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T9240sulfopinneuroblastoma,antiproliferative,PIN1-3,tumors,cancer,pancreatic,Inhibitor,sulfopin,inhibit,c
Sulfopin is a highly selective covalent inhibitor of Pin1 with an apparent Ki of 17nM. Sulfopin blocks Myc-driven tumors in vivo.
价 格:¥电议型 号:T9240产 地:中国大陆
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T9820GPI-1485neurofunctional,regeneration,Inhibitor,ligand,stroke,GPI-1485,GPI 1485,inhibit,immunophilin,
GPI-1485 (GM1485) is a nonimmunosuppressive immunophilin ligand, promoting neurofunctional improvement and neural regeneration following stroke.
价 格:¥电议型 号:T9820产 地:中国大陆
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T9124Laninamivir octanoateH2N2,CS8958,H3N2,inhaled,CS 8958,Laninamivir octanoate,neuraminidase,inhibit,An
Laninamivir octanoate is a long acting influenza neuraminidase (NA) inhibitor which shows superior anti-influenza virus activity.
价 格:¥电议型 号:T9124产 地:中国大陆
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T60080TMPHneurol disorder,nAChR,Nicotinic acetylcholine receptors,neuronal nicotinic receptors,selective i
TMPH is an inhibitor of nAChR and inhibits nAChRs lacking α5, α6, or β3 subunits. TMPH can be used in studies about nAChR dysfunction or neurological disorders.
价 格:¥电议型 号:T60080产 地:中国大陆
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TP2309NEUROTENSIN TFA (39379-15-2 free base)NEUROTENSIN TFA (39379 15 2 free base),NEUROTENSIN TFA (393791
Neurotensin (NT) is an endogenous 13 amino acid neuropeptide with profound opioid-independent analgesic effects. It behaves as a neurotransmitter in the brain, as a hormone in the gut, and also as a neuromodulator. It is implicated in the pathophysiology of several CNS disorders (including schizophrenia, Parkinson´s disease, drug abuse, pain, cancer, inflammation, eating disorders and central control of blood pressure) due to its association with a wide variety of neurotransmitter systems
价 格:¥电议型 号:TP2309产 地:中国大陆
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TP1018LUrechistachykinin II acetateUrechistachykinin II acetate
Urechistachykinin II acetate is an invertebrate rapid kinin-related peptide (TRPs) isolated from carotenoid worms, shows antimicrobial activities without a hemolytic effect
价 格:¥电议型 号:TP1018L产 地:中国大陆
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T4074GSK-872translocation,GSK-872,neurological,HMGB1,Receptor-interacting protein kinases,brain,GSK 872,c
GSK872 (GSK2399872A) is an effective and specific RIP3 kinase inhibitor. It binds RIP3 kinase domain with high affinity (IC50: 1.8 nM) and inhibits kinase activity (IC50: 1.3 nM).
价 格:¥电议型 号:T4074产 地:中国大陆
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T21980PD 198306MAPK,inhibit,neuropathic,Inhibitor,MAP2K,rabies,mitogen-activated protein,drug,MAPKK,PD-198
PD 198306 is a selective inhibitor of MAPK/ERK-kinase (MEK) with antihyperalgesic effects. PD 198306 reduces the Streptozocin-induced increase in the level of active ERK1.
价 格:¥电议型 号:T21980产 地:中国大陆
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T6917OleuropeinPPARγ,olive,PPAR,Peroxisome proliferator-activated receptors,inhibit,Apoptosis,leaves,Oleu
Oleuropein is an antioxidant polyphenol isolated from olive leaf.
价 格:¥电议型 号:T6917产 地:中国大陆
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T8435YM90Kanticonvulsant,AMPA,Inhibitor,ischemia,inhibit,neuroprotective,Ionotropic glutamate receptors,Y
YM90K hydrochloride is an antagonist of AMPA receptor.
价 格:¥电议型 号:T8435产 地:中国大陆
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T8963CYM2503Neuropeptide Y Receptor,electrographic seizure,NPY receptor,CYM 2503,seizure,inhibit,CYM2503,
CYM2503 is a positive allosteric modulator (PAM) of the GAL2 receptor that potentiates galanin-induced IP1 production in vitro. It has no affinity for the orthosteric galanin binding site of the receptor (as measured by its inability to displace iodinated galanin, or to induce IP1 accumulation on its own).
价 格:¥电议型 号:T8963产 地:中国大陆
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TP1059Peptide YY (PYY) (3-36), humanNeuropeptide Y Receptor,Inhibitor,NPY receptor,Peptide YY (PYY) (336),
Peptide YY (PYY) (3-36), human is a gut hormone peptide. Peptide YY (PYY) (3-36), human acts as a Y2 receptor agonist to reduce appetite.
价 格:¥电议型 号:TP1059产 地:中国大陆
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T7549Talnetantschizophrenia,SB223412,NK receptor,Inhibitor,hNK-2,Talnetant,Neurokinin Receptor,Tachykinin
Talnetant is a selective, competitive, brain-penetrant NK3 receptor antagonist with the ability to modulate mesolimbic and mesocortical dopaminergic neurotransmission
价 格:¥电议型 号:T7549产 地:中国大陆
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TN1637EurycomalactoneDNA double-strand,Eurycomalactone,NF-κB,protein synthesis,Inhibitor,Nuclear factor-ka
Eurycomalactone is a natural product isolated from Eurycoma longifolia Jack., acts as a potent NF-κB inhibitor( IC50 of 0.5 μM). Eurycomalactone inhibits protein synthesis, depletes cyclin D1, but does not affect TNFα-induced degradation of IκBα or the phosphorylation of IKKα/β and IκBα.
价 格:¥电议型 号:TN1637产 地:中国大陆
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T8505SC-236SC-236,gastric,PPAR,cancer,ischemia,Liver,inhibit,allodynia,Inhibitor,fibrogenesis,neuroprotec
Sc 236 is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).
价 格:¥电议型 号:T8505产 地:中国大陆
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TP1380Galanin (1-16), mouse, porcine, ratGalanin (1-16), mouse, porcine, rat,Neuropeptide Y Receptor,Inhib
Galanin (1-16), mouse, porcine, rat is a hippocampal galanin receptor agonist(Kd = 3 nM) with high biological activity on locus coeruleus neurons.
价 格:¥电议型 号:TP1380产 地:中国大陆
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T6822Hydroxy-Dynasoreinhibit,Hydroxy-Dynasore,vesicle,Dynamin,Hydroxy Dynasore,Neuron,clathrin‐coated,Inh
Dyngo-4a , a effective dynamin inhibitor, inhibits withDynI (brain), DynI (rec), and DynII (rec) of IC50 of 0.38 μM, 1.1 μM, and 2.3 μM, respectively.
价 格:¥电议型 号:T6822产 地:中国大陆
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T6S1369Vitexinneurodegeneration,Vitexin,anti-cancer,anti-nociceptive,inhibit,Medicinal,anti-hypertensive,an
1. Vitexin has antinociceptive and antispasmodic activities. 2. Vitexin exhibits a prominent first-pass effect. 3. Vitexin has antioxidant, antimyeloperoxidase, and α-glucosidase inhibitory activities. 4. Vitexin can either inhibit or induce activities of CYP2C11 and CYP3A1. 5. Vitexin induces the novel p53-dependent metastatic and apoptotic pathway. 6. Vitexin protects brain against cerebral I/R injury, and this effect may be regulated by mitogen-activated protein kinase (MAPK) and apoptosis si
价 格:¥电议型 号:T6S1369产 地:中国大陆
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T8849PF-9601Nexcitotoxicity,neurodegenerative diseases,MAO,PF9601N,Monoamine Oxidase,MAO-B inhibitor,neur
PF-9601N showed high potency and selectivity as a MAO-BI (monoamine oxidase type B inhibitor) and also demonstrated remarkable neuroprotective properties in several in vivo and cellular models of PD.
价 格:¥电议型 号:T8849产 地:中国大陆
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T6923Ozanimodneurosurgery,sphingosine 1-phosphate (S1P),LPL Receptor,inhibit,RPC1063,Lysophospholipid Rec
Ozanimod (RPC1063) is a specific oral S1P Receptor 1 modulator. Ozanimod has been used in trials studying the treatment of Crohn´s Disease, Ulcerative Colitis, Multiple Sclerosis, and Relapsing Multiple Sclerosis.
价 格:¥电议型 号:T6923产 地:中国大陆