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T8409SYN1143c-Met/HGFR,SYN-1143,tumor,RON,dual,inhibit,SYN1143,SYN 1143,cancer,Inhibitor,c-Met
AMG-1 is a potent inhibitor of human RON and c-Met.In vitro kinase assays showed that compound I is a potent inhibitor of human RON and c-Met with IC50s of 9 and 4 nmol/L, respectively.
价 格:¥电议型 号:T8409产 地:中国大陆
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T63536Dual FAAH/sEH-IN-1
Dual FAAH/sEH-IN-1 is a dual inhibitor of sEH (soluble epoxide hydrolase) (IC50: 9.6 nM) and FAAH (fatty acid amide hydrolase) (IC50: 7 nM) with high affinity and anti-inflammatory activity.
价 格:¥电议型 号:T63536产 地:中国大陆
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T40187GNF2133β-cell,RIP-DTA mice,Inhibitor,insulin secretion,GNF2133,inhibit,Dual specificity tyrosine reg
GNF2133 is an effective and selective inhibitor of DYRK1A with IC50s of 6.2 nM. GNF2133 can be used in studies about type 1 diabetes.
价 格:¥电议型 号:T40187产 地:中国大陆
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T7323BCI-215specificity,Phosphatase,DUSP-MKP,inhibit,Inhibitor,MAPK,BCI-215,BCI215,BCI 215,dual
BCI-215 causes selective cancer cell cytotoxicity in part through non-redox-mediated activation of MAPK signaling
价 格:¥电议型 号:T7323产 地:中国大陆
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T14980CLK-IN-T3CDC-like,Dual specificity tyrosine phosphorylation regulated kinase,inhibit,Dual specificit
CLK-IN-T3 is an inhibitor of CLK1, CLK2, and CLK3 with IC50s of 0.67, 15, and 110 nM. CLK-IN-T3 exhibits anti-cancer activity.
价 格:¥电议型 号:T14980产 地:中国大陆
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TQ0111LDN-192960DYRK,Dual specificity tyrosine regulated kinase,Inhibitor,Dual specificity tyrosine phosph
LDN-192960 is a potent inhibitor of Haspin and DYRK2 (IC50s: 10 nM and 48 nM).
价 格:¥电议型 号:TQ0111产 地:中国大陆
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T5093Pim1/AKK1-IN-1LKB1/AAK1 dual inhibitor;MDK-2275
Pim1/AKK1-IN-1 is a potent multi-kinase inhibitor with Kd values of 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1 respectively, and also inhibits MPSK1 and TNIK.
价 格:¥电议型 号:T5093产 地:中国大陆
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T2381AbemaciclibLY2835219;CDK4/6 dual inhibitor
LY2835219 is an effective and specific CDK4/6 inhibitor (IC50: 2/10 nM).
价 格:¥电议型 号:T2381产 地:中国大陆
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T1811WH-4-023KIN001-112;Dual LCK/SRC inhibitor;KIN112
WH-4-023 is a potent and orally active Lck/Src inhibitor. It also potently inhibits SIK.
价 格:¥电议型 号:T1811产 地:中国大陆
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T1811WH-4-023WH-4-023,Dual LCK/SRC inhibitor,KIN001-112
WH-4-023 is a potent and orally active Lck/Src inhibitor. It also potently inhibits SIK.
价 格:¥电议型 号:T1811产 地:美洲
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T2381AbemaciclibAbemaciclib,LY2835219,CDK4/6 dual inhibitor
LY2835219 is an effective and specific CDK4/6 inhibitor (IC50: 2/10 nM).
价 格:¥电议型 号:T2381产 地:美洲
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T5093Pim1/AKK1-IN-1Pim1/AKK1-IN-1,LKB1/AAK1 dual inhibitor,MDK-2275
Pim1/AKK1-IN-1 is a potent multi-kinase inhibitor with Kd values of 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1 respectively, and also inhibits MPSK1 and TNIK.
价 格:¥电议型 号:T5093产 地:美洲
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T82524Dual photoCORM 1;化合物 Dual photoCORM 1Dual photoCORM 1
Dual photoCORM 1 (compound 5), a metal-free, photoactive, dual carbon monoxide releasing molecule (CORM), demonstrates efficient cellular uptake and enables real-time tracking of CO release via a colorimetric change in B16F10 cancer cells [1].
价 格:¥电议型 号:T82524产 地:中国大陆
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T75150GIP/GLP-1 dual receptor agonist-1;化合物 GIP/GLP-1 dual receptor agonist-1GIP/GLP-1 dual receptor agoni
GIP/GLP-1 dual receptor agonist-1 (compound 4), a receptor agonist for both GIP and GLP-1, shows potential for the research of metabolic disorders and fatty liver diseases, such as nonalcoholic steatohepatitis (NASH) and nonalcoholic fatty liver disease (NAFLD) [1].
价 格:¥电议型 号:T75150产 地:中国大陆
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T74991Dual AChE-MAO B-IN-3;化合物 Dual AChE-MAO B-IN-3Dual AChE-MAO B-IN-3
Dual AChE-MAO B-IN-3 (Compound C10) is a potent inhibitor of both AChE and MAO-B, exhibiting IC50 values of 0.58 μM and 0.41 μM, respectively. This dual-binding inhibitor targets the catalytic anionic site and peripheral anionic site of AChE, making it relevant for Alzheimer’s disease (AD) research [1].
价 格:¥电议型 号:T74991产 地:中国大陆
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T63536Dual FAAH/sEH-IN-1;化合物Dual FAAH/sEH-IN-1Dual FAAH/sEH-IN-1
Dual FAAH/sEH-IN-1 is a dual inhibitor of sEH (soluble epoxide hydrolase) (IC50: 9.6 nM) and FAAH (fatty acid amide hydrolase) (IC50: 7 nM) with high affinity and anti-inflammatory activity.
价 格:¥电议型 号:T63536产 地:中国大陆
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T62172Dual AChE-MAO B-IN-1;化合物 Dual AChE-MAO B-IN-1Dual AChE-MAO B-IN-1
Dual AChE-MAO B-IN-1 (compound 15) is a safe, metabolically stable neuroprotective agent.Dual AChE-MAO B-IN-1 is a potent, orally active CNS-permeable inhibitor of human AChE (IC50=550 nM) and MAO-B (IC50=8.2 nM), and has low in vitro activity against AChE and MAO-B with IC50 values of 550 nM, 8.2 nM respectively.
价 格:¥电议型 号:T62172产 地:中国大陆
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T62152Dual AChE-MAO B-IN-2;化合物 Dual AChE-MAO B-IN-2Dual AChE-MAO B-IN-2
Dual AChE-MAO B-IN-2 is a potent, dual inhibitor of AChE (IC50: 0.12 μM) and MAO B (IC50: 0.01 μM).Dual AChE-MAO B-IN-2 has potential for Alzheimer´s disease studies.
价 格:¥电议型 号:T62152产 地:中国大陆
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T5093Pim1/AKK1-IN-1;化合物Pim1/AKK1-IN-1LKB1/AAK1 dual inhibitor|||MDK-2275;LKB1/AAK1 dual inhibitor|||MDK-2
Pim1/AKK1-IN-1 (LKB1/AAK1 dual inhibitor) is a potent multi-kinase inhibitor with Kd values of 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1 respectively, and also inhibits MPSK1 and TNIK.
价 格:¥电议型 号:T5093产 地:中国大陆
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T2381Abemaciclib;化合物AbemaciclibCDK4/6 dual inhibitor|||LY2835219;CDK4/6 dual inhibitor|||LY2835219
Abemaciclib (LY2835219) is a dual inhibitor of CDK4/6 (IC50=2/10 nM) with selectivity and specificity. Abemaciclib has antitumor activity and is used to treat advanced or metastatic breast cancer.
价 格:¥电议型 号:T2381产 地:中国大陆