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T6908NSC 228155Epidermal growth factor receptor,Histone Acetyltransferase,EGFR,HER1,HATs,inhibit,Inhibito
NSC228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.
价 格:¥电议型 号:T6908产 地:中国大陆
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T7846Aegelineαsyn,Aegeline,yeast,Inhibitor,protein,Sec22p,inhibit,toxicity,Fungal,SNARE
Aegeline is an alkaloidal-amide, isolated from the leaves of Aegle marmelos and have shown antihyperglycemic as well as antidyslipidemic activities in the validated animal models of type 2 diabetes mellitus.
价 格:¥电议型 号:T7846产 地:中国大陆
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T9698UC2288Attenuator,786-O,Inhibitor,UC-2288,MDM-2/p53,inhibit,UC2288,ovarian,RCC,HK2,UC 2288,p21,sorafe
UC2288 is a relatively selective p21 attenuator which is synthesized based Sorafenib. UC2288 attenuates p21 protein levels with minimal effect on p21 protein stability.
价 格:¥电议型 号:T9698产 地:中国大陆
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T6875LesinuradRDEA 594,RDEA-594,SLC22A12,Inhibitor,Lesinurad,inhibit,URAT1,Urate transporter 1
Lesinurad is a selective inhibitor of uric acid reabsorption which is used in combination with other agents in the therapy of gout. Lesinurad has had a limited clinical use but has not been associated with serum enzyme elevations during therapy or with instances of clinically apparent liver injury.
价 格:¥电议型 号:T6875产 地:中国大陆
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T3351OnatasertibCC-223;CC 223;CC223
CC-223 is an orally available mTOR inhibitor with potential antitumor activity. CC-223 inhibits the activity of mTOR, which may result in the induction of tumor cell apoptosis and a decrease in tumor cell proliferation. CC-223 is a potent mTOR kinase inhi
价 格:¥电议型 号:T3351产 地:中国大陆
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T20741Lilial铃兰醛;NSC-22275;NSC22275;Lilyal;NSC 22275
Lilial (a trade name for lily aldehyde, also known as lysmeral) is a chemical compound commonly used as a perfume in cosmetic preparations and laundry powders, often under the name butylphenyl methylpropional. It is a synthetic aromatic aldehyde.Lilial is
价 格:¥电议型 号:T20741产 地:中国大陆
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T2066Quizartinib奎扎替尼;AC220
Quizartinib is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases.
价 格:¥电议型 号:T2066产 地:中国大陆
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T201028-Azahypoxanthine阿扎次黄嘌呤;NSC-22709;NSC22709;NSC 22709
8-Azahypoxanthine inhibits hypoxanthine-guanine-xanthine phosphoribosyltransferase and has antimalarial properties.
价 格:¥电议型 号:T20102产 地:中国大陆
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T19759NSC-226572Methyiin, pyrolyzate;NSC 226572;NSC226572;S-甲基-L-半胱氨酸亚砜
NSC-226572 is a synthetic analog of alliin found in cruciferous vegetables including cabbage, turnip, cauliflower, and kale. NSC-226572 is converted through alliinase activity into a volatile thiosulfinate.
价 格:¥电议型 号:T19759产 地:中国大陆
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T1968UNC2250
UNC2250 is an effective and specific Mer inhibitor (IC50=1.7 nM).
价 格:¥电议型 号:T1968产 地:中国大陆
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T2066QuizartinibQuizartinib,AC220,
Quizartinib is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases.
价 格:¥电议型 号:T2066产 地:美洲
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T73397ENT-C225;化合物 ENT-C225ENT-C225
ENT-C225 is a potent TrkB neurotrophin receptor (TrkBR) activator with neuroprotective activity for the study of Alzheimer´s disease and Parkinson´s disease.
价 格:¥电议型 号:T73397产 地:中国大陆
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T6908NSC 228155化合物NSC228155NSC228155
NSC 228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.
价 格:¥电议型 号:T6908产 地:中国大陆
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T63380IDH-C227;化合物 IDH-C227IDH-C227
IDH-C227 is a selective and potent inhibitor of IDH1R132H that exhibits anticancer activity.
价 格:¥电议型 号:T63380产 地:中国大陆
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T38282C22 Glucosylceramide (d18:1/22:0);C22 Glucosylceramide (d18:1/22:0)C22 Glucosylceramide (d18:1/22:0)
C22 Glucosylceramide (d18:1/22:0) is an endogenous glucosylceramide. Glucosylceramides are major constituents of skin lipid membranes where they play a role in maintaining the water permeability barrier. They are precursors in the synthesis of lactosylceramide , as well as oligoglycolipids and gangliosides. Phospholipase A2 (PLA2) type XIIA knockdown increases C22 glucosylceramide (d18:1/22:0) expression in rat brain. It is also increased in the brain, but not the liver or spinal cord, of mice f
价 格:¥电议型 号:T38282产 地:中国大陆
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T38281C22 Galactosylceramide (d18:1/22:0);C22 Galactosylceramide (d18:1/22:0)C22 Galactosylceramide (d18:1
C22 Galactosylceramide is a sphingolipid that has been found in the central nervous system.1,2C22 Galactosylceramide levels are increased in the spinal cord, but not the brain or liver, of mice fed a methionine-restricted diet.1C22 Galactosylceramide has been found in postmortem hippocampus from patients with Alzheimer´s disease.2[Matreya, LLC.]
价 格:¥电议型 号:T38281产 地:中国大陆
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T38280C22 dihydro 1-Deoxyceramide (m18:0/22:0);C22 dihydro 1-Deoxyceramide (m18:0/22:0)C22 dihydro 1-Deoxy
C22 dihydro 1-Deoxyceramide (m18:0/22:0) is a very long-chain atypical ceramide containing a 1-deoxysphinganine backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2 C22 dihydro 1-Deoxyceramide (m18:0/22:0) has been found in mouse embryonic fibroblasts (MEFs) following application of 1-deoxysphinganine alkyne or 1-deoxysphinganine-d3.3 It has also been found as the most prevalent dihydro
价 格:¥电议型 号:T38280产 地:中国大陆
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T37563C22 Ceramide (d18:1/22:0);C22神经酰胺(d18:1/22:0)Cer(d18:1/22:0)|||C22 Ceramide|||Ceramide (d18:1/22:0);
C22 Ceramide (d18:1/22:0) (C22 Ceramide), a long-chain ceramide containing behenic acid, is an endogenous bioactive sphingolipid.C22-Ceramide specifically inhibits MCSR and reduces C16 ceramide channel formation in isolated rat liver mitochondria and liposomes.
价 格:¥电议型 号:T37563产 地:中国大陆
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T36860C22 Sphingomyelin (d18:1/22:0);C22 Sphingomyelin (d18:1/22:0)C22 Sphingomyelin (d18:1/22:0);C22 Sphi
C22 Sphingomyelin is a naturally occurring form of sphingomyelin . Plasma levels of C22 sphingomyelin positively correlate with hepatic steatosis severity in patients with chronic hepatitis C virus (HCV). C22 Sphingomyelin levels are decreased in T-47D mammary epithelial cells and increased in MDA-MB-231 breast cancer cells relative to C16 sphingomyelin .
价 格:¥电议型 号:T36860产 地:中国大陆
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T35775HT-2 Toxin-13C22;HT-2 Toxin-13C22HT-2 Toxin-13C22;HT-2 Toxin-13C22
HT-2 toxin-13C22is intended for use as an internal standard for the quantification of HT-2 toxin by GC- or LC-MS. HT-2 toxin is a type A trichothecene mycotoxin and an active, deacetylated metabolite of the trichothecene mycotoxin T-2 toxin .1,2Like T-2 toxin, HT-2 toxin inhibits protein synthesis and cell proliferation in plants.2HT-2 toxin also reduces viability of HepG2, A549, HEp-2, Caco-2, A-204, U937, Jurkat, and RPMI-8226 cancer cells with IC50values ranging from 3.1 to 23 ng/ml and human
价 格:¥电议型 号:T35775产 地:中国大陆