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产品数:86101
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T8873BractoppinDNA break,Bractoppin,phosphopeptide,inhibit,DNA/RNA Synthesis,DNA damage,RAD51,G2 arrest,I
Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibits substrate binding with nanomolar potency in vitro. Structure-activity exploration suggests that Bractoppin engages BRCA1 tBRCT residues recognizing pSer in the consensus motif, pSer-Pro-Thr-Phe, plus an abutting hydrophobic pocket that is distinct in structurally related BRCT domains, conferring selectivity.
价 格:¥电议型 号:T8873产 地:中国大陆
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T6972RS-1RAD51,RS1,RS-1,inhibit,Inhibitor,RS 1,CRISPR/Cas9
RS-1 is a RAD51 activator. RS-1 also increases CRISPR/Cas9-mediated knock-in efficiencies.
价 格:¥电议型 号:T6972产 地:中国大陆
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T9271RAD51-IN-1cancer,inhibit,tumor cell,chemotherapy,RAD51 IN 1,Inhibitor,RAD51,DNA damage,RAD-51-IN-1,R
Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.
价 格:¥电议型 号:T9271产 地:中国大陆
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T9023AtuliflaponInhibitor,inhibit,FLAP,AZD-5718,AZD 5718,artery,Atuliflapon,disease,Coronary,5-LO activat
AZD5718 is a novel 5-Lipoxygenase Activating Protein(FLAP) inhibitor for Treatment of Coronary Artery Disease.
价 格:¥电议型 号:T9023产 地:中国大陆
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T22552LAD57AD57
AD57 is a potent inhibitor of both c-Src and Abl with IC50 of 0.025 μM and 0.041 μM, respectively.
价 格:¥电议型 号:T22552L产 地:中国大陆
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T7382NBD-557HIV,NBD557,NBD 557,NBD-557,inhibit,Human immunodeficiency virus,Inhibitor
NBD-557 is a potentially HIV-1 inhibitor.
价 格:¥电议型 号:T7382产 地:中国大陆
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T35528LTD52 dihydrochloride
TD52 dihydrochloride, an Erlotinib derivative, is an orally active, potent cancerous inhibitor of protein phosphatase 2A (CIP2A) inhibitor. TD52 dihydrochloride mediates the apoptotic effect in triple-negative breast cancer (TNBC) cells via regulating the CIP2A/PP2A/p-Akt signalling pathway. TD52 dihydrochloride indirectly reduced CIP2A by disturbing Elk1 binding to the CIP2A promoter. TD52 dihydrochloride has less p-EGFR inhibition and has potent anti-cancer activity.
价 格:¥电议型 号:T35528L产 地:中国大陆
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T22667CID 5951923Krüppel-like factor,CID-5951923,CID5951923,KLF5,inhibit,cancer,factor,KLF,transcription,I
CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.
价 格:¥电议型 号:T22667产 地:中国大陆
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TN2865(E)-3,4,5-Trimethoxycinnamic acid5-HT Receptor,Inhibitor,Gamma-aminobutyric acid Receptor,sedative,5
(E)-3,4,5-Trimethoxycinnamic acid is a natural product from the roots and rhizomes of Notopterygium incisum.
价 格:¥电议型 号:TN2865产 地:中国大陆
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T8647BCH001PARN,dyskeratosis,telomerase,stem,BCH 001,polynucleotide,TERC,rPAPD5,ncRNA,BCH001,polymerases,
BCH001 is a specific small-molecule inhibitor of PAPD5.
价 格:¥电议型 号:T8647产 地:中国大陆
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TN12965-Feruloylquinic acid5-Feruloylquinic acid,5 Feruloylquinic acid,inhibit,Tyrosinase,5Feruloylquinic
5-O-Feruloylquinic acid is a potent Sirt1 agonist, it is a potential lead compound that can be further tested in drug development process for diseases associated with aging.
价 格:¥电议型 号:TN1296产 地:中国大陆
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T94215-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid5(5Flu
5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid is a chemical compound.
价 格:¥电议型 号:T9421产 地:中国大陆
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T8334CADD522inhibit,MDA-231,Inhibitor,Reactive Oxygen Species,CADD 522,MCF7,MDA-468,breast cancer,CADD522
CADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding with an IC50 of 10 nM, with antitumor activity
价 格:¥电议型 号:T8334产 地:中国大陆
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T76283b-Hydroxy-5-cholenoic acidInhibitor,3b Hydroxy 5 cholenoic acid,Endogenous Metabolite,inhibit,3bHyd
3b-Hydroxy-5-cholenoic acid is a monohydroxy bile acid of endogenous origin
价 格:¥电议型 号:T7628产 地:中国大陆
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T9165AZD5305repair,AZD5305,Inhibitor,poly ADP ribose polymerase,DNA,AZD-5305,PARP,inhibit,pathway,synthet
AZD5305 is a potent, selective and oral active PARP inhibitor.
价 格:¥电议型 号:T9165产 地:中国大陆
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T9168NSC 617145NSC 617145,breaks,NHEJ,helicase,DSB,abnormalities,WRN,DNA/RNA Synthesis,strand,Rad51,chrom
NSC617145 is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependent manner.
价 格:¥电议型 号:T9168产 地:中国大陆
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T8366Mitochonic acid 5MA5,Inhibitor,Mitochonic acid5,Mitochonic acid-5,Mitochondrial Metabolism,Mitochoni
Mitochonic acid 5 is a derivative of the plant hormone indole-3-acetic acid. Mitochonic acid 5 binds mitochondria and ameliorates renal tubular and cardiac myocyte damage.It has been shown to improve survival of fibroblasts from patients with mitochondrial diseases.
价 格:¥电议型 号:T8366产 地:中国大陆
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T7005UlixertinibERK,VRT 752271,Ulixertinib,inhibit,VRT-752271,BVD 523,BVD523,Inhibitor,Extracellular sign
Ulixertinib (BVD-523, VRT752271) is an effective and reversible ERK1/ERK2 inhibitor. The IC50 of Ulixertinib is less than 0.3 nM for ERK2.
价 格:¥电议型 号:T7005产 地:中国大陆
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T7681AZD-5069inhibit,CXCR,Inhibitor,AZD-5069,AZD5069,AZD 5069,CXC chemokine receptors
AZD-5069 is an chemokine receptor 2 antagonist (CXCR2; IC50 = 0.79 nM).
价 格:¥电议型 号:T7681产 地:中国大陆
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T58885-Methoxysalicylic acid5-甲氧基水杨酸;5-MeOSA
5-Methoxysalicylic acid is a natural product, used as a useful matrix in the MALDI MS analysis of oligonucleotides when combined with spermine
价 格:¥电议型 号:T5888产 地:中国大陆