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T6845GNE-317inhibit,GNE-317,Inhibitor,Phosphoinositide 3-kinase,Mammalian target of Rapamycin,mTOR,GNE 31
GNE-317, a PI3K/mTOR inhibitor, can pass through the blood-brain barrier (BBB).
价 格:¥电议型 号:T6845产 地:中国大陆
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T21818Pregnenolone CarbonitrileCYPs,Cytochrome P450,P4503A,orally,Pregnenolone Carbonitrile,Pregnenolone 1
Pregnenolone Carbonitrile is an activator of rodent-PXR and induces the expression of CYP3A.
价 格:¥电议型 号:T21818产 地:中国大陆
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T9379L-Threonic acid magnesium saltL Threonic acid magnesium salt,LThreonic acid magnesium salt
L-Threonic acid magnesium salt (L-TAMS) increases synapse density and memory ability in both aged rats and late stage Alzheimer’s disease (AD) model mice.
价 格:¥电议型 号:T9379产 地:中国大陆
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T8386Esomeprazole Magnesium trihydrateinhibit,K+-ATPase,Esomeprazole magnesium,antioxidant,Proton Pump,(S
Esomeprazole Magnesium trihydrate is a proton pump inhibitor indicated for the short-term treatment of gastroesophageal reflux disease in patients with a history of erosive esophagitis.Esomeprazole magnesium trihydrate acts as an exosome inhibitor by blocking the exosome release via the inhibition of V-H+-ATPases
价 格:¥电议型 号:T8386产 地:中国大陆
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T40864Magnesium sulfateMagnesium sulfate
Magnesium sulfate is currently the anticonvulsant of choice for the prevention and control of eclamptic fits. Magnesium sulfate is also widely used as a tocolytic agent.
价 格:¥电议型 号:T40864产 地:中国大陆
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T7052GnetolTGF-β,antidiabetic,Cyclooxygenase,anticancer,HDAC,antiproliferative,antinociceptive,Inhibitor,
Gnetol competitivity inhibits butyrylcholinesterase (IC50: 1.3 uM). Gnetol has a strong inhibitory effect on murine tyrosinase activity. Gnetol significantly suppresses melanin biosynthesis in murine B16 melanoma cells. It is active in the inhibition of arachidonic acid (AA)-induced platelet aggregation.
价 格:¥电议型 号:T7052产 地:中国大陆
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TQ0079GNE-495MAPK Kinase Kinase Kinase,MAP4K,inhibit,GNE-495,GNE 495,GNE495,Inhibitor
GNE-495 is a potent and specific MAP4K4 inhibitor (IC50: 3.7 nM).
价 格:¥电议型 号:TQ0079产 地:中国大陆
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T9585GNE-9815
GNE-9815 is a high kinase-selective inhibitor of RAF and targets KRAS-mutant cancers through combination therapy.
价 格:¥电议型 号:T9585产 地:中国大陆
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T7166GNE-493GNE493,Mammalian target of Rapamycin,PI3K,Inhibitor,inhibit,GNE-493,Phosphoinositide 3-kinase
GNE-493 is potent, selective, and orally available PI3K and mTOR inhibitor with potential anticancer activity.IC50s of 3.4 nM, 12 nM, 16 nM, 16 nM and 32 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR,respectively.
价 格:¥电议型 号:T7166产 地:中国大陆
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TC0019Pregnenolone acetatePregnenolone acetate
Pregnenolone acetate is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. It acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. It can protect the brain from cannabis intoxication
价 格:¥电议型 号:TC0019产 地:中国大陆
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T7098BAPTAchelator,buffer,BAPTA,magnesium,Phospholipase,inhibit,Inhibitor,calcium
BAPTA is a neuroprotective agent in cerebral ischemia, acting as an intercellular Ca2+ chelator.
价 格:¥电议型 号:T7098产 地:中国大陆
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T60079GNE-064
GNE-064 is a selective, orally active and highly soluble inhibitor of SMARCA4, SMARCA2 and PBRM1 bromodomains 5. GNE-064 inhibits SMARCA4 with an IC50 of 0.035 μM and inhibits SMARCA2 with an EC50 of 0.10 μM. GNE-064 possess Kds with 0.01, 0.016, 0.018 and 0.049 μM for SMARCA4, SMARCA2, PBRM1 bromodomains 5 and PBRM1 bromodomains 2, repectively. GNE-064 can be used as a chemical probe for the research of drug synthesis.
价 格:¥电议型 号:T60079产 地:中国大陆
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T793116a,17a-Epoxy-4-Pregnen-3,20-Dione16a,17a Epoxy 4 Pregnen 3,20 Dione,16a,17aEpoxy4Pregnen3,20Dione
16a,17a-Epoxy-4-Pregnen-3,20-Dione is a chemical compound.
价 格:¥电议型 号:T7931产 地:中国大陆
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TQ0014GNE-131Na+ channels,inhibit,GNE131,Na channels,Inhibitor,Sodium Channel,GNE-131,GNE 131
GNE-131 is a potent and specific inhibitor of human sodium channel NaV1.7 (IC50: 3 nM).
价 格:¥电议型 号:TQ0014产 地:中国大陆
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T9504MAP4343inhibit,microtubule-associated,Microtubule/Tubulin,Pregnenolone,MAP2,tubulin,polymerization,n
Map4343 is a 3-methyl ether derivative of pregnenolone. Map4343 binds to microtubule associated protein 2 (MAP2) in vitro and stimulates tubulin polymerization, resulting in enhanced neurite extension and protection of neurons from neurotoxic agents.
价 格:¥电议型 号:T9504产 地:中国大陆
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T6031GNE0877GNE-0877;GNE 0877
GNE-0877 is a highly effective and specific leucine-rich repeat kinase 2 (LRRK2) inhibitor (Ki: 0.7 nM).
价 格:¥电议型 号:T6031产 地:中国大陆
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T5461GNE-6640GNE 6640;GNE6640
GNE-6640 is a non-covalent inhibitor of ubiquitin epecific peptidase 7 (USP7), with IC50 values of 0.75 μM, 0.43 μM, 20.3 μM and 0.23 μM for full length USP7, USP7 catalytic domain, full length USP43 and Ub-MDM2, respectively.
价 格:¥电议型 号:T5461产 地:中国大陆
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T4512Magnesium glycinate甘氨酸镁;Magnesium diglycinate;magnesium 2-aminoacetate
Magnesium glycinate is a supplement that boost magnesium levels in people with a deficiency of the mineral. Magnesium is a vital nutrient for regulating many body processes, including muscle and nerve function, blood sugar levels, and blood pressure. This
价 格:¥电议型 号:T4512产 地:中国大陆
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T4335GNE-617GNE617;GNE 617
GNE-617, a specific NAMPT inhibitor(IC50=5 nM), shows potency in xenograft models of cancer.
价 格:¥电议型 号:T4335产 地:中国大陆