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T9041AES-350Histone deacetylases,AES 350,MV4-11,AES-350,Apoptosis,acute myeloid leukemia,AML,Inhibitor,in
AES-350 is a potent and orally active HDAC6 inhibitor(IC50 and a Ki of 0.0244 μM and 0.035 μM, respectively). It is also against HDAC-3, -8, and -11 in an enzymatic activity assay with IC50 values of 0.187 μM, 0.245 μM, and >1μM, respectively. AES-350 triggers apoptosis in AML cells through HDAC inhibition and can be used for acute myeloid leukemia (AML) research.
价 格：￥电议型 号：T9041产 地：中国大陆
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T6695TasquinimodTasquinimod,ABR215050,Inhibitor,ABR 215050,inhibit,Histone deacetylases,HDAC
Tasquinimod is a quinoline-3-carboxamide linomide analog with antiangiogenic and potential antineoplastic activities. Tasquinimod has been shown to decrease blood vessel density but the exact mechanism of action is not known. This agent has also been shown to augment the antineoplastic effects of docetaxel and androgen ablation in a murine model of prostate cancer involving human prostate cancer xenografts.
价 格：￥电议型 号：T6695产 地：中国大陆
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TN1911MareinGLUT1,HDAC,Inhibitor,Akt,inhibit,antioxidative,Marein,Histone deacetylases,antihypertensive,AM
Marein shows neuroprotective effect on PC12 cell damage induced by methylglyoxal, which is due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway, it may be a potent compound for preventing/counteracting diabetic encephalopathy.
价 格：￥电议型 号：TN1911产 地：中国大陆
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T7385WT-161Histone deacetylases,WT161,Inhibitor,inhibit,Apoptosis,WT-161,WT 161,HDAC
WT161 is a potent and selective inhibitor of HDAC6 (IC50:0.40 nM).
价 格：￥电议型 号：T7385产 地：中国大陆
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T8517BelinostatHistone deacetylases,PX-105684,PX 105684,Inhibitor,HDAC,Belinostat,PXD 101,inhibit,Autopha
Belinostat is an inhibitor of hydroxamic acid-type histone deacetylase (HDAC, IC50 of 27 nM in HeLa cell extracts),and with antineoplastic activity.
价 格：￥电议型 号：T8517产 地：中国大陆
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T6481DroxinostatHDAC3,hepatocellular carcinoma (HCC),Droxinostat,NS-41080,Apoptosis,Histone deacetylases,
Droxinostat is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47 μM and 1.46 μM, greater than 8-fold selective against HDAC3 and no inhibition to HDAC1, 2, 4, 5, 7, 9, and 10.
价 格：￥电议型 号：T6481产 地：中国大陆
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T6639RG2833RGFP-109,RG2833,Inhibitor,RG 2833,RGFP 109,RG-2833,HDAC,inhibit,Histone deacetylases
RG2833 (RGFP109), a brain-penetrant HDAC inhibitor, is with IC50 of 60 nM and 50 nM for HDAC1 and HDAC3, respectively.
价 格：￥电议型 号：T6639产 地：中国大陆
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T8508HDAC-IN-3Histone deacetylases,Inhibitor,inhibit,HDAC,HDACIN3,HDAC IN 3
HDAC-IN-3 is a potent histone deacetylase (HDAC) inhibitor, and treatment chronic inflammatory disorders.
价 格：￥电议型 号：T8508产 地：中国大陆
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TQ0207SulforaphaneInhibitor,Keap1-Nrf2,Apoptosis,Sulforaphane,Histone deacetylases,inhibit,HDAC
Sulforaphane is derived from the consumption of cruciferous vegetables, such as broccoli. It has shown anticancer and cardioprotective activities.
价 格：￥电议型 号：TQ0207产 地：中国大陆
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T9148KA2507modulatory,KA 2507,KA-2507,colorectal,Histone deacetylases,immune,cancer,antitumor,KA2507,Inhi
KA2507 is a potent and selective HDAC6 inibitor with an IC50 of 2.5nM.
价 格：￥电议型 号：T9148产 地：中国大陆
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T2454DacinostatLAQ-824,Dacinostat,Histone deacetylases,inhibit,Autophagy,HDAC,Inhibitor,LAQ 824
LAQ824 (Dacinostat) is a novel HDAC inhibitor with IC50 of 32 nM and is an activator of the p21 promoter.
价 格：￥电议型 号：T2454产 地：中国大陆
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T7064Valproic AcidHistone deacetylases,Mitochondrial Autophagy,bipolar disorder,epilepsy,Autophagy,Apopto
Valproic Acid is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels. Currently, the various molecular mechanisms of action of Valproic Acid have not been completely elucidated. Valproic Acid has been reported to be a potent inhibitor of histone deacetylases (HDACs) in vitro. Valproic Acid is also noted to relieve HDAC-dependent transcriptional repression and causes the hyperacetylation of histones in cultured cells. Additionally,
价 格：￥电议型 号：T7064产 地：中国大陆
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T2430HPOBHDAC,Apoptosis,cells,anticancer,Histone deacetylases,HPOB,tumor,A549,U87,Inhibitor,inhibit,LNCaP
HPOB is an effective and specific HDAC6 inhibitor (IC50: 56 nM), >30-fold selectivity over other HDACs.
价 格：￥电议型 号：T2430产 地：中国大陆
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T6678SplitomicinInhibitor,Histone deacetylases,Splitomycin,HDAC,inhibit,Splitomicin
Splitomicin (IC50 of 60 μM), a specific inhibitor of NAD(+)-dependent histone deacetylase Sir2p, displays a high activity in a cell-based assay.
价 格：￥电议型 号：T6678产 地：中国大陆
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TQ0074ACY-775ACY-775,Histone deacetylases,inhibit,Inhibitor,ACY 775,HDAC,ACY775
ACY-775 is an effective and specific inhibitor of HDAC6 (IC50: 7.5 nM).
价 格：￥电议型 号：TQ0074产 地：中国大陆
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T9745ElevenostatHistone deacetylases,Elevenostat,JB3-22,multiple myeloma,inhibit,HDAC11,Inhibitor,HDAC
Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235??M.
价 格：￥电议型 号：T9745产 地：中国大陆
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T7082HDAC8-IN-1HDAC-8-IN-1,HDAC8IN1,Histone deacetylases,Inhibitor,inhibit,HDAC,HDAC8 IN 1
MDK-7933 (HDAC8-IN-1) is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines. MDK-7933 shows antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5). HDAC8-IN-1 exhibits cytotoxicity against human lung CL1-5 cells without significant cytotoxicity for normal IMR-90 cells[1].
价 格：￥电议型 号：T7082产 地：中国大陆
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T6474Divalproex SodiumMitophagy,Notch,Apoptosis,Histone deacetylases,Autophagy,hepatic fat accumulation,H
Divalproex Sodium binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by increasing brain concentration of GABA and by inhibiting enzymes that catabolize GABA or block the reuptake of GABA into glia and nerve endings. It also is an HDAC inhibitor. Divalproex Sodium is a stable coordination compound comprised of sodium valproate and valproic acid with anticonvulsant and antiepileptic activities. Divalproex may also work by suppressing r
价 格：￥电议型 号：T6474产 地：中国大陆
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T3206NKL 22PAOA；Histone Deacetylase Inhibitor IV
An effective Histone Deacetylase Inhibitor.
价 格：￥电议型 号：T3206产 地：中国大陆
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T3193Pimelic diphenylamide 106TC-H 106；RGFA-8；Histone Deacetylase Inhibitor VII
Pimelic diphenylamide 106 is a slow, tight-binding inhibitor of class I HDAC (with IC50 values of 150 nM , 760 nM and 370 nM for HDAC 1, 2, and 3, respectively), showing no activity against class II HDACs.
价 格：￥电议型 号：T3193产 地：中国大陆
