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T79674HDAC-IN-64；化合物 HDAC-IN-64HDAC-IN-64
HDAC-IN-64 (Compound 13), an HDAC inhibitor, demonstrates potent inhibition of HDAC4/5/6/7/9 with IC50 values of 24, 45, 85, 31, and 37 nM, respectively. It exhibits anti-proliferative and anti-migration effects on prostate cancer (PCA) cells, specifically inhibiting the growth of LNCaP and RWPE-1 cells with GI50 values of 0.32 and 1.1 μM, respectively [1].
价 格：￥电议型 号：T79674产 地：中国大陆
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T79541HDAC-IN-61；化合物 HDAC-IN-61HDAC-IN-61
HDAC-IN-61 (compound 12k) is a potent, orally active inhibitor of histone deacetylase (HDAC) with anticancer activity, exhibiting an IC50 of 30 nM against Bel-7402 cells, and is utilized for cancer research [1].
价 格：￥电议型 号：T79541产 地：中国大陆
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T79496Cathepsin C-IN-6；化合物 Cathepsin C-IN-6Cathepsin C-IN-6
Cathepsin C-IN-6 (compound 2), an E-64c-hydrazideas-derived inhibitor of cathepsin C, possesses anti-inflammatory properties and impedes neutrophil elastase activation. This compound demonstrates potential efficacy in treating inflammatory diseases characterized by elevated neutrophil counts, such as chronic obstructive pulmonary disease (COPD) [1].
价 格：￥电议型 号：T79496产 地：中国大陆
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T79371HDAC-IN-62；化合物 HDAC-IN-62HDAC-IN-62
HDAC-IN-62 (Compound 5), an HDAC inhibitor, exhibits IC50 values of 0.78, 1.0, and 1.2 μM for HDAC6, HDAC8, and HDAC11, respectively. This compound suppresses microglial activation via autophagy induction and reduces nitric oxide production, demonstrating anti-inflammatory and antidepressant properties. Additionally, HDAC-IN-62 has been shown to inhibit microglial activation in mouse brains [1].
价 格：￥电议型 号：T79371产 地：中国大陆
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T78818HDAC-IN-63；化合物 HDAC-IN-63HDAC-IN-63
HDAC-IN-63 (Compound 63) is a dual FLT3/HDAC inhibitor with IC50 values of 0.844 nM for FLT3 and 30.0 nM for HDAC1. It effectively suppresses MV4-11 cell proliferation with an IC50 of 92 nM, induces apoptosis, and arrests the cell cycle in MV4-11 cells. This compound is applied in acute myeloid leukemia (AML) research [1].
价 格：￥电议型 号：T78818产 地：中国大陆
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T78767HDAC-IN-60；化合物 HDAC-IN-60HDAC-IN-60
HDAC-IN-60 (compound 21a), a potent histone deacetylase (HDAC) inhibitor, promotes intracellular reactive oxygen species (ROS) production, induces DNA damage, arrests the cell cycle at the G2/M phase, and triggers mitochondria-related apoptotic pathways, leading to cell apoptosis [1].
价 格：￥电议型 号：T78767产 地：中国大陆
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T72012HDAC-IN-6；化合物 HDAC-IN-6HDAC-IN-6
HDAC-IN-6 is an HDAC inhibitor, targeting HDAC2, HDAC3, HDAC4, HDAC5, HDAC7, HDAC8, and HDAC9.
价 格：￥电议型 号：T72012产 地：中国大陆
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T28940Tec-IN-6；化合物 T28940Tec Inhibitor-6；Tec Inhibitor-6
Tec-IN-6 is an inhibitor of Tec kinase, it also blocks unconventional secretion of fibroblast growth factor 2 (FGF2).
价 格：￥电议型 号：T28940产 地：中国大陆
