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T38332Complement factor D-IN-2
Complement factor D-IN-2 is an inhibitor of Complement factor D and reduces the excessive activation of complement factor D.
价 格：￥电议型 号：T38332产 地：中国大陆
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T81669NKG2D-IN-2；化合物 NKG2D-IN-2NKG2D-IN-2
NKG2D-IN-2 (compound 47) is an inhibitor of the natural killer group 2D receptor (NKG2D), demonstrating half-maximal inhibitory concentrations (IC50s) of 0.1 ?M for NKG2D/MICA and 0.2 ?M for ULBP6 in time-resolved fluorescence resonance energy transfer (TR-FRET) assays [1].
价 格：￥电议型 号：T81669产 地：中国大陆
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T79798PHD-IN-2；化合物 PHD-IN-2PHD-IN-2
PHD-IN-2 (Compound 91), a potent PHD antagonist with an IC50 of less than 5 nM, effectively stimulates erythropoietin synthesis in HEP3B cells with an EC50 of less than 2.5 μM. It is applicable for research purposes across various medical fields, including cardiovascular, metabolic, hematological, pulmonary, kidney, liver, and wound healing disorders, as well as cancer [1].
价 格：￥电议型 号：T79798产 地：中国大陆
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T72888YAP-TEAD-IN-2；化合物 YAP-TEAD-IN-2YAP-TEAD-IN-2
YAP-TEAD-IN-2 (compound 6) serves as a potent inhibitor of the YAP-TEAD protein-protein interaction (PPI), demonstrating an inhibitory concentration 50 (IC50) value of 2.7 nM [1].
价 格：￥电议型 号：T72888产 地：中国大陆
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T71997CypD-IN-29；化合物 CypD-IN-29CypD-IN-29
CypD-IN-29 is a non-peptidic inhibitor of cyclophilin D as a neuroprotective agent in Aβ-induced mitochondrial dysfunction.
价 格：￥电议型 号：T71997产 地：中国大陆
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T63629PDGFRα/FLT3-ITD-IN-2；化合物 PDGFRα/FLT3-ITD-IN-2PDGFRα/FLT3-ITD-IN-2
PDGFRα/FLT3-ITD-IN-2 is a potent inhibitor of PDGFRα (IC50>20 μM) and FLT3 (IC50: 0.004 μM). PDGFRα/FLT3-ITD-IN-2 has shown investigational potential in acute myeloid leukemia or chronic eosinophilic leukemia.
价 格：￥电议型 号：T63629产 地：中国大陆
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T63274FLT3/ITD-IN-2；化合物 FLT3/ITD-IN-2FLT3/ITD-IN-2
FLT3/ITD-IN-2 is a potent inhibitor of FLT3-ITD and is able to act on FLT3D835Y (IC50: 0.3 nM), FLT3 (IC50: 0.4 nM) and FLT3-ITD (IC50: 1.0 nM).FLT3/ITD-IN-2 effectively inhibits the phosphorylation of FLT3 and is able to effectively inhibit the proliferation of acute myeloid leukemia cells.
价 格：￥电议型 号：T63274产 地：中国大陆
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T61776TEAD-IN-2；化合物 TEAD-IN-2TEAD-IN-2
TEAD-IN-2 is an innovative, orally bioavailable inhibitor that targets the transcriptional enhancer associate domain (TEAD). It functions by regulating TEAD through ubiquitination and/or degradation by specific compounds. This compound, TEAD-IN-2, holds potential for studying various diseases, disorders, or conditions linked to TEAD [1].
价 格：￥电议型 号：T61776产 地：中国大陆
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T61458HIF-PHD-IN-2；化合物 HIF-PHD-IN-2HIF-PHD-IN-2
HIF-PHD-IN-2 (compound 25) is a highly effective PHD inhibitor, displaying IC50 values below 100 nM for PHD1, PHD2, and PHD3 [1].
价 格：￥电议型 号：T61458产 地：中国大陆
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T38332Complement factor D-IN-2；化合物Complement factor D-IN-2Complement factor D-IN-2
Complement factor D-IN-2 is an inhibitor of Complement factor D and reduces the excessive activation of complement factor D.
价 格：￥电议型 号：T38332产 地：中国大陆
