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T62468CB1/2 agonist 1;化合物 CB1/2 agonist 1CB1/2 agonist 1
CB1/2 agonist 1 is a potent CB1/2 agonist that crosses the blood-brain barrier, acting on CB1R (EC50: 56.15 nM) and CB2R (EC50: 11.63 nM). CB1/2 agonist 1 reduces glutamate release and LPS-induced microglia activation, and has anti-inflammatory and analgesic activities. CB1/2 agonist 1 has potential for multiple sclerosis studies.
价 格:¥电议型 号:T62468产 地:中国大陆
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T62411CB1/2 agonist 4;化合物 CB1/2 agonist 4CB1/2 agonist 4
CB1/2 agonist 4 (compound 24) is a CB1 full agonist (EC50: 15.09 nM) and a CB2 partial agonist (EC50: 1.16 nM). CB1/2 agonist 4 has significant anti-harm-sensing activity and also activates cannabinoid and TRPV1 receptors (IC50: 0.8 μM, EC50: 0.12 μM). , EC50: 0.12 μM).
价 格:¥电议型 号:T62411产 地:中国大陆
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T62180CB1/2 agonist 2;化合物 CB1/2 agonist 2CB1/2 agonist 2
CB1/2 agonist 2 (compound 23) is a potent non-selective cannabinoid ligand with Ki of 3.5 nM and 1.2 nM, respectively. CB1/2 agonist 2 is a full agonist of CB1 and a competitive inverse agonist of CB2. BACE-IN-1 is a complete agonist of CB1 and a competitive inverse agonist of CB2.
价 格:¥电议型 号:T62180产 地:中国大陆
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T61736CB1/2 agonist 3;化合物 CB1/2 agonist 3CB1/2 agonist 3
CB1/2 agonist 3 (compound 52), a potent non-selective cannabinoid ligand, is a competitive agonist for the CB1/CB2 receptors. It exhibits CB1/CB2 agonistic activity by binding to the human CB1 and CB2 receptors, with Ki values of 5.9 nM and 3.5 nM, respectively [1].
价 格:¥电议型 号:T61736产 地:中国大陆