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T9849HQ461cyclin K degrader,Cyclin dependent kinase,molecular glue,HQ461,HQ 461,HQ-461,CDK12 substrate ph
HQ461 is a molecular glue that promotes CDK12-DDB1 interaction to trigger cyclin K degradation, resulting in decreased CDK12 substrate phosphorylation, downregulation of DNA damage response genes, and cell death.
价 格：￥电议型 号：T9849产 地：中国大陆
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T9758dCeMM3?degradation,dCeMM 3,dCeMM3?,Inhibitor,inhibit,CDK,CDK12,Cyclin dependent kinase,glue degrader
dCeMM3 is a glue degrader. dCeMM3 prompts an interaction of CDK12-cyclin K with a CRL4B ligase complex, result in inducing ubiquitination and degradation of cyclin K.
价 格：￥电议型 号：T9758产 地：中国大陆
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T9370dCBP-1Inhibitor,p300,multiple,CRBN,myeloma,cell,degrader,PROTACs,MYC,CBP,inhibit,dCBP 1,dCBP1,hetero
dCBP-1 is a chemical degrader of p300/CBP. dCBP-1 hijacks the E3 ubiquitin ligase CRBN for selective degradation of p300/CBP. Degradation of p300/CBP by dCBP-1 leads to effective multiple myeloma cell killing.
价 格：￥电议型 号：T9370产 地：中国大陆
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T9117BSJ-4-116CDK,degrader,antiproliferative,inhibit,Kelly,C1039F,BSJ 4 116,Cyclin dependent kinase,PROTA
BSJ-4-116 is a highly potent and selective CDK12 degrader (PROTAC) with an IC50 of 6 nM. It downregulates DDR genes through a premature termination of transcription, primarily through increasing poly(adenylation).
价 格：￥电议型 号：T9117产 地：中国大陆
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T9236WSB1 Degrader 1E3 ligating enzyme,oral,inhibit,anticancer,Ubiquitin conjugating enzyme,Ubiquitin act
WSB1 Degrader 1 is a poten and orally active WD repeat and SOCS box-containing 1 degrader. WSB1 Degrader 1 has anticancer metastatic effects
价 格：￥电议型 号：T9236产 地：中国大陆
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T4207(S,R,S)-AHPC hydrochlorideVHL Ligand 1 hydrochloride；Protein degrader 1 hydrochloride；ULM-1
Protein degrader 1 hydrochloride is a building block in the synthesis of proteolysis-targeting chimera technologies (PROTACs).
价 格：￥电议型 号：T4207产 地：中国大陆
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T13722Homo-PROTAC pVHL30 degrader 1
Homo-PROTAC pVHL30 degrader 1 is a potent pVHL30 degrader based on PROTAC.
价 格：￥电议型 号：T13722产 地：中国大陆
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T13721Homo-PROTAC cereblon degrader 1
Homo-PROTAC cereblon degrader 1 is a highly potent and efficient cereblon (CRBN) degrader with only minimal effects on IKZF1 and IKZF3.
价 格：￥电议型 号：T13721产 地：中国大陆
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T10485PROTAC Bcl2 degrader-1PROTAC Bcl2 degrader-1
PROTAC Bcl2 degrader-1 is a PROTAC, which potently and selectively induces the degradation of Mcl-1 (IC50: 11.81 μM) and Bcl-2 (IC50: 4.94 μM; DC50: 3.0 μM).
价 格：￥电议型 号：T10485产 地：美洲
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T11975PROTAC Mcl1 degrader-1PROTAC Mcl1 degrader-1
PROTAC Mcl1 degrader-1 induces the ubiquitination and proteasomal degradation of Mcl-1 by introducing the E3 ligase cereblon (CRBN)-binding ligand pomalidomide to Mcl-1 inhibitor S1-6 with μM-range affinity.?PROTAC Mcl1 degrader-1, a proteolysis targeting
价 格：￥电议型 号：T11975产 地：美洲
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T12556PROTAC B-Raf degrader 1PROTAC B-Raf degrader 1
PROTAC B-Raf degrader 1 is a proteolysis targeting chimera (PROTAC) for the degradation of B-Raf,PROTAC B-Raf degrader 1 With anti-cancer activity.
价 格：￥电议型 号：T12556产 地：美洲
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T12559PROTAC BET degrader-2PROTAC BET degrader-2
PROTAC BET degrader-2 is a highly potent degrader of Bromodomain and Extra-Terminal (BET) proteins (IC50 of 9.6 nM ).
价 格：￥电议型 号：T12559产 地：美洲
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T12560PROTAC BRD9 Degrader-1PROTAC BRD9 Degrader-1
PROTAC BRD9 Degrader-1 is a lead PROTAC BRD9 chemical degrader with IC50 of 13.5 nM.
价 格：￥电议型 号：T12560产 地：美洲
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T13721Homo-PROTAC cereblon degrader 1Homo-PROTAC cereblon degrader 1
Homo-PROTAC cereblon degrader 1 ?is a highly potent and efficient cereblon (CRBN) degrader with only minimal effects on IKZF1 and IKZF3.
价 格：￥电议型 号：T13721产 地：美洲
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T13722Homo-PROTAC pVHL30 degrader 1Homo-PROTAC pVHL30 degrader 1
Homo-PROTAC pVHL30 degrader 1 is a potent pVHL30 degrader based on PROTAC.
价 格：￥电议型 号：T13722产 地：美洲
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T13840PROTAC FAK degrader 1PROTAC FAK degrader 1
PROTAC FAK degrader 1 is a selective and potent degrader of focal adhesion kinase (Fak) (IC50 of 6.5 nM).
价 格：￥电议型 号：T13840产 地：美洲
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T13844PROTAC K-Ras Degrader-1PROTAC K-Ras Degrader-1
PROTAC K-Ras Degrader-1 is potent degrader of K-Ras based PROTAC.
价 格：￥电议型 号：T13844产 地：美洲
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T13847PROTAC SGK3 degrader-1PROTAC SGK3 degrader-1,SGK3-PROTAC1,
PROTAC SGK3 degrader-1, is a potent SKG3 degrader based on PROTAC.
价 格：￥电议型 号：T13847产 地：美洲
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T13849PROTAC BET Degrader-1PROTAC BET Degrader-1
PROTAC BET Degrader-1 is a potent degrader of BET based on PROTAC.
价 格：￥电议型 号：T13849产 地：美洲
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T8745PROTAC BRAF-V600E degrader-1；化合物2417296-84-3Compound 23；Compound 23
PROTAC BRAF-V600E degrader-1 (Compound 23) selectively induces degradation of BRAF-V600E but not wildtype BRAF.
价 格：￥电议型 号：T8745产 地：中国大陆
