Nuclear factor-kappaB,COX,MAP2K,anemarsaponin B,Mitogen-activated protein kinas
Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity, possibly via the p38 MAP kinase pathway. Anemarsaponin B can inhibit PAF-induced rabbit platelet aggregation in vitro.
价 格：￥电议型 号：T7030产 地：中国大陆
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T9168NSC 617145NSC 617145,breaks,NHEJ,helicase,DSB,abnormalities,WRN,DNA/RNA Synthesis,strand,Rad51,chrom
NSC617145 is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependent manner.
价 格：￥电议型 号：T9168产 地：中国大陆
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T7791IberdomideCELMoD,H929,CRBN,Ligands for E3 Ligase,KMS12PE,KMS11,orally,sub-G1,Apoptosis,Iberdomide,ce
Iberdomide is a modulator of cereblon( IC50 value of 60 nM in a competitive TR-FRET assay).
价 格：￥电议型 号：T7791产 地：中国大陆
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T33513MSBNMSBN
MSBN is a highly selective fluorescent probe for mercaptans that can selectively image mercaptans in living cells and specifically label protein mercaptans by switching on the signal to identify various reversible protein mercaptans modifications.
价 格：￥电议型 号：T33513产 地：中国大陆
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T60099RBN013209RBN013209
RBN013209 is a potent CD38 inhibitor. RBN013209 is useful in the treatment of cancer.
价 格：￥电议型 号：T60099产 地：中国大陆
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T8318BNC210GAD,generalised anxiety disorder,Inhibitor,BNC 210,inhibit,BNC-210,nAChR,IW2143,IW 2143,Nicoti
BNC210 is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression.
价 格：￥电议型 号：T8318产 地：中国大陆
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T7638NPPBNPPB,Cl? Channels,Chloride Channel,inhibit,Inhibitor
NPPB is a chloride channel blocker with IC50 of 80 nM .
价 格：￥电议型 号：T7638产 地：中国大陆
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T9408N-piperidine IbrutinibN piperidine Ibrutinib,Npiperidine Ibrutinib
N-piperidine Ibrutinib is a potent BTK inhibitor with IC50s of 51.0 for WT BTK and 30.7 nM for C481S BTK respectively. N-piperidine Ibrutinib can be used as a BTK ligand in the synthesis of a series of PROTACs, such as SJF620. SJF620 is a potent PROTAC BTK degrader with a DC50 of 7.9 nM.
价 格：￥电议型 号：T9408产 地：中国大陆
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T6247OnvansertibNMS-P937；NMS-1286937
NMS-P937 (NMS1286937), an oral, specific Polo-like Kinase 1 (PLK1) inhibitor, is with IC50 of 2 nM. The specificity of NMS-P937 forPLK1 is 5000-fold higher over PLK2/PLK3.
价 格：￥电议型 号：T6247产 地：中国大陆
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T6184OrantinibNSC 702827；SU6668；TSU-68
TSU-68, a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation. It shows little effect against IGF-1R, Met, Src, Lck, Zap70, Abl and CDK2 and does not suppresses EGFR.
价 格：￥电议型 号：T6184产 地：中国大陆
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T6131PimasertibN-[(2S)-2,3-二羟基丙基]-3-[(2-氟-4-碘苯基)氨基]-4-吡啶甲酰胺；MSC1936369B；AS703026；SAR 245509
Pimasertib is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity.
价 格：￥电议型 号：T6131产 地：中国大陆
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T5149MC-Val-Cit-PABN-[6-(2,5-二氢-2,5-二氧代-1H-吡咯-1-基)-1-氧代己基]-L-缬氨酰-N5-(氨基甲酰基)-N-[4-(羟甲基)苯基]-L-鸟氨酰胺
MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. FDA approved drugs such as brentuximab vedotin use this linker.
价 格：￥电议型 号：T5149产 地：中国大陆
