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T9856FLT3-IN-10
FLT3-IN-10 (compound 7c) is a potent inhibitor of FMS-like tyrosine kinase 3 (FLT3). FLT3-IN-10 shows the potential for the treatment of FLT3-mutated acute myeloid leukemia (AML).
价 格：￥电议型 号：T9856产 地：中国大陆
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T2051SKLB4771FLT3-?IN-?1；FLT3-IN-1
FLT3-IN-1 is a novel potent and selective Flt3 inhibitor.
价 格：￥电议型 号：T2051产 地：中国大陆
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T2051FLT3-IN-1FLT3-IN-1,FLT3-?IN-?1,SKLB4771
FLT3-IN-1 is a novel potent and selective Flt3 inhibitor.
价 格：￥电议型 号：T2051产 地：美洲
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T78176FLT3-IN-19；化合物 FLT3-IN-19FLT3-IN-19
FLT3-IN-19 (Comp 50) is a potent, selective inhibitor of FLT3, demonstrating an IC50 value of 0.213 nM, and is applicable in research pertaining to acute myeloid leukemia (AML) [1].
价 格：￥电议型 号：T78176产 地：中国大陆
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T73142FLT3-IN-18；化合物 FLT3-IN-18FLT3-IN-18
FLT3-IN-18, a potent and selective FLT3 inhibitor, exhibits an IC50 value of 0.003 μM. It effectively induces apoptosis and G1 phase cell cycle arrest, while inhibiting FLT3 and STAT5 phosphorylation. This compound holds potential for acute myeloid leukemia (AML) research.
价 格：￥电议型 号：T73142产 地：中国大陆
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T64104JAK2/FLT3-IN-1 TFA；化合物 JAK2/FLT3-IN-1 TFAJAK2/FLT3-IN-1 TFA
JAK2/FLT3-IN-1 (TFA) is an orally active dual inhibitor of JAK2/FLT3 that exhibits anticancer effects, acting on JAK2 (IC50: 0.7 nM), FLT3 (IC50: 4 nM), JAK1 (IC50: 26 nM) and JAK3 (IC50: 39 nM).
价 格：￥电议型 号：T64104产 地：中国大陆
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T63174FLT3-IN-17；化合物 FLT3-IN-17FLT3-IN-17
FLT3-IN-17 is an FAK inhibitor (IC50: 12 nM). FLT3-IN-17 inhibits the activity of CYPs and FLT3 mutants and has an IC50 of <0.5 nM for D835Y. FLT3-IN-17 can be used in cancer research.
价 格：￥电议型 号：T63174产 地：中国大陆
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T63058FLT3-IN-14；化合物 FLT3-IN-14FLT3-IN-14
FLT3-IN-14 is a potent inhibitor of FLT3, acting on FLT3-WT (IC50: 5.6 nM) and FLT3-ITD (IC50: 1.4 nM). FLT3-IN-14 inhibits FLT3 (Y591) phosphorylation, arrests the cell cycle in G1 phase and induces apoptosis.
价 格：￥电议型 号：T63058产 地：中国大陆
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T62607FLT3-IN-15；化合物 FLT3-IN-15FLT3-IN-15
FLT3-IN-15 is an orally active and potent FLT3 inhibitor, capable of acting on FLT3 (IC50: 0.87 nM) and FLT3/D835Y (IC50: 0.32 nM).
价 格：￥电议型 号：T62607产 地：中国大陆
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T62412FLT3-IN-12；化合物 FLT3-IN-12FLT3-IN-12
FLT3-IN-12 is a selective, potent, orally active FLT3 kinase inhibitor that acts on FLT3-WT (IC50: 1.48 nM) and FLT3-D835Y (IC50: 2.87 nM). FLT3-IN-12 is more selective than c-KIT (>1000-fold). FLT3-IN-12 showed significant anti-AML effects, with an IC50 value of 0.75 nM for MV4-11 cells.
价 格：￥电议型 号：T62412产 地：中国大陆
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T62260FLT3-IN-11；化合物 FLT3-IN-11FLT3-IN-11
FLT3-IN-11 (compound 30) is an orally active, potent and selective inhibitor of FLT3 kinase, acting on wild-type FLT3 (IC50: 7.22 nM) and FLT3-D835Y (IC50: 4.95 nM). FLT3-IN-11 exhibited significant anti-AML effects with an IC50 value of 3.2 nM for MV4-11 cells.
价 格：￥电议型 号：T62260产 地：中国大陆
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T61101FLT3-IN-13；化合物 FLT3-IN-13FLT3-IN-13
FLT3-IN-13 (compound 20) is a highly effective inhibitor targeting both topoisomerase II and FLT3 proteins in leukemic cells. It exhibits potent activity against these targets, with IC50 values of 2.26 μM for both. Moreover, FLT3-IN-13 induces cell cycle arrest at the G2/M phase and promotes apoptosis. Notably, it displays considerable anticytotoxic activity, specifically against leukemia [1].
价 格：￥电议型 号：T61101产 地：中国大陆
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T2051SKLB4771；化合物FLT3-IN-1FLT3-?IN-?1|||FLT3-IN-1；FLT3-?IN-?1|||FLT3-IN-1
SKLB4771 (FLT3-IN-1) is a novel potent and selective Flt3 inhibitor.
价 格：￥电议型 号：T2051产 地：中国大陆
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T11707JAK2/FLT3-IN-1；化合物 T11707JAK2/FLT3-IN-1
JAK2/FLT3-IN-1 has anti-cancer activity. JAK2/FLT3-IN-1 is a potent and orally effective dual JAK2/FLT3 (Janus kinase 2/ FMS-like tyrosine kinase 3) inhibitor with IC50 values of 0.7 nM, 4 nM, 26 nM and 39 nM for JAK2, FLT3, JAK1 and JAK3, respectively.
价 格：￥电议型 号：T11707产 地：中国大陆
