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T12040MilademetanMilademetan,DS-3032,
Milademetan is a specific and oral inhibitor of MDM2.
价 格:¥电议型 号:T12040产 地:美洲
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T28038Milademetan HCl (1398568-47-2 free base);化合物 T28038Milademetan HCl|||DS3032|||DS 3032|||DS-3032|||DS
Milademetan is a potent and selective MDM2 inhibitor. MDM2 inhibitor DS-3032b binds to and prevents the binding of MDM2 protein to the transcriptional activation domain of the tumor suppressor protein p53 upon oral administration. By preventing this MDM2-p53 interaction, the proteosome-mediated enzymatic degradation of p53 is inhibited and the transcriptional activity of p53 is restored. This results in the restoration of p53 signaling and leads to the p53-mediated induction of tumor cell apopto
价 格:¥电议型 号:T28038产 地:中国大陆
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T24466Milademetan free base;化合物 T24466DS3032B|||DS-3032|||DS3032|||DS 3032|||DS 3032B|||DS-3032B;DS3032B||
Milademetan (DS-3032b or DS-3032) is a potent and selective MDM2 inhibitor with potential antineoplastic activity. Milademetan (p.o.) binds to and prevents the binding of MDM2 protein to the transcriptional activation domain of the tumor suppressor protein p53.
价 格:¥电议型 号:T24466产 地:中国大陆
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T12040Milademetan;化合物MilademetanRAIN-32|||DS-3032|||DS3032b;RAIN-32|||DS-3032|||DS3032b
Milademetan (DS-3032) is an orally active and potent MDM2 inhibitor with antitumor activity that induces G1 cell cycle arrest, senescence, and apoptosis.Milademetan is used in the study of acute myeloid leukemia and solid tumors.
价 格:¥电议型 号:T12040产 地:中国大陆