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产品数:86101
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T6793BRD7552promoter,BRD-7552,islets,human,inhibit,epigenetic,ductal,changes,insulin,BRD 7552,BRD7552,pri
BRD7552 is an inducer of transcription factor PDX1, which increases insulin expression. BRD7552 increases PDX1 expression in mouse αTC cells but not βTC cells.
价 格:¥电议型 号:T6793产 地:中国大陆
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TP1263Fz7-21lipid-binding groove,FZD7,Wnt,Fz7 21,Wnt–β-catenin,Fz-7-21,conformation,FZD7 CRD,intestinal or
Fz7-21 is a peptide antagonist of FZD7 . It antagonises WNT3A-induced Wnt-β-catenin signalling in HEK293 expressing FZD7. Fz7-21 impairs Wnt/β-catenin signaling in HEK293 cells stimulated with exogenous WNT3A (IC50=100 nM) or transfected with a construct expressing WNT3A or WNT1. Fz7-21 also blocks WNT3A-mediated stabilization of β-catenin in mouse L cells (IC50=50 nM).
价 格:¥电议型 号:TP1263产 地:中国大陆
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T8875CD73-IN-3Inhibitor,cancer,CD73 IN 3,CD-73-IN-3,CD73IN3,CD73,Immunosuppression,tumor,inhibit
LY-3475070 is a potent and selective CD73 inhibitor with an IC50 of 28 nM, and its use alone or in combination with pembrolizumab is currently being tested in patients with advanced cancer.
价 格:¥电议型 号:T8875产 地:中国大陆
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T8767PfDHODH-IN-2malaria,Dihydroorotate Dehydrogenase,inhibit,PfDHODH,3D7,Inhibitor,Plasmodium falciparum
PfDHODH-IN-2 is a dihydrothiophenone derivative, is a potent Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH, IC50 : 1.11 μM) inhibitor . It is used an antimalarial agent and can be used for the research of malaria
价 格:¥电议型 号:T8767产 地:中国大陆
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T9094JMJD7-IN-1Inhibitor,Histone Demethylase,cancer,JMJD7,JMJD7 IN 1,inhibit,JMJD7IN1,JMJD-7-IN-1
JMJD7-IN-1 is a potent JMJD7 inhibitor, with an IC50 of 6.62 μM. JMJD7-IN-1 shows good inhibitory activity against cells expressing a high level of JMJD7.
价 格:¥电议型 号:T9094产 地:中国大陆
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T8546BD750Immunosuppressant,JAK,BD750,cell,Janus kinase,BD-750,inhibit,STAT,Inhibitor,BD 750
BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 of 1.5 μM and 1.1 μM in mouse and human T cells, respectively)
价 格:¥电议型 号:T8546产 地:中国大陆
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T7122AZD-7648DNA-dependent protein kinase,inhibit,Apoptosis,AZD7648,A549,OAW42,PI3K,Inhibitor,Phosphoinos
AZD-7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK) with the IC50 of 0.63 nM in an enzyme assay,has anti-tumor activity.
价 格:¥电议型 号:T7122产 地:中国大陆
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TQ0038BrensocatibDipeptidyl Peptidase,DPP,AZD 7986,inhibit,INS-1007,AZD-7986,Brensocatib,INS1007,Inhibitor
AZD7986 is a Dipeptidyl peptidase 1 (DPP1) inhibitor (pIC50s: 6.85, 7.7, 7.6, 7.8, and 7.8 in human, rat, mouse, rabbit, and dog, respectively).
价 格:¥电议型 号:TQ0038产 地:中国大陆
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TQ0225VelsecoratAZD 7594,Inhibitor,AZD-7594,Velsecorat,Glucocorticoid Receptor,AZ-13189620,AZ 13189620,inh
AZD7594 is an effective and selective nonsteroidal glucocorticoid receptor modulator (IC50: 0.9 nM).
价 格:¥电议型 号:TQ0225产 地:中国大陆
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T39341FCPR03antidepressant-like,FCPR-03,PDE4B1,FCPR 03,PDE4D7,PDE4,neuroprotective,ischemic,FCPR03,AKT,GSK
FCPR03 is a selective inhibitor of phosphodiesterase 4 (PDE4) with IC50s of 31 nM, 47 nM, and 60 nM for PDE4B1, PDE4D7, and PDE4 catalytic domain, respectively. FCPR03 has neuroprotective, anti-inflammatory, and antidepressant-like effects.
价 格:¥电议型 号:T39341产 地:中国大陆
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T7516ZD7288inhibit,ICI D-7288,Hyperpolarization activated cyclic nucleotide gated channels,ICI D 7288,ZD
ZD7288, a selective hyperpolarization-activated cyclic nucleotide-gated channel blocker, inhibits hippocampal synaptic plasticity.
价 格:¥电议型 号:T7516产 地:中国大陆
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T8688(Rac)-X77SARS-CoV,(Rac)-X77,protease,SARS coronavirus,inhibit,Inhibitor,(Rac) X77,(Rac)-X-77,coronav
CPD77 is a potent SARS- CoV- 2 main protease inhibitor.
价 格:¥电议型 号:T8688产 地:中国大陆
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T6859I-BRD9cancer,inhibit,Epigenetic Reader Domain,bromodomain-containing protein 7(BRD7),bromodomain and
I-BRD9 is the first selective cellular inhibitor for BRD9 with pIC50 of 7.3.
价 格:¥电议型 号:T6859产 地:中国大陆
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T6421BRD73954Inhibitor,BRD73954,Ac-Tubulin,inhibit,α-tubulin acetylation,HeLa cells,BRD-73954,BRD 73954,H
BRD73954, an effective and specific HDAC inhibitor, which is with IC50 of 36 nM and 120 nM for HDAC6 and HDAC8, respectively.
价 格:¥电议型 号:T6421产 地:中国大陆
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T7699AZD7325modulator,effect,inhibit,Cytochrome P450,Dravet,syndrome,Inhibitor,γ-Aminobutyric acid Recept
AZD-7325 is a GABA-Aα2,3 -selective receptor modulator.
价 格:¥电议型 号:T7699产 地:中国大陆
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T98977-Methoxy-1-naphthaleneacetic acid7Methoxy1naphthaleneacetic acid,7 Methoxy 1 naphthaleneacetic acid
7-Methoxy-1-naphthaleneacetic acid is an inhibitor of auxin action in plants. 7-Methoxy-1-naphthaleneacetic acid inhibits polar auxin transport and tropic responses associated with asymmetric auxin distribution in Arabidopsis and maize. 7-Methoxy-1-naphthaleneacetic acid inhibits auxin transport mediated by AUX1, PIN, and ABCB proteins expressed in yeast.
价 格:¥电议型 号:T9897产 地:中国大陆
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T6093AZD-7762AZD7762
AZD7762, an effective and specific inhibitor of Chk1(IC50=5 nM), is equally potent against Chk2 and less potent against CAM, Yes, Fyn, Lyn, Hck and Lck.
价 格:¥电议型 号:T6093产 地:中国大陆
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T2458CID755673
CID755673 is an effective and specific cell-active inhibitor for PKD (IC50: 182 nM); exhibits selective PKD1 inhibition when compared with PLK1, AKT, CAMKIIα, CAK, and PKC isoforms.
价 格:¥电议型 号:T2458产 地:中国大陆
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T2353BRD7116BRD7716
BRD7116 competitively binds to bacterial DNA gyrase, with cell-non-autonomous anti-leukemia activity.
价 格:¥电议型 号:T2353产 地:中国大陆