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T72388CBB1007 hydrochloride;化合物 CBB1007 hydrochlorideCBB1007 hydrochloride
CBB1007 HCl is a cell-permeable amidino-guanidinium compound identified as a potent, reversible, and substrate-competitive inhibitor of LSD1 (IC50 = 5.27 μM for hLSD1). It effectively inhibits LSD1-mediated demethylation of H3K4Me2 and H3K4Me (IC50 ≤ 5 μM), without affecting H3K4Me3 and H3K9Me2 demethylation, nor the activities of LSD2 and JARID1A. Moreover, CBB1007 increases the levels of H3K4Me2 and H3K4Me (IC50 ≤ 5 μM) and activates epigenetically suppressed genes CHRM4/M4-ArchR and SCN3A in
价 格:¥电议型 号:T72388产 地:中国大陆
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T72244CBB1007 trihydrochloride;化合物 CBB1007 trihydrochlorideCBB1007 trihydrochloride
CBB1007 trihydrochloride is a cell-permeable amidino-guanidinium compound that acts as a potent, reversible and substrate competitive LSD1 selective inhibitor (IC50 = 5.27 μM for hLSD1). IC50 Value: 5.27 uM Target: hLSD1 CBB1007 efficiently can block LSD1-mediated demethylation of H3K4Me2 and H3K4Me (IC50 ≤ 5 μM) with no effect on H3K4Me3 and H3K9Me2, and LSD2 and JARID1A activities. Increases H3K4Me2 and H3K4Me contents (IC50 ≤ 5 μM), and causes activation of epigenetically suppressed
价 格:¥电议型 号:T72244产 地:中国大陆
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T10699L2CBB1007 trihydrochloride (1379573-92-8 free base);化合物 T10699L2CBB1007 trihydrochloride;CBB1007 trihy
CBB1007 trihydrochloride is a selective, reversible, and substrate competitive LSD1 inhibitor (IC50: 5.27 μM for hLSD1).
价 格:¥电议型 号:T10699L2产 地:中国大陆
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T10699LCBB1007;化合物 T10699LCBB1007
CBB1007 is a potent, reversible, and substrate competitive LSD1 inhibitor (IC50: 5.27 μM for hLSD1).
价 格:¥电议型 号:T10699L产 地:中国大陆
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T10699CBB1007 hydrochloride (1379573-92-8 free base);化合物 T10699CBB1007 hydrochloride;CBB1007 hydrochloride
CBB1007 Hcl is a selective, reversible, and substrate competitive LSD1 inhibitor (IC50: 5.27 μM for hLSD1).
价 格:¥电议型 号:T10699产 地:中国大陆