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产品数:86101
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T4074GSK-872translocation,GSK-872,neurological,HMGB1,Receptor-interacting protein kinases,brain,GSK 872,c
GSK872 (GSK2399872A) is an effective and specific RIP3 kinase inhibitor. It binds RIP3 kinase domain with high affinity (IC50: 1.8 nM) and inhibits kinase activity (IC50: 1.3 nM).
价 格:¥电议型 号:T4074产 地:中国大陆
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T9146ms48107Inhibitor,GPR68,GPCR,MS 48107,ms48107,brain-penetrant,BBB,inhibit,5-HT2B,MS-48107,bioavailabl
MS48107 is a potent and selective positive allosteric modulator of G protein-coupled receptor 68 (GPR68). It is selective for GPR68 over the closely related proton GPCRs, neurotransmitter transporters, and hERG ion channels. It can readily cross the blood-brain barrier (BBB) in mice.
价 格:¥电议型 号:T9146产 地:中国大陆
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T9346CVN424penetrant,CVN 424,GPR6,inhibit,orally,CVN424,brain,Inhibitor,Parkinson,CVN-424,disease
CVN424 is a selective and novel GPR6 Inverse agonist effective in models of Parkinson Disease.
价 格:¥电议型 号:T9346产 地:中国大陆
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T7558CID-1067700ML282,competitively,CID1067700,brain,Rab7,ML 282,GTPase,Ras,machinery,Ras-related,CID-106
CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases(Rab7 with a Ki of 13 nM).
价 格:¥电议型 号:T7558产 地:中国大陆
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T21747VU0483605Inhibitor,inhibit,VU0483605,Metabotropic glutamate receptors,allosteric modulator,brain pen
VU0483605 is an effective and selective positive allosteric modulator of mGluR1 with EC50s of 390 and 356 nM for human and rat, respectively.
价 格:¥电议型 号:T21747产 地:中国大陆
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TN7044S-(4-Hydroxybenzyl)glutathioneS (4 Hydroxybenzyl)glutathione,inhibit,glutamate,brain,kainic,acid,Inh
L-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia elata.
价 格:¥电议型 号:TN7044产 地:中国大陆
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T8778TTK21TTK 21,HAT,histone acetyltransferases,neurogenesis,TTK21,blood–brain barrier,HATs,inhibit,Histo
TTK21 is an activator of CBP/p300 histone acetyltransferase activity.
价 格:¥电议型 号:T8778产 地:中国大陆
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T6595Moexipril hydrochlorideorally active,Apoptosis,Ischemic brain injury,inhibit,hepatic disease,RS10085
Moexipril HCl is a potent orally active nonsulfhydrylangiotensin converting enzyme (ACE)inhibitor, used for the treatment of hypertension and congestive heart failure.
价 格:¥电议型 号:T6595产 地:中国大陆
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T9697ASK1-IN-1CNS,inhibit,p38 MAPK,ASK1,ASK-1-IN-1,ASK1 IN 1,ASK1IN1,MAPK,Inhibitor,brain,penetrant
ASK1-IN-1 is an inhibitor of apoptosis signal-regulating kinase 1 which is a key mediator in the apoptotic and inflammatory cellular stress response with an IC50 of 21 nM in biochemica assays.
价 格:¥电议型 号:T9697产 地:中国大陆
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T9466RTICBM-189Brain,Inhibitor,RTICBM-189,inhibit,Cocaine,RTICBM 189,Allosteric,Penetrant,Cannabinoid Rec
RTICBM-189 is Brain Penetrant and Attenuates Reinstatement of Cocaine-Seeking Behavior.
价 格:¥电议型 号:T9466产 地:中国大陆
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T7530PD146176inhibit,tau,brain,triple,NSC-168807,PD146176,Autophagy,pathology,amyloidosis,transgenic,reti
PD146176 is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM. PD146176 reverses cognitive impairment, brain amyloidosis, and tau pathology by stimulating autophagy in aged triple transgenic mice.
价 格:¥电议型 号:T7530产 地:中国大陆
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T6504Flupirtine maleatecentrally,acting,brain,?penetrant,Flupirtine maleate,KcsA,Flupirtine,Neuroprotecti
Flupirtine maleate, a centrally acting non-opioid analgesia, is the salt form of Flupirtine. It is an NMDA receptor antagonist , and also a specific neuronal potassium channel opener.
价 格:¥电议型 号:T6504产 地:中国大陆
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T9232Mitochondrial fusion promoter M1Mitochondrial Metabolism,ischemia,cardiac,inhibit,brain,damage,injur
Mitochondrial fusion promoter M1 is a mitochondrial dynamic modulator. Mitochondrial fusion promoter M1 preserves the mitochondrial function and promotes cellular respiration. Mitochondrial fusion promoter M1 alleviates brain and cardiac damage in rats with cardiac ischemia/reperfusion injury.
价 格:¥电议型 号:T9232产 地:中国大陆
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TP1264Prolylleucinedisorders,Inhibitor,Prolylleucine,circadian,inhibit,motility,brain ,systems,peptidergic
Prolylleucine is a dipeptide containing branched-chain amino acids.
价 格:¥电议型 号:TP1264产 地:中国大陆
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T7601LCarbetocin acetateCarbetocin,Carbetocin acetate,inhibit,hemorrhage,blood-brain,barrier,Inhibitor,ant
Carbetocin acetate is an obstetric drug used to control postpartum hemorrhage and bleeding after giving birth.
价 格:¥电议型 号:T7601L产 地:中国大陆
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T9452PW0787GPR52,PW-0787,oral,PW0787,Inhibitor,PW 0787,brain-penetrant,selective,inhibit,psychostimulant,
PW0787 is a potent, selective, orally active, and brain-penetrant GPR52 agonist (EC50=135 nM).
价 格:¥电议型 号:T9452产 地:中国大陆
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T83905Brain Natriuretic Peptide-32 (rat) acetate;化合物 Brain Natriuretic Peptide-32 (rat) acetateBNP (14-45)
Brain natriuretic peptide-32 (BNP-32), a fragment of the proBNP cardiovascular hormone precursor, exhibits affinity for natriuretic peptide receptors in rat vascular smooth muscle cells (IC50 = 7.3 nM) and promotes cGMP accumulation within these cells (EC50 = 170 nM). Additionally, BNP-32 effectively mediates the relaxation of norepinephrine-precontracted isolated rat aortic strips (EC50 = 6.7 nM). Upon administration at a dosage of 3 ?g/kg, it elevates urine and urinary electrolyte outputs and
价 格:¥电议型 号:T83905产 地:中国大陆
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T82823Brain Natriuretic Peptide-45, rat TFA;化合物 Brain Natriuretic Peptide-45, rat TFABNP-45, rat TFA;BNP-4
Brain Natriuretic Peptide-45, rat TFA (BNP-45, rat TFA) is an isoform of rat brain natriuretic peptide extracted from rat heart, exhibiting significant hypotensive and natriuretic effects [1].
价 格:¥电议型 号:T82823产 地:中国大陆
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T76321Brain Derived Basic Fibroblast Growth Factor (1-24);化合物 Brain Derived Basic Fibroblast Growth Factor
Brain Derived Basic Fibroblast Growth Factor (1-24) (FGF basic 1-24), a synthetic peptide, exhibits anti-bacterial and anti-HBV properties, finding application in infectious and immune disease research [1].
价 格:¥电议型 号:T76321产 地:中国大陆
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T39246Brain Natriuretic Peptide-45, mouse;Brain Natriuretic Peptide-45, mouseBrain Natriuretic Peptide-45,
Mouse Brain Natriuretic Peptide-45 (BNP-45, mouse) is a circulating variant of the mouse brain natriuretic peptide derived from the mouse heart. It exhibits powerful hypotensive and natriuretic properties.
价 格:¥电议型 号:T39246产 地:中国大陆