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T9041AES-350Histone deacetylases,AES 350,MV4-11,AES-350,Apoptosis,acute myeloid leukemia,AML,Inhibitor,in
AES-350 is a potent and orally active HDAC6 inhibitor(IC50 and a Ki of 0.0244 μM and 0.035 μM, respectively). It is also against HDAC-3, -8, and -11 in an enzymatic activity assay with IC50 values of 0.187 μM, 0.245 μM, and >1μM, respectively. AES-350 triggers apoptosis in AML cells through HDAC inhibition and can be used for acute myeloid leukemia (AML) research.
价 格：￥电议型 号：T9041产 地：中国大陆
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T6695TasquinimodTasquinimod,ABR215050,Inhibitor,ABR 215050,inhibit,Histone deacetylases,HDAC
Tasquinimod is a quinoline-3-carboxamide linomide analog with antiangiogenic and potential antineoplastic activities. Tasquinimod has been shown to decrease blood vessel density but the exact mechanism of action is not known. This agent has also been shown to augment the antineoplastic effects of docetaxel and androgen ablation in a murine model of prostate cancer involving human prostate cancer xenografts.
价 格：￥电议型 号：T6695产 地：中国大陆
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TN1911MareinGLUT1,HDAC,Inhibitor,Akt,inhibit,antioxidative,Marein,Histone deacetylases,antihypertensive,AM
Marein shows neuroprotective effect on PC12 cell damage induced by methylglyoxal, which is due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway, it may be a potent compound for preventing/counteracting diabetic encephalopathy.
价 格：￥电议型 号：TN1911产 地：中国大陆
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T7385WT-161Histone deacetylases,WT161,Inhibitor,inhibit,Apoptosis,WT-161,WT 161,HDAC
WT161 is a potent and selective inhibitor of HDAC6 (IC50:0.40 nM).
价 格：￥电议型 号：T7385产 地：中国大陆
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T8517BelinostatHistone deacetylases,PX-105684,PX 105684,Inhibitor,HDAC,Belinostat,PXD 101,inhibit,Autopha
Belinostat is an inhibitor of hydroxamic acid-type histone deacetylase (HDAC, IC50 of 27 nM in HeLa cell extracts),and with antineoplastic activity.
价 格：￥电议型 号：T8517产 地：中国大陆
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T8280Deacetylasperulosidic Acidinhibit,Inhibitor,Deacetylasperulosidic Acid,Interleukin Related
Deacetylasperulosidic acid is a natural compound of Morinda citrifolia fruit. It has antioxidant activity by increasing superoxide dismutase activity. It also prevents 4-nitroquinoline 1-oxide (4NQO) induced DNA damage in vitro, suppresses IL-2 production along with the activation of natural killer cells.
价 格：￥电议型 号：T8280产 地：中国大陆
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T6481DroxinostatHDAC3,hepatocellular carcinoma (HCC),Droxinostat,NS-41080,Apoptosis,Histone deacetylases,
Droxinostat is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47 μM and 1.46 μM, greater than 8-fold selective against HDAC3 and no inhibition to HDAC1, 2, 4, 5, 7, 9, and 10.
价 格：￥电议型 号：T6481产 地：中国大陆
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T6639RG2833RGFP-109,RG2833,Inhibitor,RG 2833,RGFP 109,RG-2833,HDAC,inhibit,Histone deacetylases
RG2833 (RGFP109), a brain-penetrant HDAC inhibitor, is with IC50 of 60 nM and 50 nM for HDAC1 and HDAC3, respectively.
价 格：￥电议型 号：T6639产 地：中国大陆
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T8480Tenovin-6 Hydrochlorideacetylation,Dihydroorotate Dehydrogenase,protein-deacetylating,Tenovin 6 Hydr
Tenovin-6 Hydrochloride is an SIRT1, SIRT2 and HDAC8 inhibitor(IC50s of 21 μM, 10 μM, and 67 μM for SirT1, SirT2, and SirT3, respectively), and is also a potent p53 activator .
价 格：￥电议型 号：T8480产 地：中国大陆
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T8508HDAC-IN-3Histone deacetylases,Inhibitor,inhibit,HDAC,HDACIN3,HDAC IN 3
HDAC-IN-3 is a potent histone deacetylase (HDAC) inhibitor, and treatment chronic inflammatory disorders.
价 格：￥电议型 号：T8508产 地：中国大陆
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TQ0207SulforaphaneInhibitor,Keap1-Nrf2,Apoptosis,Sulforaphane,Histone deacetylases,inhibit,HDAC
Sulforaphane is derived from the consumption of cruciferous vegetables, such as broccoli. It has shown anticancer and cardioprotective activities.
价 格：￥电议型 号：TQ0207产 地：中国大陆
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T9148KA2507modulatory,KA 2507,KA-2507,colorectal,Histone deacetylases,immune,cancer,antitumor,KA2507,Inhi
KA2507 is a potent and selective HDAC6 inibitor with an IC50 of 2.5nM.
价 格：￥电议型 号：T9148产 地：中国大陆
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T2454DacinostatLAQ-824,Dacinostat,Histone deacetylases,inhibit,Autophagy,HDAC,Inhibitor,LAQ 824
LAQ824 (Dacinostat) is a novel HDAC inhibitor with IC50 of 32 nM and is an activator of the p21 promoter.
价 格：￥电议型 号：T2454产 地：中国大陆
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TN3820Demethoxydeacetoxypseudolaric acid Binhibit,Demethoxydeacetoxypseudolaric acid B,Inhibitor,Deacetyld
Demethoxydeacetoxypseudolaric acid B´s the metabolic reaction of TDA in vivo is mainly occurred in blood and contributes to be the hydrolysis of plasma esterase to ester bond, as well as the glucosylation reaction.
价 格：￥电议型 号：TN3820产 地：中国大陆
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T6713Ulipristalemergency,Deacetyl CDB2914,inhibit,contraception,CDB 3236,Progesterone Receptor,CDB3236,De
Ulipristal is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure.
价 格：￥电议型 号：T6713产 地：中国大陆
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TN32738-Deacetylyunaconitine8Deacetylyunaconitine,8 Deacetylyunaconitine
8-Deacetylyunaconitine is a a diterpenoid alkaloid derived from Aconitum Vilmorinian Radix.
价 格：￥电议型 号：TN3273产 地：中国大陆
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T7064Valproic AcidHistone deacetylases,Mitochondrial Autophagy,bipolar disorder,epilepsy,Autophagy,Apopto
Valproic Acid is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels. Currently, the various molecular mechanisms of action of Valproic Acid have not been completely elucidated. Valproic Acid has been reported to be a potent inhibitor of histone deacetylases (HDACs) in vitro. Valproic Acid is also noted to relieve HDAC-dependent transcriptional repression and causes the hyperacetylation of histones in cultured cells. Additionally,
价 格：￥电议型 号：T7064产 地：中国大陆
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T2430HPOBHDAC,Apoptosis,cells,anticancer,Histone deacetylases,HPOB,tumor,A549,U87,Inhibitor,inhibit,LNCaP
HPOB is an effective and specific HDAC6 inhibitor (IC50: 56 nM), >30-fold selectivity over other HDACs.
价 格：￥电议型 号：T2430产 地：中国大陆
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T6678SplitomicinInhibitor,Histone deacetylases,Splitomycin,HDAC,inhibit,Splitomicin
Splitomicin (IC50 of 60 μM), a specific inhibitor of NAD(+)-dependent histone deacetylase Sir2p, displays a high activity in a cell-based assay.
价 格：￥电议型 号：T6678产 地：中国大陆
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TQ0074ACY-775ACY-775,Histone deacetylases,inhibit,Inhibitor,ACY 775,HDAC,ACY775
ACY-775 is an effective and specific inhibitor of HDAC6 (IC50: 7.5 nM).
价 格：￥电议型 号：TQ0074产 地：中国大陆
