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T9766GW590735lipid,LDLc,GW-590735,GW 590735,HDLc,Peroxisome proliferator-activated receptors,GW590735,PPA
GW590735 is an effective and selective PPARα agonist with an EC50 of 4 nM on PPARα and at least 500-fold selectivity versus PPARδ and PPARγ. GW590735 can be used in dyslipidemia studies.
价 格:¥电议型 号:T9766产 地:中国大陆
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T69408GW590735 sodium;化合物 GW590735 sodiumGW590735 sodium
GW590735 is a potent and selective agonist of PPARα with an EC50 value of 4 nM for the expression a GAL4-responsive reporter gene and at least 500-fold selectivity versus PPARγ and PPARδ. GW590735 significantly increased HDL cholesterol, decreased LDL and VLDL cholesterol, and significantly reduced triglycerides. Maximal increases in HDL cholesterol were 37%, 53%, and 84% with fenofibrate, torcetrapib, and GW590735, respectively.
价 格:¥电议型 号:T69408产 地:中国大陆