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T7165Basmisanilα subunit-containing GABAA receptors (GABAAα5),RO-5186582,RG-1662,psychiatric disorders,ne
Basmisanil is a negative allosteric modulator/inverse agonist of GABAAα5 receptors.Formulations containing basmisanil are in clinical trials for the treatment of cognitive impairments associated with Down syndrome.
价 格：￥电议型 号：T7165产 地：中国大陆
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T62885GABAA receptor modulator-2；化合物 GABAA?receptor?modulator-2GABAA receptor modulator-2
GABAA receptor modulator-2 (Compound 20) is a selective, orally active α5-GABAAR negative conformation modulator (Ki: 4.1 nM). gABAA receptor modulator-2 exhibits high metabolic stability and a good central nervous system safety profile.
价 格：￥电议型 号：T62885产 地：中国大陆
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T62426GABAA receptor agent 2 TFA；化合物 GABAA receptor agent 2 TFAGABAA receptor agent 2 TFA
GABAA receptor agent 2 TFA is a potent, high-affinity GABAA receptor antagonist with an IC50 of 24 nM (human α1β2γ2GABAA-expressing tsA201 cells) and a Ki of 28 nM (rat GABAA receptor). GABAA receptor agent 2 TFA has no effect on four human GABA transport proteins (hGAT-1, hBGT-1, hGAT-2 and hGAT-3).
价 格：￥电议型 号：T62426产 地：中国大陆
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T61668GABAA receptor agent 5；化合物 GABAA receptor agent 5GABAA receptor agent 5
GABAA Receptor Agent 5 (compound 018) serves as a potent γ-GABAAR antagonist, possessing a Ki of 0.020 μM. This compound exhibits γ-GABAAR antagonist properties, yet it demonstrates low cellular membrane permeability [1].
价 格：￥电议型 号：T61668产 地：中国大陆
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T61625GABAA receptor agonist 2；化合物 GABAA receptor agonist 2GABAA receptor agonist 2
GABAA receptor agonist 2 (compound 4c) is a highly potent GABAA receptor agonist which exhibits anti-depressive properties in classical mouse models of depression, such as the FST and TST. By binding to the GABA binding site on the GABAA receptor, GABAA receptor agonist 2 produces GABAergic effects. Notably, Compound 4c holds promise for depression research [1].
价 格：￥电议型 号：T61625产 地：中国大陆
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T61052GABAA receptor agent 7；化合物 GABAA receptor agent 7GABAA receptor agent 7
GABAA receptor agent 7 (compoud 5c) has anticonvulsant activity both in vitro and in vivo with low neurotoxicity which can be used in epilepsy research. GABAA receptor agent 7 is a potent positive modulator of GABAA receptor [1].
价 格：￥电议型 号：T61052产 地：中国大陆
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T60842GABAA receptor agonist 1；化合物 GABAA receptor agonist 1GABAA receptor agonist 1
GABAA receptor agonist 1 (compound 3e) is a potent agonist of GABAA receptor that binds at the GABA binding site of GABAA receptor to produce GABAergic effects. GABAA receptor agonist 1 has anti-depression activities in classical mouse models of FST and TST depression that has the potential in the research of depression [1].
价 格：￥电议型 号：T60842产 地：中国大陆
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T60826GABAA receptor agent 8；化合物 GABAA receptor agent 8GABAA receptor agent 8
GABAA receptor agent 8 (compoud 5e) has the potential in epilepsy research. GABAA receptor agent 8 is a potent positive modulator of GABAA receptor with anticonvulsant activity both in vitro and in vivo as well as low neurotoxicity [1].
价 格：￥电议型 号：T60826产 地：中国大陆
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T60817GABAA receptor agent 6；化合物 GABAA receptor agent 6GABAA receptor agent 6
GABAA receptor agent 6 (compound 2027) is a potent γ-GABAAR antagonist with low cellular membrane permeability (Ki = 0.56 μM) [1].
价 格：￥电议型 号：T60817产 地：中国大陆
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T60481GABAA receptor agent 4；化合物 GABAA receptor agent 4GABAA receptor agent 4
GABAA receptor agent 4 (compound 1e) is a potent antagonist of γ-GABAAR with Ki of 0.18 ?M. GABAA receptor agent 4 has immunomodulatory potential which was shown to efficiently rescue the inhibition of T cell proliferation [1].
价 格：￥电议型 号：T60481产 地：中国大陆
