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T9303MRTX1133KRAS,Ras,MRTX 1133,G12D,cells,active,wild-type,phosphorylation,mutant,MRTX1133,inactive,ERK,
MRTX1133 is a potent, selective, and noncovalent inhibitor of KRAS G12D. MRTX1133 exhibits an estimated KD against KRAS G12D of 0.2 pM. MRTX1133 inhibits mutant KRAS-dependent signal transduction by preventing SOS1-catalyzed nucleotide exchange and/or formation of the KRAS G12D/GTP/RAF1 complex. MRTX1133 selectively inhibits KRAS G12D mutant tumor cells with no effect on KRAS wild-type. MRTX1133 exhibits single digit nanomolar activity in cellular assays and marked in vivo efficacy in tumor mode
价 格：￥电议型 号：T9303产 地：中国大陆
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T62228KRAS G12D inhibitor 14
KRAS G12D inhibitor 14 is an effective inhibitor of KRAS G12D, showing significant antitumor effect and tumor growth inhibition in CT26 tumor models.
价 格：￥电议型 号：T62228产 地：中国大陆
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T79072KRAS G12D modulator-1；化合物 KRAS G12D modulator-1KRAS G12D modulator-1
KRAS G12D modulator-1 (compound 6), a potent modulator of KRAS G12D, exhibits IC50 values ranging from 1-10 μM against NEA-G12D, PPI-G12D, and p ERK-AGS, and is utilized in cancer research [1].
价 格：￥电议型 号：T79072产 地：中国大陆
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T78212RMC-9805；化合物 RMC-9805KRAS G12D inhibitor 18|||KRAS G12D IN 18；KRAS G12D inhibitor 18|||KRAS G12D IN
RMC-9805 is a potent KRAS G12D inhibitor with potential anti-tumor and inhibitory activity against tumor cell proliferation for the study of pancreatic cancer.
价 格：￥电议型 号：T78212产 地：中国大陆
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T78170Kras4B G12D-IN-1；Kras4B G12D 抑制剂 1Kras4B G12D-IN-1
Kras4B G12D-IN-1 is an anticancer agent that functions as an inhibitor of the Kras4B G12D protein. It effectively reduces the expression of Kras protein in mouse embryonic fibroblasts (MEFs) harboring the Kras4B G12D mutation[1].
价 格：￥电议型 号：T78170产 地：中国大陆
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T77804KRAS G12D mutation regulator 4；化合物 KRAS G12D mutation regulator 4KRAS G12D mutation regulator 4
KRAS G12D mutation regulator 4 can be used in studies about Ras.
价 格：￥电议型 号：T77804产 地：中国大陆
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T74663KRAS G12D inhibitor 17；化合物 KRAS G12D inhibitor 17KRAS G12D inhibitor 17
KRAS G12D Inhibitor 17 (example 8), a quinazoline-linked (4R)-4-hydroxy-L-prolinamide compound, acts as a proteolysis targeting chimera (PROTAC) [1], specifically inducing degradation of the G12D-mutation KRAS protein.
价 格：￥电议型 号：T74663产 地：中国大陆
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T74607KRAS G12D inhibitor 15；化合物 KRAS G12D inhibitor 15KRAS G12D inhibitor 15
KRAS G12D inhibitor 15 is a potent inhibitor specifically targeting the KRAS G12D mutation. It holds potential for research into numerous diseases or disorders, including cancer and its metastases[1].
价 格：￥电议型 号：T74607产 地：中国大陆
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T73828KRAS G12D inhibitor 3 TFA；化合物 KRAS G12D inhibitor 3 TFAKRAS G12D inhibitor 3 TFA
KRAS G12D Inhibitor 3 TFA, exhibiting an inhibitory concentration (IC50) of less than 500 nM, is effective as an antitumor agent.
价 格：￥电议型 号：T73828产 地：中国大陆
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T72394KRAS G12D inhibitor 3；化合物 KRAS G12D inhibitor 3KRAS G12D inhibitor 3
KRAS G12D Inhibitor 3, a compound targeting the KRAS G12D mutation, demonstrates potent antitumor efficacy with an inhibitory concentration (IC50) of less than 500 nM.
价 格：￥电议型 号：T72394产 地：中国大陆
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T72355KRAS G12D inhibitor 16；化合物 KRAS G12D inhibitor 16KRAS G12D inhibitor 16
KRAS G12D Inhibitor 16 is a potent compound targeting the KRAS G12D and its mutation, exhibiting inhibitory activity with IC50 values of 0.7 nM and 0.35 μM, respectively. It is utilized in researching various malignant tumors including pancreatic ductal adenocarcinomas (PDAC), colon and rectal carcinomas (CRC), and non-small cell lung carcinomas (NSCLC).
价 格：￥电议型 号：T72355产 地：中国大陆
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T72345KRAS G12D inhibitor 10；化合物 KRAS G12D inhibitor 10KRAS G12D inhibitor 10
KRAS G12D Inhibitor 10 is a potent agent targeting the KRAS G12D mutation, a variant in the Ras protein family crucial for cellular growth and development. This compound shows promise for investigating cancers mediated by KRAS G12D.
价 格：￥电议型 号：T72345产 地：中国大陆
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T64178KRAS G12D inhibitor 13；化合物 KRAS G12D inhibitor 13KRAS G12D inhibitor 13
KRAS G12D inhibitor 13 is a potent inhibitor of KRAS G12D. KRAS G12D inhibitor 13 has shown potential for the investigation of KRAS G12D-mediated cancers.
价 格：￥电议型 号：T64178产 地：中国大陆
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T64031KRAS G12D inhibitor 9；化合物 KRAS G12D inhibitor 9KRAS G12D inhibitor 9
KRAS G12D inhibitor 9 is a potent inhibitor of KRAS G12D. Among them, the RAS protein family is an important intracellular signaling molecule that plays an important role in growth and development. KRAS G12D inhibitor 9 shows research potential for KRAS G12D-mediated cancer.
价 格：￥电议型 号：T64031产 地：中国大陆
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T63577KRAS G12D inhibitor 11；化合物 KRAS G12D inhibitor 11KRAS G12D inhibitor 11
KRAS G12D inhibitor 11 is a potent inhibitor of KRAS G12D. The Ras family of proteins are important intracellular signaling molecules that play an important role in growth and development, and KRAS G12D inhibitor 11 has shown potential for the investigation of KRAS G12D-mediated cancers.
价 格：￥电议型 号：T63577产 地：中国大陆
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T63028KRAS G12D inhibitor 12；化合物 KRAS G12D inhibitor 12KRAS G12D inhibitor 12
KRAS G12D inhibitor 12 is an effective inhibitor of KRAS G12D. The Ras protein family is an important intracellular signaling molecule, which plays an important role in growth and development. KRAS G12D inhibitor 12 has the potential to perform KRAS G12D-mediated cancer studies.
价 格：￥电议型 号：T63028产 地：中国大陆
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T62228KRAS G12D inhibitor 14；KRAS G12D抑制剂14KRAS G12D inhibitor 14
KRAS G12D inhibitor 14 is a potent inhibitor of KRAS G12D that binds KRAS G12D protein (Kd: 33 nM). KRAS G12D inhibitor 14 inhibits the active form of KRAS G12D (KRAS G12D-GTP), but not KRAS G13D.
价 格：￥电议型 号：T62228产 地：中国大陆
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T40282KRAS G12D inhibitor 7；KRAS G12D inhibitor 7KRAS G12D inhibitor 7
KRAS G12D inhibitor 7, is a highly potent inhibitor specifically targeting KRAS G12D.
价 格：￥电议型 号：T40282产 地：中国大陆
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T40281KRAS G12D inhibitor 6；KRAS G12D inhibitor 6KRAS G12D inhibitor 6
KRAS G12D inhibitor 6 is an efficacious compound that effectively inhibits KRAS G12D.
价 格：￥电议型 号：T40281产 地：中国大陆
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T40246KRAS G12D inhibitor 5；KRAS G12D inhibitor 5KRAS G12D inhibitor 5
KRAS G12D inhibitor 5 is a KRAS G12D inhibitor for the potential treatment of pancreatic cancer.
价 格：￥电议型 号：T40246产 地：中国大陆
