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  • T11444GNF-6231GNF6231,GNF 6231

    GNF-6231 is a potent, selective, and orally bioavailable Porcupine inhibitor that blocks Wnt signaling.

    价 格：￥电议型 号：T11444产 地：中国大陆

  • T40187GNF2133β-cell,RIP-DTA mice,Inhibitor,insulin secretion,GNF2133,inhibit,Dual specificity tyrosine reg

    GNF2133 is an effective and selective inhibitor of DYRK1A with IC50s of 6.2 nM. GNF2133 can be used in studies about type 1 diabetes.

    价 格：￥电议型 号：T40187产 地：中国大陆

  • T6097GNF-5837GNF5837；GNF 5837

    GNF-5837 is a specific, and orally bioavailable pan-TRK inhibitor for TrkA/TrkB (IC50: 8/12 nM).

    价 格：￥电议型 号：T6097产 地：中国大陆

  • T3439ML348GNF-Pf-1127

    ML348 is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM).

    价 格：￥电议型 号：T3439产 地：中国大陆

  • T3196GNF-7GNF7；GNF 7

    GNF-7 is Bcr-Abl WT and Bcr-Abl T315I inhibitor with IC50 of 133 nM and 61 nM, respectively.

    价 格：￥电议型 号：T3196产 地：中国大陆

  • T1817GNF-2GNF2；GNF 2

    GNF-2 is a highly selective non-ATP competitive inhibitor of Bcr-Abl.

    价 格：￥电议型 号：T1817产 地：中国大陆

  • T1803GNF-5GNF 5；GNF5

    GNF-5 is a specific non-ATP competitive inhibitor of Bcr-Abl (IC50: 0.22±0.1 uM, Wild-type Abl). It is an analog of GNF-2 with improved pharmacokinetic properties.

    价 格：￥电议型 号：T1803产 地：中国大陆

  • T15410GNF351

    GNF351 is a full antagonist of the aryl hydrocarbon receptor (AHR)with the capacity to inhibit both DRE-dependent and -independent activity. GNF351 is minimal toxicity in mouse or human keratinocytes. GNF351 competes with a photoaffinity AHR ligand for bi

    价 格：￥电议型 号：T15410产 地：中国大陆

  • T15409GNF179

    GNF179 is an optimized 8,8-dimethyl IP analog. It exhibited the potency(4.8 nM against the multidrug resistant strain W2) in vitro metabolic stability and in vivo oral bioavailability.

    价 格：￥电议型 号：T15409产 地：中国大陆

  • T11826LCH-7749944GNF-PF-2356

    LCH-7749944 effectively suppresses the proliferation of human gastric cancer cells through downregulation of PAK4/c-Src/EGFR/cyclin D1 pathway and induces apoptosis. LCH-7749944 is a potent PAK4 inhibitor with an IC50 of 14.93 μM.

    价 格：￥电议型 号：T11826产 地：中国大陆

  • T11447GNF4877

    GNF4877 is a potent DYRK1A and GSK3β inhibitor (IC50s: 6 nM and 16 nM). It leads to blockade of nuclear factor of activated T-cells (NFATc) nuclear export and increased β-cell proliferation cells.

    价 格：￥电议型 号：T11447产 地：中国大陆

  • T10199GNF-PF-37778-Nitrotryptanthrin

    GNF-PF-3777 (8-Nitrotryptanthrin) is a potent inhibitor of human indoleamine 2,3-dioxygenase 2 (hIDO2; Ki: 0.97 μM).

    价 格：￥电议型 号：T10199产 地：中国大陆

  • T10199GNF-PF-3777GNF-PF-3777,8-Nitrotryptanthrin,

    GNF-PF-3777 (8-Nitrotryptanthrin) is a potent inhibitor of human indoleamine 2,3-dioxygenase 2 (hIDO2; Ki: 0.97 μM).

    价 格：￥电议型 号：T10199产 地：美洲

  • T11444GNF-6231GNF-6231

    GNF-6231 shows IC50s of greater than 10 μM on all CYP isoforms tested .?GNF-6231 have favorable potency and a PK profile across preclinical species upon oral administration.?The reference for orally in MMTV-Wnt1 tumor bearing mice is dosed at 3 mg/kg.?GNF

    价 格：￥电议型 号：T11444产 地：美洲

  • T11446GNF362GNF362

    GNF362 also inhibits Itpka and Itpkc with IC50 values of 20 nM and 19 nM, respectively.?Inositol trisphosphate 3’ kinase B (Itpkb) is a Ca2+-dependent kinase, which phosphorylates the 3’ position of Ins (1,4,5) P3 to generate inositol 1,3,4,5-tetrakisphos

    价 格：￥电议型 号：T11446产 地：美洲

  • T11447GNF4877GNF4877

    GNF4877?leads to blockade of nuclear factor of activated T-cells (NFATc) nuclear export and increased β-cell proliferation cells.?GNF4877 is a potent DYRK1A and GSK3β inhibitor with IC50s of 6?nM and 16?nM, respectively.

    价 格：￥电议型 号：T11447产 地：美洲

  • T11826LCH-7749944LCH-7749944,GNF-PF-2356,

    LCH-7749944 effectively suppresses the proliferation of human gastric cancer cells through downregulation of PAK4/c-Src/EGFR/cyclin D1 pathway and induces apoptosis.?LCH-7749944 is a potent PAK4 inhibitor with an IC50 of 14.93 μM.?

    价 格：￥电议型 号：T11826产 地：美洲

  • T15410GNF351GNF351

    GNF351 is a full antagonist of the aryl hydrocarbon receptor (AHR). GNF351 is minimal toxicity in mouse or human keratinocytes. GNF351 competes with a photoaffinity AHR ligand for binding to the AHR (IC50: 62 nM).

    价 格：￥电议型 号：T15410产 地：美洲

  • T1803GNF-5GNF-5,GNF5,GNF 5

    GNF-5 is a specific non-ATP competitive inhibitor of Bcr-Abl (IC50: 0.22±0.1 uM, Wild-type Abl). It is an analog of GNF-2 with improved pharmacokinetic properties.

    价 格：￥电议型 号：T1803产 地：美洲

  • T1817GNF-2GNF-2,GNF2,GNF 2

    GNF-2 is a highly selective non-ATP competitive inhibitor of Bcr-Abl.

    价 格：￥电议型 号：T1817产 地：美洲

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