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T38011C2 Adamantanyl Globotriaosylceramide (d18:1/2:0);C2 Adamantanyl Globotriaosylceramide (d18:1/2:0)C2
C2 Adamantanyl globotriaosylceramide (AdaGb3) is a bioactive sphingolipid and water-soluble form of globotriaosylceramide that contains an adamantanyl group in place of the fatty acyl chain. It inhibits Vero toxin binding to globotriaosylceramide in an ELISA assay when used at a concentration of 10 μM. AdaGb3 decreases cell surface expression of P-glycoprotein (P-gp) and reduces efflux of rhodamine 123 in MDCK cells. It also increases apical-to-basal transport of vinblastine in human intestinal
价 格:¥电议型 号:T38011产 地:中国大陆
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T37439C18 Globotriaosylceramide (d18:1/18:0);C18 Globotriaosylceramide (d18:1/18:0)C18 Globotriaosylcerami
C18 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from lactosylceramide . It inhibits aggregation of human neutrophils induced by phorbol 12-myristate 13-acetate (PMA; 10008014) when used at a concentration of 1 μM. C18 globotriaosylceramide acts as a receptor for Shiga toxin in B cell-derived Raji cells and THP-1 monocytes. It accumulates in the brain, heart, kidney, liver, lung, and spleen in a mouse model of Fabry disease, a lysosoma
价 格:¥电议型 号:T37439产 地:中国大陆
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T37438C17 Globotriaosylceramide (d18:1/17:0);C17 Globotriaosylceramide (d18:1/17:0)C17 Globotriaosylcerami
C17 Globotriaosylceramide is a sphingolipid that has been used as an internal standard for the quantification of globotriaosylceramides in plasma and urine from patients with Fabry disease by GC-MS.
价 格:¥电议型 号:T37438产 地:中国大陆
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T37291Lyso-Globotriaosylceramide (d18:1);Lyso-Globotriaosylceramide (d18:1)Lyso-Globotriaosylceramide (d18
Lyso-globotriaosylceramide is a form of globotriaosylceramide that is lacking the fatty acyl group. It binds to Shiga toxin 1 (Stx1) in the presence of cholesterol and phosphatidylcholine but does not bind Stx2. It also reduces viability and aggregation of human neutrophils induced by phorbol 12-myristate 13-acetate when used at concentrations of 50 and 1 μM, respectively. Lyso-globotriaosylceramide accumulates in the brain, heart, kidney, liver, lung, and spleen in a mouse model of Fabry diseas
价 格:¥电议型 号:T37291产 地:中国大陆
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T36859C16 Globotriaosylceramide (d18:1/16:0);C16 Globotriaosylceramide (d18:1/16:0)C16 Globotriaosylcerami
C16 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from C16 lactosylceramide . C16 globotriaosylceramide acts as a receptor for Shiga toxin in B cell-derived Raji cells and THP-1 monocytes. It accumulates in endothelial cells, pericytes, vascular smooth muscle cells, renal epithelial cells, dorsal ganglia neuronal cells, and myocardial cells in patients with Fabry disease. C16 globotriaosylceramide is also upregulated in plasma of patien
价 格:¥电议型 号:T36859产 地:中国大陆
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T36186Globotriaosylceramides (porcine);Globotriaosylceramides (porcine)Globotriaosylceramides (porcine)
Globotriaosycleramides are glycosphingolipids found in mammalian cell membranes that are synthesized from lactosylceramides . They act as receptors for Shiga and Shiga-like toxins in vitro and in vivo. Globotriaosylceramides accumulate in endothelial cells, pericytes, vascular smooth muscle cells, renal epithelial cells, dorsal ganglia neuronal cells, and myocardial cells in patients with Fabry disease, a lysosomal storage disorder characterized by a deficiency in the enzyme α-galactosidase A. G
价 格:¥电议型 号:T36186产 地:中国大陆
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T36185Globotriaosylceramides (hydroxy) (porcine);Globotriaosylceramides (hydroxy) (porcine)Globotriaosylce
Globotriaosycleramides are glycosphingolipids found in mammalian cell membranes that are synthesized from lactosylceramides . They act as receptors for Shiga and Shiga-like toxins in vitro and in vivo. Globotriaosylceramides accumulate in endothelial cells, pericytes, vascular smooth muscle cells, renal epithelial cells, dorsal ganglia neuronal cells, and myocardial cells in patients with Fabry disease, a lysosomal storage disorder characterized by a deficiency in the enzyme α-galactosidase A. G
价 格:¥电议型 号:T36185产 地:中国大陆